Myopia control effect of defocus incorporated multiple segments (DIMS) spectacle lens in Chinese children: results of a 3-year follow-up study

Abstract

AimsTo determine myopia progression in children who continued to wear the defocus incorporated multiple segments (DIMS) lenses or switched from single vision (SV) to DIMS lenses for a 1-year period following a 2-year myopia control trial.Methods128 children participated in this study. The children who had worn DIMS lenses continued to wear DIMS lenses (DIMS group), and children who had worn SV lenses switched to wear DIMS lenses (Control-to-DIMS group). Cycloplegic spherical equivalent refraction (SER) and axial length (AL) were measured at 6-month interval. Historical controls were age matched to the DIMS group at 24 months and used for comparing the third-year changes.ResultsOver 3 years, SER and AL changes in the DIMS group (n=65) were −0.52±0.69D and 0.31±0.26 mm; these changes were not statistically significant over time (repeated measures analysis of variance, p>0.05).SER (−0.04±0. 38D) and AL (0.08±0.12 mm) changes in the Control-to-DIMS group (n=55) in the third year were less compared with the first (mean difference=0.45 ± 0.30D, 0.21±0.11 mm, p<0.001) and second (0.34±0.30D, 0.12±0.10 mm, p<0.001) years.Changes in SER and AL in both groups over that period were significantly less than in the historical control group (DIMS vs historical control: mean difference=−0.18±0.42D, p=0.012; 0.08±0.15 mm, p=0.001; Control-to-DIMS versus historical control: adjusted mean differences=−0.30±0.42D, p<0.001; 0.12±0.16 mm, p<0.001).ConclusionsMyopia control effect was sustained in the third year in children who had used the DIMS spectacles in the previous 2 years and was also shown in the children switching from SV to DIMS lenses.

Effect of Repeated Low-Level Red-Light Therapy for Myopia Control in Children

“…A further report has shown that this myopia control effect is sustained in the third year. 13,27 While study design differences make direct comparison difficult, the RLRL efficacy results reported here appear at least competitive with these other treatment modalities.…”

“…The inclusion and exclusion criteria adopted were the same as for the majority of myopia control trials conducted for low dose atropine eyedrops 12 and defocus incorporated multiple segments (DIMS) spectacle lens 13 , in order to ensure outcomes were comparable across studies. Eligible participants were children aged 8 to 13 years with myopia of cycloplegic spherical equivalent refraction (SER) of -1.00 to -5.00 diopters (D), astigmatism < 2.50 D, anisometropia < 1.50 D, best-corrected visual acuity (BCVA) > 0.0 logMAR (Snellen 1.0 or 20/20) in either eye, and were willing to J o u r n a l P r e -p r o o f participate in the study and accept random allocation in grouping.…”

Influence of coronavirus disease 2019 on myopic progression in children treated with low-concentration atropine

“…In addition to genetic susceptibility, several environmental factors, such as prolonged near work, increased digital screen time, and insufficient time spent outdoors, are recognized as important risk factors for myopic progression [1][2][3][4]. To control the epidemic of myopia, low-concentration atropine eye drops and specially designed contact lenses and spectacle lenses, such as defocus incorporated multiple segments (DIMS) lenses and aspherical lenslets, are recommended to reduce myopic progression and have now reached high levels of evidence [5][6][7].…”

Myopietherapie und Prophylaxe mit „Defocus Incorporated Multiple Segments“-Brillengläsern

“…Zusätzlich sind in Abb. 3 die aus aktuellen Studiendaten ermittelten mittleren Wachstumsraten der Studien zu den DIMS-Gläsern [ 18 , 20 ], aus der LAMP-Studie (Yam et al. 2020) zur Wirkung von Atropin-Augentropfen auf die Myopieprogression [ 35 ], aus der ROMIO-Studie (Cho et al.…”

“…Gemäß Abb. 3 , nach aktueller Studienlage, erfüllt allein die DIMS-Brille im Beobachtungszeitraum [ 18 , 20 ] das hier vorgestellte praktische Therapiekriterium vollständig, während die Therapie mit 0,05 % Atropin [ 35 ] und danach die Ortho-K-Therapie [ 10 ] und die Therapie mit „High Add“-multifokalen Kontaktlinsen [ 29 ] eine noch tolerierbare Therapieperformance erreichen können. Wie aber kürzlich von Joachimsen et al berichtet [ 14 ], müsse eine Atropin-Konzentration von 0,05 % bei kaukasischen Kindern aufgrund der Nebenwirkungen in der praktischen klinischen Anwendung als kritisch eingestuft werden.…”