Myogenic Satellite Cells and Its Application in Animals - A Review

Abstract

Myogenic satellite cells have been isolated and identified by several recently elucidated molecular markers.Furthermore, knowledge about the precise function of these markers has provided insight into the early and terminal events of satellite cells during proliferation, differentiation, transdifferentiation, specification and activation. Recently, quiescent myogenic satellite cells have been associated with possession of Pax 3 and 7 that represent pluripotent stem cells capable of differentiating into other lineages. However, the mechanism by which myogenic satellite cells attain pluripotent potential remain elusive. Later, transdifferentiating ability of these cells to another lineage in the absence or presence of certain growth factor/ or agents has revolutionized the scope of these pluripotent myogenic satellite cells for manipulation of animal production (in terms of quality and quantity of muscle protein) and health (in terms of repair of skeletal muscle, cartilage or bone).

Embryonic Development and Histological Analysis of Skeletal Muscles of Tenuidactylus caspius (Eichwald, 1831) Lizards (Reptilia: Squamata)

“…Some myoblasts are not involved in the formation of myotubules [12]. These cells remain between the basement membrane [13] and the plasma membrane of the muscle fiber [14], creating myosatellite cells [15]. Satellite cells are more common in the muscle fibers of the lizard tail.…”

A Comparative Study on the Adipogenic and Myogenic Capacity of Muscle Satellite Cells, and Meat Quality Characteristics between Hanwoo and Vietnamese Yellow Steers

“…(Jiwlawat et al, 2018). Another population of myoblasts known as satellite cells, are found in postnatal skeletal muscles and are positioned beneath the basement membrane of the myofibers (Singh et al, 2009). At birth, the number of satellite cells accounts for about 30-35% of total muscle fiber nuclei in animals (Day et al, 2010).…”