Myocarditis and Pericarditis

Knowlton, Kirk U.; Savoia, Maria C.; Oxman, Michael N.

doi:10.1016/b978-0-443-06839-3.00081-3

Cited by 9 publications

(18 citation statements)

References 638 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Bununla birlikte bu test hastamızda negatifti. Perikardiyal sıvıdan EBV DNA tespiti perikardit tanısında yardımcıdır (2). Biz ise tanıyı serum anti-EBV VCA IgM pozitifliğiyle koyduk.…”

Section: İrdelemeunclassified

Pericarditis Developing After Epstein-Barr Virus Infection: A Case Report

Şahin¹,

Boşnak²,

Şahin³

et al. 2016

Klimik Dergisi

View full text Add to dashboard Cite

GirişAkut perikardit, infeksiyöz ve noninfeksiyöz nedenlere bağlı olarak gelişebilen bir klinik tablodur. İnfeksiyöz perikardit olgularının en sık nedeni viruslardır. Özellikle koksakivirus ve ekovirusların da bulunduğu enterovirus ailesi en sık infeksiyöz etkenlerdir. Akut perikardit, sistemik bir hastalığa bağlı olmadığında ve immün yetmezlik tablosu bulunmadığında genellikle kendini sınırlayan bir hastalıktır (1-3). Epstein-Barr virusu (EBV) infeksiyonuna bağlı perikardit ise oldukça nadir görülen bir durumdur (4). Bu yazıda, immün yetmezliğin olmadığı bir zeminde EBV infeksiyonuna bağlı olarak perikardiyal ve plevral efüzyon gelişen genç bir erkek olgu sunuldu. OlguOtuz dört yaşında erkek hasta son iki gündür var olan ateş, boğaz ağrısı, halsizlik ve nefes alıp vermekle artan göğüs ağrısı şikayetiyle hastanemize başvurdu. Ateş etyolojisini araştırmak için yatırılan hastanın yaklaşık dört gün boyunca ateşi devam etti. Fizik muayenede kan basıncı 90/60 mmHg, nabız 120/dakika ve ritmik, ateş 38°C, solunum sayısı 30/dakika idi. Fizik muayenede farinkste hiperemi vardı. Dinlemekle bilateral alt zonlarda solunum seslerinin azalması dışında başka patolojik bulgu saptanmadı. Hepatosplenomegali saptanmadı; servikal, aksiller ve inguinal lenfadenomegali yoktu. Laboratuvar tetkiklerinde lökosit 12 800/mm 3 (%49 nötrofil, %40 lenfosit, %10 monosit), hemoglobin 11.6 gr/dl, aspartat aminotransferaz 25 Ü/lt, alanin aminotransferaz 161 Ü/lt, eritrosit sedimantasyon hızı (ESR) 112 mm/saat, C-reaktif protein (CRP) 97 mg/lt ve laktat dehidrogenaz 625 Ü/lt ölçüldü. Tiroid fonksiyon testleri normal, bruselloz için standard tüp aglütinasyon testi, tümör belirteçleri, anti-nükleer antikor, anti-dsDNA negatif olarak bulundu. Hemokültürlerde üre-me olmadı. Periferik yaymada lenfositoz saptandı; atipik hücre görülmedi. Genel durumu stabil olmayan hastaya çekilen toraks bilgisayarlı tomografisi (BT)'nde paratrakeal, prevasküler, hiler ve karinal bölgelerde en büyüğü 1.5 cm olan lenfadenomegali izlendi. Akciğer parenkiminde buzlu cam dansiteleri, sağda lineer atelektazi görünümle-ri ve bilateral plevral sıvı saptandı. Perikardiyal alanda en geniş yerinde 2 cm kalınlığa ulaşan perikardiyal efüzyon ve kardiyotorasik oran kalp lehine artmış olarak izlendi (Resim 1). Transtorasik ekokardiyografide kalp kapakları doğal ve ejeksiyon fraksiyonu %60'tı; vejetasyon saptanmadı. Kalbi çepeçevre saran perikardiyal efüzyon izlendi. AbstractAcute pericarditis may be infectious or noninfectious, and the most common agents are viruses. A 34-year-old male was admitted to hospital with fever, respiratory distress and chest pain while breathing. Echocardiography showed pericardial effusion, thoracic computed tomography demonstrated pleural effusion.

show abstract

Section: İrdelemeunclassified

Pericarditis Developing After Epstein-Barr Virus Infection: A Case Report

Şahin¹,

Boşnak²,

Şahin³

et al. 2016

Klimik Dergisi

View full text Add to dashboard Cite

show abstract

“…Coxsackie group A viruses can cause aseptic meningitis in adults, and commonly infect skin and mucous membranes in herpangina, conjunctivitis and hand, foot and mouth disease in children [ 1 ]. Group B viruses cause herpangina, pleurodynia, and infect the heart, pancreas, and liver which can give rise to myocarditis, pericarditis, pancreatitis and hepatitis in adults [ 2 ]. Viral pericarditis is inflammation of the pericardium or the lining surrounding the heart that is caused by viral infections [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

“…Group B viruses cause herpangina, pleurodynia, and infect the heart, pancreas, and liver which can give rise to myocarditis, pericarditis, pancreatitis and hepatitis in adults [ 2 ]. Viral pericarditis is inflammation of the pericardium or the lining surrounding the heart that is caused by viral infections [ 2 ]. Coxsackie B viruses are the most common cause of myocarditis and pericarditis in adults and have been identified in up to 50 % of viral cardiac cases [ 3 – 5 ].…”

Section: Introductionmentioning

confidence: 99%

“…Coxsackie B viruses are the most common cause of myocarditis and pericarditis in adults and have been identified in up to 50 % of viral cardiac cases [ 3 – 5 ]. A number of other viral, bacterial, and fungal infections as well as medications has also been shown to cause myocarditis and pericarditis [ 2 , 6 ]. However, the presentation of this viral infection is rare among patients with isolated pancreatitis or hepatitis [ 7 – 11 ].…”

Section: Introductionmentioning

confidence: 99%

“…Notably, viral pericarditis can lead to pericardial constriction as a late complication [ 12 , 13 ]. Constrictive pericarditis with effusion has been detected in ten percent of patients with clinical tamponade [ 2 ]. Coxsackie B viruses usually cause various single organ system diseases, but the combination of myocarditis, pancreatitis and hepatitis has been documented in two case reports [ 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Effusive-constrictive pericarditis, hepatitis, and pancreatitis in a patient with possible coxsackievirus B infection: a case report

et al. 2016

View full text Add to dashboard Cite

BackgroundCoxsackie B is a viral pathogen that presents with various invasive diseases in adults. Historically, the majority of adult cases with pericarditis or myocarditis have been attributed to coxsackievirus B. The presentation of this viral infection causing effusive-constrictive pericarditis, hepatitis or pancreatitis is rare. This case report is the first to describe a patient with concomitant effusive-constrictive pericarditis, hepatitis and pancreatitis from possible coxsackievirus B infection.Case presentationA 26-year old female was admitted to our hospital with the diagnosis of effusive-constrictive pericarditis complicated by tamponade and cardiac arrest. An emergent pericardiocentesis was performed successfully. Hepatitis and pancreatitis were also identified in our patient. After an extensive workup, coxsackievirus B infection was suspected by positive serum complement fixation antibody titers. Our patient made a full recovery and was discharged from the hospital.ConclusionClinical suspicion of effusive-constrictive pericarditis with tamponade from coxsackievirus B should be considered in patients presenting with chest pain, dyspnea, jugular venous distention, hypotension, ST segment elevation on electrocardiogram, and ventricular interdependence with septal shift during diastole on transthoracic echocardiogram. Initial diagnoses of effusive-constrictive pericarditis resembling cardiac tamponade, hepatitis and pancreatitis can be challenging, and this case highlights the need for healthcare professionals to be cognizant of the association between these unusual clinical presentations and coxsackievirus B infection.Electronic supplementary materialThe online version of this article (doi:10.1186/s12879-016-1752-3) contains supplementary material, which is available to authorized users.

show abstract