“…b-blockade during myocardial ischemia reperfusion may also induce metabolic changes, such as reduced release of free fatty acids (FFA), during reperfusion and decreased myocardial lactate production. Plasma levels of FFA increase during myocardial ischemia reperfusion [5] and may trigger ventricular arrhythmias [19] and may impair activity of Ca 2+ pumps in sarcoplasmic reticulum [20]. The maximal level of FFA is reached during reperfusion [5].…”
Myocardial salvage may be significantly enhanced by CPB and esmolol, even when treatment with esmolol is initiated as late as with the onset of reperfusion.
“…b-blockade during myocardial ischemia reperfusion may also induce metabolic changes, such as reduced release of free fatty acids (FFA), during reperfusion and decreased myocardial lactate production. Plasma levels of FFA increase during myocardial ischemia reperfusion [5] and may trigger ventricular arrhythmias [19] and may impair activity of Ca 2+ pumps in sarcoplasmic reticulum [20]. The maximal level of FFA is reached during reperfusion [5].…”
Myocardial salvage may be significantly enhanced by CPB and esmolol, even when treatment with esmolol is initiated as late as with the onset of reperfusion.
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