“…Our light microscopic examination of left ventricular myocytes showed disorganized cardiac muscle fibers, cellular necrosis and vacuolar degeneration after 2 weeks of RVP. Furthermore, electron microscopy revealed that significant changes were found in mitochondria, including markedly decreased matrix density, distinct mitochondrial swelling with significant disruption or disappearance of cristae, and vacuolar degeneration, which was in consistent with the study by Song et al…”