Myocardial infarction in a young adult due to Kawasaki disease. A case report and review of the late cardiological sequelae of Kawasaki disease

Shaukat, N; Ashraf, Syed Jibran; Mebewu, Anthony; Freemont, Anthony J.; Keenan, Danniel

doi:10.1016/0167-5273(93)90044-h

Cited by 12 publications

(2 citation statements)

References 11 publications

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“…Coronary artery occlusion with subsequent myocardial infarction or coronary artery rupture and death can occur from the presence of coronary artery aneurysm, which may be a late complication of Kawasaki disease [77][78][79] although a history may not be present [80]. Death resulting from coronary arteritis can occur in association with rheumatoid disease, systemic lupus erythematosus giant cell arteritis, Takayasu's arteritis, hereditary angioedma, Wegener's, Churg-Strauss, polyarteritis nodosa (PAN), infection and use of cocaine [81][82][83][84].…”

Section: Introductionmentioning

confidence: 99%

Sudden adult death

Langlois

2009

Forensic Sci Med Pathol

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In the investigation of sudden death in adults, channelopathies, such as long QT syndrome, have risen to the fore in the minds of forensic pathologists in recent years. Examples of these disorders are touched upon in this review as an absence of abnormal findings at postmortem examination is characteristic and the importance of considering the diagnosis lies in the heritable nature of these conditions. Typically, a diagnosis of a possible channelopathy is evoked as an explanation for a 'negative autopsy' in a case of apparent sudden natural death. However, the one potential adverse effect of this approach is that subtle causes of sudden death may be overlooked. The intention of this article is to review and discuss potential causes of sudden adult death (mostly natural) that should be considered before resorting to a diagnosis of possible channelopathy. Nonetheless, it becomes apparent that many of the potential causes of sudden death can have a genetic basis. Thus, it becomes an important consideration that there may be a genetic basis to sudden death that extends beyond the negative autopsy.

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Section: Introductionmentioning

confidence: 99%

Sudden adult death

Langlois

2009

Forensic Sci Med Pathol

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“…11 Additional treatment diseases with the risk of myocardial ischaemia or myocardial infarction. 17 The optimal timing with further courses of IVIG has been found to be safe, 12 but a subgroup of patients for the use of pulse methylprednisolone therapy in IVIG-resistant KD is important remains unresponsive to IVIG re-treatment. Wright et al rst described the outcome in but remains unknown.…”

Section: Discussionmentioning

confidence: 99%

Pulse methylprednisolone therapy in the treatment of immune globulin-resistant Kawasaki disease: case report and review of the literature

Hung

Chiu

2004

Annals of Tropical Paediatrics

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A subgroup of patients with Kawasaki disease (KD) did not respond to intravenous immune globulin (IVIG) therapy. Corticosteroid therapy remains a controversial alternative in such cases. We report two young children with KD who failed to respond to three courses of IVIG therapy and subsequently received pulse methylprednisolone as an alternative. One had a satisfactory outcome but the other developed giant coronary aneurysms and had a myocardial infarction 2 months after onset of the illness. A review of relevant literature showed that the timing of initiation of pulse methylprednisolone therapy is important. It is suggested that pulse methylprednisolone therapy should be considered if there is no response to two standard doses of IVIG treatment.

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Anaesthetic management for Caesarean section in a patient with Kawasaki disease

1995

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Kawasaki disease (KD) Kawasaki disease (KD) is an acute febrile illness that affects primarily infants and young children. It is often associated with a prominent necrotizing vasculitis component with aneurysms of the coronary arteries and peripheral arteries, which may lead to ischaemic heart disease or sudden death. It has been more than 20 yr since this disease was first reported ~ and the patients have now entered adulthood and reached child-bearing age. However, there has been no reported ease of pregnancy in a patient with a history of KD. Nor has the optimal anaesthetic management for Caesarean section in these patients been discussed.We report the successful use of epidural anaesthesia in the management of a term parturient with a history of KD undergoing Caesarean section.Case report A 24-yr-old primipara (gestation 40 wk, weight 73.5 kg) presented for elective Caesarean section because of cephalopelvic disproportion (CPD). She had a history of KD, which had been diagnosed at the age of two years with a couple of weeks of fever, exanthema, and sweUing of cervical, axillary, and femoral lymph nodes. Echocardiography and coronary angiography, both performed at the age of 13 yr, had revealed a giant aneurysm of the left coronary artery and complete occlusion of the fight coronary artery with evidence of collateral circulation. These fmdings were reevahated by echocardiography performed at the age of 16 yr. Exercise stress thallium myocardial scinfigram showed a defect in the left ventricular posterior wall. Although ECG, chest x-ray and the wall motion of the left ventricle at rest were normal, strenuous work had been causing palpitation and sometimes syncopal attacks. She had not been followed up since then CAN J ANAESTH 1995 / 42: ! ! / pp 1024--6

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Myocardial infarction in a young adult due to Kawasaki disease. A case report and review of the late cardiological sequelae of Kawasaki disease

Cited by 12 publications

References 11 publications

Sudden adult death

Sudden adult death

Pulse methylprednisolone therapy in the treatment of immune globulin-resistant Kawasaki disease: case report and review of the literature

Anaesthetic management for Caesarean section in a patient with Kawasaki disease

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