Myocardial Infarction And Ischemic Heart Disease In Patients With Acute Ischemic Stroke

Abstract

SummaryThe aim of the investigation was to analyze the correlation between myocardial infarction and ischemic heart disease, on the one hand, and acute ischemic stroke (AIS), on the other hand. We studied 258 AIS patients (mean age 70.9±7.22 years, range 49-92 years) hospitalized in 2007-2013 in the First Clinic of Neurology, St. Marina University Hospital of Varna. The diagnosis of acute ischemic stroke was confirmed by Doppler sonography and computed tomography of the cerebral circulation. Data were statistically processed by variation and correlation analysis. Our results proved a relatively strong correlation between effort angina pectoris and ischemic heart disease (Pearson's coefficient: r=0.643) as well as a weak correlation between ischemic heart disease and myocardial infarction (Pearson's coefficient: r=0.243) among acute ischemic stroke patients. The well-known risk factors for these cardiovascular diseases such as obesity, tobacco smoking, low physical activity and alcohol abuse were common among the patients with acute ischemic stroke, too. In conclusion, both myocardial infarction and ischemic heart disease are strongly associated with the development of acute ischemic stroke. Such patients require strict and regular control by general practitioners. They should observe an appropriate diet and adhere to a healthy life-style.

The Clinical Outcome Comparison of Ischemic Stroke with and without Ischemic Heart Disease

“…Similarly, in previous study ischemic stroke patients following an ischemic heart disease had increased in-hospital and long-term mortality with in-hospital mortality of 30%, more acute and more extensive deficits, and greater residual deficits at 6 months [8]. Ischemic heart disease was strongly associated with the development of acute ischemic stroke, patients with a history of ischemic heart disease had more than twice the risk of stroke than those who have not [5,9]. Other studies also considered ischemic stroke after ischemic heart disease was an important complication, with a mortality rate of up to 60% at one year [5,8].…”

“…Ischemic heart disease was strongly associated with the development of acute ischemic stroke, patients with a history of ischemic heart disease had more than twice the risk of stroke than those who have not [5,9]. Other studies also considered ischemic stroke after ischemic heart disease was an important complication, with a mortality rate of up to 60% at one year [5,8].…”

“…Ischemic heart disease patients are associated with increased morbidity and mortality [5], but the studies describing clinical outcomes of ischemic heart disease in ischemic stroke patients are a lack. This is the first study to correlate Ischemic heart disease in ischemic stroke with length of stay and functional outcome by using mRS.…”