Mycoplasma gallisepticum Vaccination-Challenge: An Egg-Production Model

Evans, Robert D.; Hafez, Y S; Orthel, F.W.

doi:10.2307/1591555

Cited by 12 publications

(5 citation statements)

References 17 publications

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“…The live F strain vaccine currently on the market is reported to provide good protection for layers [20][21][22], is capable of displacing the pathogenic R strain from infected flocks [23], and can be readily distinguished from field strains [24,25]. However, it has been shown to be pathogenic for young chickens when administered by an aerosol route [26][27][28].…”

Section: Discussionmentioning

confidence: 99%

“…However, it has been shown to be pathogenic for young chickens when administered by an aerosol route [26][27][28]. The 6/85-and ts-11-based vaccines are reported to be safer than the F strain vaccine but do not afford the same level of protection [22,23,[28][29][30]. R high was previously reported to be avirulent for chickens [10] but the genetic changes associated with attenuation were only recently determined on a biochemical and molecular basis by Papazisi et al [11].…”

Section: Discussionmentioning

confidence: 99%

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A modified live Mycoplasma gallisepticum vaccine to protect chickens from respiratory disease

Papazisi

Silbart

Frasca

et al. 2002

Vaccine

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

A modified live Mycoplasma gallisepticum vaccine to protect chickens from respiratory disease

Papazisi

Silbart

Frasca

et al. 2002

Vaccine

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“…Egg production losses in commercial poultry have been well documented for M. gallisepticum, with egg production drops varying between 5 and 50% (Evans et al, 1992;Stipkovits & Kempf, 1996;Kleven, 2003). In contrast, reports on egg production losses due to M. synoviae are scarce, and papers describing a detrimental effect of M. synoviae on egg production (Lott et al, 1978;Morrow et al, 1990) and describing no effect can both be found (Van Eck et al, 1980;Mohammed et al, 1987).…”

Section: Resultsmentioning

confidence: 99%

Induction of eggshell apex abnormalities in broiler breeder hens

Feberwee

Landman

2010

Avian Pathology

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Recently, the causal relationship between eggshell apex abnormalities (EAA) and Mycoplasma synoviae was described. This eggshell pathology has only been documented in table egg layers both spontaneously and experimentally infected with M. synoviae, suggesting that meat-type layers are less prone to this condition. In this study the susceptibility of specified pathogen free (SPF) broiler breeder hens to produce eggs with EAA after M. synoviae infection was assessed. Five groups of 12 hens each were made: a negative control group, a group inoculated intratracheally (i.t.) with a M. synoviae EAA strain at 19 weeks of age, a group inoculated i.t. with this strain at 19 and 26 weeks of age, a group inoculated with M. synoviae i.t. at 19 weeks of age and infected 5 days earlier with infectious bronchitis virus D1466 (IBV), and a fifth group similar to the former but inoculated i.t. twice with an M. synoviae EAA strain at 19 and 26 weeks of age. Eggs with EAA were only produced after a single i.t. inoculation with the M. synoviae EAA strain if preceded by an infection with IBV. The production of eggs with EAA started 6 weeks after M. synoviae EAA inoculation and the proportion of eggs with EAA during the experiment was 9/449 (2%), which was much lower than that in SPF layer hens (14Á22%). The present results suggest that broiler breeder hens are less susceptible to producing eggs with EAA after an infection with a M. synoviae EAA strain preceded by an IBV infection, compared with table egg layers. Similar to SPF egg layers, the mean daily egg production per hen was significantly reduced by the M. synoviae EAA strain and there was a general negative effect on eggshell strength by this strain, suggesting it could also have a detrimental effect on hatching egg quality.

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“…As expected, immunity does play a role in protection from mycoplasma diseases. Vaccination against mycoplasma disease is possible (33)(34)(35)(36)(37)(38)(39)(40)(41). Mucosal IgA responses are likely important in resistance to disease associated with mycoplasma infection of mucosal surfaces (42,43).…”

Section: The Complexity Of Immune Interactions With Mycoplasmamentioning

confidence: 99%

T lymphocyte responses are critical determinants in the pathogenesis and resistance to mycoplasma respiratory disease

Jones

Simecka

2003

Front Biosci

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Mycoplasmas are responsible for many human and animal respiratory diseases and have a tremendous economic and health impact worldwide. Currently, there is no vaccine against any animal or human mycoplasma species. Despite the vast amount of research, the mechanisms that control hosts' resistance and susceptibility to mycoplasma infection remains unclear. Immune responses, particularly T lymphocyte responses, are believed to be critical players in the pathogenesis of mycoplasma disease. In this review, we will highlight the potential roles of T lymphocytes as influential mediators in animal and human mycoplasma pathogenesis and resistance infection.

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Mycoplasma gallisepticum Vaccination-Challenge: An Egg-Production Model

Cited by 12 publications

References 17 publications

A modified live Mycoplasma gallisepticum vaccine to protect chickens from respiratory disease

A modified live Mycoplasma gallisepticum vaccine to protect chickens from respiratory disease

Induction of eggshell apex abnormalities in broiler breeder hens

T lymphocyte responses are critical determinants in the pathogenesis and resistance to mycoplasma respiratory disease

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