Mycobacterium fortuitum as a Cause of Mastoiditis and Wound Infection

Sm, Neitch; Jb, Sydnor; Cj, Schleupner

doi:10.1001/archotol.1982.00790490013003

Cited by 28 publications

(7 citation statements)

References 19 publications

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“…isoniazid and rifampicin). [4,6,7,10] Our case was similar to these cases as it was managed by antitubercular drugs with satisfactory results.…”

Section: Discussionsupporting

confidence: 77%

“…[4][5][6][7][8] Two more related cases were found, one with M. fortuitum and M. chelonei complex [9] and the other where it could not be made out whether the organism was M. fortuitum or Mycobacterium peregrinum. [10] Out of these seven cases, five had a history of use of ventilation tubes (a proposed risk factor for otic infection due to mycobacteria).…”

Section: Discussionmentioning

confidence: 99%

“…[6] The fourth case occurred in an 8-year-old boy who was treated with isoniazid monotherapy (no susceptibility data were reported). [7] The fifth case, a 14-year-old girl with persistent otitis media, underwent mastoidectomy and was initially put on intravenous amikacin and clarithromycin.…”

Section: Discussionmentioning

confidence: 99%

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Mycobacterium fortuitum otitis media: Diagnostic and therapeutic dilemma

2012

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Tubercular otitis media is well reported in the scientific literature, but infections with atypical mycobacteria are poorly represented. Atypical mycobacteria are slowly emerging as a cause of various head and neck infections over the past few decades. Mycobacterium fortuitum is a rapidly growing, Group IV organism of Runyon's classification. Review of literature reveals only five otology cases affected by this organism. We report a case who responded very well with surgery and conventional antitubercular treatment.

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“…isoniazid and rifampicin). [4,6,7,10] Our case was similar to these cases as it was managed by antitubercular drugs with satisfactory results.…”

Section: Discussionsupporting

confidence: 77%

Section: Discussionmentioning

confidence: 99%

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Mycobacterium fortuitum otitis media: Diagnostic and therapeutic dilemma

2012

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“…Although rare, otologic infections with M. fortuitum in adults, associated with the use of topical steroid otic drops, have been reported (15,267). The largest single study in-volved 21 cases and occurred in the era prior to the era of routine testing and treatment with macrolides (117).…”

Section: Otitis Mediamentioning

confidence: 99%

Antimicrobial Susceptibility Testing, Drug Resistance Mechanisms, and Therapy of Infections with Nontuberculous Mycobacteria

2012

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SUMMARY Within the past 10 years, treatment and diagnostic guidelines for nontuberculous mycobacteria have been recommended by the American Thoracic Society (ATS) and the Infectious Diseases Society of America (IDSA). Moreover, the Clinical and Laboratory Standards Institute (CLSI) has published and recently (in 2011) updated recommendations including suggested antimicrobial and susceptibility breakpoints. The CLSI has also recommended the broth microdilution method as the gold standard for laboratories performing antimicrobial susceptibility testing of nontuberculous mycobacteria. This article reviews the laboratory, diagnostic, and treatment guidelines together with established and probable drug resistance mechanisms of the nontuberculous mycobacteria.

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“…Fourteen of the previously reported 89 cases included complete information regarding the following 15 parameters matching the present study: age, sex, occurrence of concomitant or previous ear disease, occurrence of other predisposing disease, time to diagnosis, symptoms at presentation, histopathology, type of bacteria, antibiotic treatment, length of therapy, spread of infection, radiological or intra-operative findings of bone destruction, surgical procedures, need for revision surgery, and sequelae 6 – 8 , 17 , 19 , 21 – 23 , 25 , 28 , 31 . Another 35 cases had 1 or 2 parameters missing 1 – 3 , 6 – 9 11 , 12 , 14 – 16 , 18 , 19 , 25 , 26 , 29 , 32 . In the remaining 23 reported sporadic cases and in the 17 patients infected from a single rinsing water source, 3 or more of the above parameters were missing 4 , 5 , 7 , 8 , 10 , 13 , 24 , 27 , 30 .…”

Section: Methodsmentioning

confidence: 99%