Mycobacterial infection in goats: Diagnosis and pathogenicity of the organism

Collins, P.; Davies, D.C.

doi:10.1016/0007-1935(84)90081-2

Cited by 4 publications

(2 citation statements)

References 8 publications

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“…However, nodular foci of caseous necrosis and calcification have been described, particularly in the mesenteric lymph nodes of goats ( Collins et al, 1984). There is some evidence that subspecies other than M. avium paratuberculosis , such as M. avium silvaticum , may be implicated in many caprine cases, possibly accounting for the particularly prominent focal tuberculous lesions ( Collins et al, 1984; Thorel et al, 1990).…”

Section: Discussionmentioning

confidence: 99%

The Pathology of Goat Paratuberculosis: Gross and Histopathological Lesions in the Intestines and Mesenteric Lymph Nodes

Khodakaram-Tafti

Rashidi

2000

Journal of Veterinary Medicine, Series B

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From a pathological examination of the intestinal tracts of 1590 goats killed at slaughterhouses in the Fars Province of Iran, 59 cases (3.71%) were suspected, on gross examination, of having paratuberculosis. The diagnosis was confirmed by histopathological study and Ziehl-Neelsen staining of direct smears of rectal faeces. On the basis of severity of involvement of the terminal ileum and mesenteric lymph nodes, the microscopic lesions were classified to mild, moderate and severe forms. Caseous necrosis and calcification were observed only in the mesenteric lymph nodes. High numbers of acid-fast organisms were present in the epithelioid macrophages of the intestine but were inapparent or sparse in the mesenteric lymph nodes. On microscopic examination, 13.5% of the suspected animals were found to have paratuberculosis, in comparison with 3.38% by direct faecal smears. In addition, 30.5% and 15.3% of the animals were diagnosed as having eosinophilic enteritis and linguatulosis, respectively. These findings stress the importance of a careful histopathological examination of the intestines and mesenteric lymph nodes for the diagnosis of paratuberculosis in goats.

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Section: Discussionmentioning

confidence: 99%

The Pathology of Goat Paratuberculosis: Gross and Histopathological Lesions in the Intestines and Mesenteric Lymph Nodes

Khodakaram-Tafti

Rashidi

2000

Journal of Veterinary Medicine, Series B

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“…During the subclinical stage of the disease, the pathogen is already shed into the environment, primarily with the feces. Starting intermittent shedding frequency as well as intensity increases with disease progression [ 1 , 2 , 3 ]. Studies also revealed an increasing likelihood of a lactogenic shedding of MAP in animals showing clinical symptoms [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

Analysis of Colostrum and Udder Skin Swabs from a Dairy Goat Herd in Germany regarding the Occurrence of Mycobacterium avium Subsp. paratuberculosis

Pickrodt

Donat

Moog³

et al. 2022

Animals

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Oral intake of Mycobacterium avium subspecies paratuberculosis (MAP) in first days of life is considered to be the main route of infection for paratuberculosis. This can be related to a direct contact to contaminated feces or feeding of MAP containing colostrum. Colostrum is believed to become contaminated either by lactogenic shedding or introduction of MAP from environmental sources. In this pilot study, the presence of MAP in individual and bulk colostrum samples from a paratuberculosis-infected, vaccinated dairy goat herd in Germany and the effect of udder skin disinfection on the MAP load of colostrum were examined. In order to distinguish between lactogenic shedding and fecal contamination, 49 udder skin swabs were cultivated on solid medium whereas 29 swabs were additionally analyzed by qPCR. qPCR was applied on 110 individual colostrum samples collected from 55 goats, one before and one after disinfection with a mycobactericidal disinfectant, and 14 bulk colostrum samples. MAP DNA was detected in 10.3% (3/29) of the swab samples, but no viable MAP was cultivated from any sample. These results indicate a low-level MAP contamination of the udder skin and colostrum of milking goats suggesting a low risk of MAP transmission via these routes.

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Experimental infection of calves with an apparently specific goat-pathogenic strain of Mycobacterium paratuberculosis

Saxegaard

1990

Journal of Comparative Pathology

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Mycobacterial infection in goats: Diagnosis and pathogenicity of the organism

Cited by 4 publications

References 8 publications

The Pathology of Goat Paratuberculosis: Gross and Histopathological Lesions in the Intestines and Mesenteric Lymph Nodes

The Pathology of Goat Paratuberculosis: Gross and Histopathological Lesions in the Intestines and Mesenteric Lymph Nodes

Analysis of Colostrum and Udder Skin Swabs from a Dairy Goat Herd in Germany regarding the Occurrence of Mycobacterium avium Subsp. paratuberculosis

Experimental infection of calves with an apparently specific goat-pathogenic strain of Mycobacterium paratuberculosis

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