1975
DOI: 10.1016/0027-5107(75)90235-3
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Mutagenicity of organophosphorus compounds in bacteria and drosophila

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Cited by 97 publications
(13 citation statements)
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“…It has also been used broadly as a fumigant against pests in a large number of stored products (8). The investigations on the toxicological evaluation of PMM indicated that it may have effects on nontarget living organisms such as fish, birds, and mammals, including humans (9)(10)(11)(12)(13)(14)(15).…”
Section: Introductionmentioning
confidence: 99%
“…It has also been used broadly as a fumigant against pests in a large number of stored products (8). The investigations on the toxicological evaluation of PMM indicated that it may have effects on nontarget living organisms such as fish, birds, and mammals, including humans (9)(10)(11)(12)(13)(14)(15).…”
Section: Introductionmentioning
confidence: 99%
“…Mutagenicity following storage was also noted by Hanna and Dyes (1975). In the fluctuation test trichlorfon was in a liquid médium for at least 72 h. This fact and the greater sensitivity of this assay compared with the Ames test allowed the detection of the mutagenic effect of trichlorfon at low concentrations.…”
Section: Discussionmentioning
confidence: 97%
“…More recently, 140 organophosphorus compounds were tested in E. coli WP2 and the results were compared with those obtained in Salmonella typhimurium and with the activity in Drosophila (vide infra) (Dyer and Hanna, 1973;Hanna and Dyer 1975). It was concluded that 20% of the compounds tested yielded positive mutagenic responses by producing base substitutions rather than frameshift mutations (Hanna and Dyer, 1975).…”
Section: Prokaryotesmentioning
confidence: 98%