Muskelphysiologie vom Standpunkt der kinetischen Theorie der Hochelastizität und der Entspannungshypothese des Kontraktionsmechanismus

Wöhlisch, Edgar

doi:10.1007/bf01734558

Cited by 38 publications

(3 citation statements)

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“…Does the hydrolysis of ATP occur during the contraction itself, or is contraction a spontaneous process, the actin and myosin being dissociated by ATP during relaxation? Does the tendency to shorten arise from the formation of new bonds in the shortened state ('internal energy' theories: Meyer, 1929;Buchthal & Kaiser, 1951;Polissar, 1952), or is it attributable to an increased freedom of the filaments to coil up under the influence of thermal agitation ('entropy theories' : Wohlisch, 1940;Pryor, 1950;Morales & Botts, 1952)?…”

Section: The Mechanism Of Contractionmentioning

confidence: 99%

Muscular contraction.

Huxley¹

1974

The Journal of Physiology

698

340

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Section: The Mechanism Of Contractionmentioning

confidence: 99%

Muscular contraction.

Huxley¹

1974

The Journal of Physiology

698

340

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“…The latter was not supposed to contain the commonly recognized antithrombin I11 activity. Certainly ether treatment destroys antithrombin (43), but this procedure does not necessarily get all of it out. In attempting to clarify the question of antithrombin IV, Seegers, Johnson, and Fell (44) decided that protein concentrates rich in factor VII tend to depress the rate of thrombin-inactivating activity.…”

Section: Antithrombin IVmentioning

confidence: 95%

Inactivation of Purified Autoprothrombin I With Antithrombin

Wh¹,

Schroeer²,

Kagami³

1964

Can. J. Biochem.

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Autoprothrombin I, was obtained by activating prothrombin preparations with autoprothrombin C. Autoprothrombin I, was obtained by activating prothrombin with the use of calcium ions and purified platelet factor 3. Both of these prothrombin derivatives were found to be inactivated by plasma and serum. Autoprothrombin I, was studied most extensively and was found to be inactivated by purified antithrombin. When antithrombin was first combined to capacity with purified thrombin the power to neutralize autoprothrombin I was almost eliminated. Autoprothrombin I1 was not destroyed by antithrombin and was found in serum as the main procoagulant. Most likely it is not in plasma.Autoprothrombin I,, autoprothrombin I,, autoprothrombi11 C, and thrombin all have reactive groups that combine with antithrombin. The activity in 1 n~g of purified autoprothrombin I, was neutralized by 50 ml plasma. One milligram of autoprothrombin C was neutralized by 5 ml plasma, and 7 ml plasma was sufficient to neutralize 1 mg of thrombin. Antithrombin IV is regarded as a kinetic effect and not as a substance. From a review of the literature it is concluded that there is no adequate evidence for appreciable quantities of factor VII in serum, or that it occurs in plasma independent of prothrombin.

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“…Rubber is derived from a biological material produced by plants. It contracts with the temperature [45] and heat engines based on rubber [46][47][48] are of interest since proteins such as collagen, fibroin and elastin contract in the same way [49][50][51]. More generally, almost any temperature-dependent material characteristic seems applicable in a heat engine.…”

Section: Simple Heat Enginesmentioning

confidence: 99%

Emergence of Animals from Heat Engines – Part 1. Before the Snowball Earths

Muller

2009

Entropy

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Abstract:The origin of life has previously been modeled by biological heat engines driven by thermal cycling, caused by suspension in convecting water. Here more complex heat engines are invoked to explain the origin of animals in the thermal gradient above a submarine hydrothermal vent. Thermal cycling by a filamentous protein 'thermotether' was the result of a temperature-gradient induced relaxation oscillation not impeded by the low Reynolds number of a small scale. During evolution a 'flagellar proton pump' emerged that resembled Feynman's ratchet and that turned into today's bacterial flagellar motor. An emerged 'flagellar computer' functioning as Turing machine implemented chemotaxis.

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Muskelphysiologie vom Standpunkt der kinetischen Theorie der Hochelastizität und der Entspannungshypothese des Kontraktionsmechanismus

Cited by 38 publications

References 0 publications

Muscular contraction.

Muscular contraction.

Inactivation of Purified Autoprothrombin I With Antithrombin

Emergence of Animals from Heat Engines – Part 1. Before the Snowball Earths

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