Muscle MRI STIR signal intensity and atrophy are correlated to focal lower limb neuropathy severity

Deroide, Nicolas; Bousson, Valérie; Mambre, L.; Vicaut, Éric; Laredo, J. D.; Kubis, Nathalie

doi:10.1007/s00330-014-3436-y

Cited by 8 publications

(5 citation statements)

References 26 publications

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“…79 Note that simple qualitative or semi-quantitative comparisons could lead to data misinterpretation, and thus, proper quantitation methods have to be applied to provide information about disease severity. 80…”

Section: Sodium Mrimentioning

confidence: 99%

Magnetic Resonance Imaging of the Musculoskeletal System at 7T

Juráš

Mlynárik

Szomolányi

et al. 2019

Topics in Magnetic Resonance Imaging

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In 2017, a whole-body 7T magnetic resonance imaging (MRI) device was given regulatory approval for clinical use in both the EU and United States for neuro and musculoskeletal applications. As 7 Tesla allows for higher signal-to-noise , which results in higher resolution images than those obtained on lower-field-strength scanners, it has attracted considerable attention from the musculoskeletal field, as evidenced by the increasing number of publications in the last decade. Besides morphological imaging, the quantitative MR methods, such as T 2 , T 2 ∗, T 1ρ mapping, sodium imaging, chemical-exchange saturation transfer, and spectroscopy, substantially benefit from ultrahigh field scanning. In this review, we provide technical considerations for the individual techniques and an overview of (mostly) clinical applications for the assessment of cartilage, tendon, meniscus, and muscle. The first part of the review is dedicated to morphological applications at 7T, and the second part describes the most recent developments in quantitative MRI at 7T.

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Section: Sodium Mrimentioning

confidence: 99%

Magnetic Resonance Imaging of the Musculoskeletal System at 7T

Juráš

Mlynárik

Szomolányi

et al. 2019

Topics in Magnetic Resonance Imaging

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“…In a study by Deroide et al, which investigated patients with neuropathic conditions, the EMG at baseline and during a MVC were weakly but significantly correlated to the MRC score [44]. Considering that a possible association between EMG and muscular force may help in the assessment of various aspects of muscle physiology, the addition of sEMG measurements for the evaluation of changes in muscle function following an intervention could support the interpretation of the MRC scale scores.…”

Section: Discussionmentioning

confidence: 99%

Does the Score on the MRC Strength Scale Reflect Instrumented Measures of Maximal Torque and Muscle Activity in Post-Stroke Survivors?

Kiper

Rimini

Falla

et al. 2021

Sensors

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It remains unknown whether variation of scores on the Medical Research Council (MRC) scale for muscle strength is associated with operator-independent techniques: dynamometry and surface electromyography (sEMG). This study aimed to evaluate whether the scores of the MRC strength scale are associated with instrumented measures of torque and muscle activity in post-stroke survivors with severe hemiparesis both before and after an intervention. Patients affected by a first ischemic or hemorrhagic stroke within 6 months before enrollment and with complete paresis were included in the study. The pre- and post-treatment assessments included the MRC strength scale, sEMG, and dynamometry assessment of the triceps brachii (TB) and biceps brachii (BB) as measures of maximal elbow extension and flexion torque, respectively. Proprioceptive-based training was used as a treatment model, which consisted of multidirectional exercises with verbal feedback. Each treatment session lasted 1 h/day, 5 days a week for a total 15 sessions. Nineteen individuals with stroke participated in the study. A significant correlation between outcome measures for the BB (MRC and sEMG p = 0.0177, ρ = 0.601; MRC and torque p = 0.0001, ρ = 0.867) and TB (MRC and sEMG p = 0.0026, ρ = 0.717; MRC and torque p = 0.0001, ρ = 0.873) were observed post intervention. Regression models revealed a relationship between the MRC score and sEMG and torque measures for both the TB and BB. The results confirmed that variation on the MRC strength scale is associated with variation in sEMG and torque measures, especially post intervention. The regression model showed a causal relationship between MRC scale scores, sEMG, and torque assessments.

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“…Mientras que la EMG tiene un rol fundamental en el diagnóstico de la neuropatía ciática, el estudio imagenológico surge como una herramienta que permite determinar su etiología y extensión, identificando por ejemplo, un tumor extrínseco, aneurisma o absceso. La RM permite el estudio de la neuropatía ciática, con una buena resolución de tejidos blandos y ausencia de irradiación 22,23 . La RM muscular que se realizó en dos casos, mostró cambios degenerativos con un patrón largo dependiente (mayor compromiso mientras más distal es el músculo) en ambos territorios (tibial y peroneo), destacando nuevamente la mayor severidad en los dependientes del nervio peroneo.…”

Section: Discussionunclassified

“…La RM muscular que se realizó en dos casos, mostró cambios degenerativos con un patrón largo dependiente (mayor compromiso mientras más distal es el músculo) en ambos territorios (tibial y peroneo), destacando nuevamente la mayor severidad en los dependientes del nervio peroneo. La RM, ha sido utilizada tanto en investigación preclínica en ratones 24 como en seres humanos, como un método para evaluar e incluso cuantificar el compromiso muscular 23 por denervación en neuropatías focales 22 (incluyendo neuropatía ciática) y en polineuropatías hereditarias 23 . Sin embargo, su uso clínico todavía es limitado.…”

Section: Discussionunclassified

Neuropatía ciática en pediatría: presentación clínica y seguimiento a largo plazo

et al. 2020

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La neuropatía ciática es una entidad infrecuente y de difícil diagnóstico en Pediatría. Su evolución a largo plazo no ha sido claramente definida.Objetivo: Analizar la presentación clínica y evolución de un grupo de niños con neuropatía ciática.Pacientes y Método: Análisis retrospectivo de las características clínicas de pacientes pediátricos con neuropatía ciática atendidos en 2 hospitales de Santiago, entre 2014-2018. Se evaluó examen motor, trofismo muscular, reflejos osteotendíneos, marcha, sensibilidad y dolor. Se estudió neuroconducción de nervio ciático, electromiografía (EMG) y en 3 pacientes, Resonancia Magnética (RM).Resultados: Se incluyeron 6 pacientes, edad promedio 11,8 años. Hubo 2 causas traumáticas, 2 compresivas, 1 vascular y 1 tumoral. Los 6 pacientes debutaron con pie caído e hiporreflexia/arreflexia aquiliana; 5 pacientes presentaron dolor neuropático severo. La EMG mostró en todos los casos compromiso en nervios y musculatura dependientes del nervio ciático. En 2 casos se realizó RM de cintura pélvica y extremidades inferiores, mostrando compromiso muscular selectivo en pierna en territorio ciático. En 1 caso, se realizó RM de plexo lumbosacro, y luego estudio histológico, que concluyeron un tumor neural benigno. En los 3 pacientes que tuvieron seguimiento mayor a un año, se observaron secuelas motoras, con marcha alterada.Conclusión: La neuropatía ciática en este grupo fue secundaria a diversas etiologías, predominando las traumático-compresivas. En los 3 casos que tuvieron seguimiento a largo plazo se observaron secuelas motoras significativas. En la mayoría la lesión se asoció a causas prevenibles como accidentes y posicionamiento en niños con compromiso de conciencia, lo que resulta fundamental en la prevención de una patología con alto grado de secuelas.

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Muscle MRI STIR signal intensity and atrophy are correlated to focal lower limb neuropathy severity

Cited by 8 publications

References 26 publications

Magnetic Resonance Imaging of the Musculoskeletal System at 7T

Magnetic Resonance Imaging of the Musculoskeletal System at 7T

Does the Score on the MRC Strength Scale Reflect Instrumented Measures of Maximal Torque and Muscle Activity in Post-Stroke Survivors?

Neuropatía ciática en pediatría: presentación clínica y seguimiento a largo plazo

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