Does the Score on the MRC Strength Scale Reflect Instrumented Measures of Maximal Torque and Muscle Activity in Post-Stroke Survivors?

Kiper, Paweł; Rimini, Daniele; Falla, Deborah; Baba, Alfonc; Rutkowski, Sebastian; Maistrello, Lorenza; Turolla, Andrea

doi:10.3390/s21248175

Cited by 8 publications

(5 citation statements)

References 49 publications

(54 reference statements)

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“…The days of ventilator use, ICU treatment time, and LOS of the subjects were recorded Activity function. We assessed patients' activity function with the Barthel Index (BI; score range: 0-100), ICU Mobility Scale (IMS; score range: 0-10), and Medical Research Council (MRC) Scale (score range: 0-60) [ 16 – 18 ], with the scores of all the three measures in direct proportion to the subjects' ability of daily living, mobility, and muscle strength, respectively QoL. We used the World Health Organization Quality of Life Assessment (100-item version) (WHOQOL-100) [ 19 ] to assess the QoL of the research participants from the physiological, mental, and environmental fields as well as the total QoL score.…”

Section: Methodsmentioning

confidence: 99%

“…Activity function. We assessed patients' activity function with the Barthel Index (BI; score range: 0-100), ICU Mobility Scale (IMS; score range: 0-10), and Medical Research Council (MRC) Scale (score range: 0-60) [ 16 – 18 ], with the scores of all the three measures in direct proportion to the subjects' ability of daily living, mobility, and muscle strength, respectively…”

Section: Methodsmentioning

confidence: 99%

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Influence of Early Multidisciplinary Collaboration on Prevention of ICU-Acquired Weakness in Critically Ill Patients

Wang

Tian

et al. 2022

Disease Markers

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Objective. This study focused on elucidating the influence of early multidisciplinary collaboration on preventing intensive care unit- (ICU-) acquired weakness (AW) in critically ill patients (CIPs). Methods. Ninety-five CIPs admitted between December 2018 and December 2021 were selected and assigned to the following two groups according to the intervention pattern: the control group (the Con; n = 40 ) treated with routine early rehabilitation intervention, and the research group (the Res; n = 55 ) intervened by early multidisciplinary collaborative intervention. The incidence of complications (ICU-AW, deep vein thrombosis (DVT), and pressure ulcers (PSs)) and recovery indices (days of ventilator use, ICU treatment time, and length of hospital stay (LOS)) were recorded. Besides, patients’ activity function and quality of life (QoL) were evaluated and compared, among which the former was evaluated by the Barthel Index (BI), ICU Mobility Scale (IMS), and Medical Research Council (MRC) Scale, and the latter was assessed by the World Health Organization Quality of Life Assessment (100-item version) (WHOQOL-100). Results. The data identified statistically a lower incidence of complications (ICU-AW, DVT, and PSs) and shorter time of ventilator use, ICU residence, and LOS in the Res compared with the Con. In addition, BI, IMS, MRC, and WHOQOL-100 scores in the Res elevated statistically after treatment and were higher than those of the Con. Conclusions. Early multidisciplinary collaboration can validly prevent ICU-AW in CIPs, reduce the incidence of DVT and PSs, and promote patients’ rehabilitation, mobility, and QoL.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Influence of Early Multidisciplinary Collaboration on Prevention of ICU-Acquired Weakness in Critically Ill Patients

Wang

Tian

et al. 2022

Disease Markers

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“…Lower limb muscle strength testing, where a grading of 0–5 reflects the maximum force executed by a certain muscle [ 40 , 41 ], will be conducted. Lower limb muscle strength is associated with gait recovery, and a grade ≥3 represents a predictor of independent walking after stroke [ 40 ].…”

Section: Methodsmentioning

confidence: 99%

Randomized Controlled Trial of Robot-Assisted Gait Training versus Therapist-Assisted Treadmill Gait Training as Add-on Therapy in Early Subacute Stroke Patients: The GAITFAST Study Protocol

et al. 2022

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The GAITFAST study (gait recovery in patients after acute ischemic stroke) aims to compare the effects of treadmill-based robot-assisted gait training (RTGT) and therapist-assisted treadmill gait training (TTGT) added to conventional physical therapy in first-ever ischemic stroke patients. GAITFAST (Clinicaltrials.gov identifier: NCT04824482) was designed as a single-blind single-center prospective randomized clinical trial with two parallel groups and a primary endpoint of gait speed recovery up to 6 months after ischemic stroke. A total of 120 eligible and enrolled participants will be randomly allocated (1:1) in TTGT or RTGT. All enrolled patients will undergo a 2-week intensive inpatient rehabilitation including TTGT or RTGT followed by four clinical assessments (at the beginning of inpatient rehabilitation 8–15 days after stroke onset, after 2 weeks, and 3 and 6 months after the first assessment). Every clinical assessment will include the assessment of gait speed and walking dependency, fMRI activation measures, neurological and sensorimotor impairments, and gait biomechanics. In a random selection (1:2) of the 120 enrolled patients, multimodal magnetic resonance imaging (MRI) data will be acquired and analyzed. This study will provide insight into the mechanisms behind poststroke gait behavioral changes resulting from intensive rehabilitation including assisted gait training (RTGT or TTGT) in early subacute IS patients.

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“…The cardiovascular examination revealed no abnormalities, and in the neurology examination, except for lower limb paralysis, no significant abnormality was evident. Based on the Medical Research Council (MRC) scoring scale, 10 his lower limbs strength was 1/5 (flicker or trace contraction) bilaterally and in the proximal and distal parts, while his upper limbs strength was 3/5 (active movement against gravity but not resistance) in both proximal and distal parts. He was not able to move his lower limbs actively and was unable to move his hands against resistance.…”

Section: Case Presentationmentioning

confidence: 99%

Hypokalemic paralysis following intramuscular betamethasone injection: A case report and review of literature

Ebrahimi,

Taheri,

Mousavinejad

et al. 2024

Clinical Case Reports

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Key Clinical MessageAcute neuromuscular paralysis is a relatively common condition in emergency rooms (ERs). They can be caused by several reasons, including adverse drug reactions. Betamethasone is a glucocorticoid commonly used for various conditions, such as allergic conditions. One of the rare but known side effects of glucocorticoids is hypokalemia. Rare cases of hypokalemia following high‐ and low‐dose glucocorticoid injections have been reported. This study presents the history of a young, healthy male without significant past medical history who presented with an inability to stand and walk due to four‐limb paralysis (more prominent in the lower limbs) following an intramuscular injection of a 4 mg betamethasone, which was prescribed for the treatment of allergic rhinitis. The patient was stabilized with an intravascular injection of potassium chloride diluted in 1000 mL of normal saline and monitored for 24 h, ruling out any other endocrine condition. Hypokalemia and its severe form are defined as the serum level of lower than 3.5 and 2.5 mEq/Lit, respectively. One of the etiologies of drug‐induced hypokalemic paralysis is systemic glucocorticoid administration. In severe cases, it can cause quadriplegia and other neuromuscular, respiratory, and cardiac complications. Therefore, it is an urgent condition that should be managed carefully. Pregnant women who are receiving these medications are a specific group at risk of hypokalemic paralysis. There are several safer treatments for seasonal allergic rhinitis compared to systemic glucocorticoids, which should be considered by physicians. Moreover, paralysis in patients receiving these medications should be approached attentively since it might be caused by hypokalemia, which can be life threatening if not treated. It is advisable that the blood level of electrolytes, especially potassium, be checked for patients who present with paralysis or weakness after glucocorticoid injections.

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Does the Score on the MRC Strength Scale Reflect Instrumented Measures of Maximal Torque and Muscle Activity in Post-Stroke Survivors?

Cited by 8 publications

References 49 publications

Influence of Early Multidisciplinary Collaboration on Prevention of ICU-Acquired Weakness in Critically Ill Patients

Influence of Early Multidisciplinary Collaboration on Prevention of ICU-Acquired Weakness in Critically Ill Patients

Randomized Controlled Trial of Robot-Assisted Gait Training versus Therapist-Assisted Treadmill Gait Training as Add-on Therapy in Early Subacute Stroke Patients: The GAITFAST Study Protocol

Hypokalemic paralysis following intramuscular betamethasone injection: A case report and review of literature

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