Muscle fiber velocity and electromyographic signs of fatigue in fibromyalgia

Klaver-Krol, E.G.; Rasker, Johannes J.; Henriquez, Nizare R.; Verheijen, Wilma G; Zwarts, Machiel J.

doi:10.1002/mus.23382

Cited by 13 publications

(10 citation statements)

References 38 publications

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“…Accordingly, FMS patients exhibited greater electromyographic signs of fatigue during sustained contraction of the trapezius muscle [519] or the quadriceps muscle [510]. Somewhat paradoxically, however, several other investigations revealed decreased electromyographic signs of fatigue in FMS patients compared to controls during voluntary contractions of the biceps brachii muscle [520,521], deltoid muscle [522], and the vastus medialis muscle [523]. The interpretations of these findings differ substantially.…”

Section: Muscle Fatiguementioning

confidence: 74%

“…Others consider their results consistent with abnormalities in the muscle membrane [521], possibly arising from the reported inability of FMS muscles to relax between contractions [524]. This is thought to result in long-lasting depolarization and hyperexcitability, which would then override the electromyographic signs of fatigue [521]. Alternatively, the discrepancy between the patients' higher perceived level of muscle fatigue and lower objective signs of fatigue has been interpreted as a central nervous dysfunction [522].…”

Section: Muscle Fatiguementioning

confidence: 88%

“…Some think that fewer objective signs of muscle fatigue in FMS patients reflect an altered muscle fiber composition and, therefore, a peripheral phenomenon [523], although no abnormalities in the distribution of type I and type II fibers have been detected in biopsy samples [490,492]. Others consider their results consistent with abnormalities in the muscle membrane [521], possibly arising from the reported inability of FMS muscles to relax between contractions [524]. This is thought to result in long-lasting depolarization and hyperexcitability, which would then override the electromyographic signs of fatigue [521].…”

Section: Muscle Fatiguementioning

confidence: 88%

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Fibromyalgia: A Critical and Comprehensive Review

Borchers

Gershwin

2015

Clinic Rev Allerg Immunol

226

217

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Fibromyalgia is a disorder that is part of a spectrum of syndromes that lack precise classification. It is often considered as part of the global overview of functional somatic syndromes that are otherwise medically unexplained or part of a somatization disorder. Patients with fibromyalgia share symptoms with other functional somatic problems, including issues of myalgias, arthralgias, fatigue and sleep disturbances. Indeed, there is often diagnostic and classification overlap for the case definitions of a variety of somatization disorders. Fibromyalgia, however, is a critically important syndrome for physicians and scientists to be aware of. Patients should be taken very seriously and provided optimal care. Although inflammatory, infectious, and autoimmune disorders have all been ascribed to be etiological events in the development of fibromyalgia, there is very little data to support such a thesis. Many of these disorders are associated with depression and anxiety and may even be part of what has been sometimes called affected spectrum disorders. There is no evidence that physical trauma, i.e., automobile accidents, is associated with the development or exacerbation of fibromyalgia. Treatment should be placed on education, patient support, physical therapy, nutrition, and exercise, including the use of drugs that are approved for the treatment of fibromyalgia. Treatment should not include opiates and patients should not become poly pharmacies in which the treatment itself can lead to significant morbidities. Patients with fibromyalgia are living and not dying of this disorder and positive outlooks and family support are key elements in the management of patients.

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Section: Muscle Fatiguementioning

confidence: 74%

Section: Muscle Fatiguementioning

confidence: 88%

Section: Muscle Fatiguementioning

confidence: 88%

See 1 more Smart Citation

Fibromyalgia: A Critical and Comprehensive Review

Borchers

Gershwin

2015

Clinic Rev Allerg Immunol

226

217

View full text Add to dashboard Cite

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“…Although somewhat controversial, the pathophysiological causes of the reduction in muscle strength should be sought in alterations of the muscle fibres themselves 44 , or in vasomotor dysregulation 45 , or in problems of energy metabolism and the regulation of growth factors 46 . Electrophysiological studies have also been conducted revealing the presence of functional alterations of the muscle membrane responsible for fatigue 47 .…”

Section: Discussionmentioning

confidence: 99%

Force-time curve features of handgrip strength in fibromyalgia syndrome

Salaffi

Farah

Carlo

2020

Sci Rep

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The aim of this study was to compare the handgrip strength (HGs), assessed with a cylindrical-shape grip device, of fibromyalgia syndrome (FM) patients with healthy subjects and to demonstrate the relationship between HGs characteristics and disease severity. Consecutive female patients with FM were enrolled and compared to a group of healthy women. The correlations between HGs curve characteristics and disease severity indices were studied through the Spearman's rho correlation coefficients (rho). The HGs threshold distinguishing the FM presence was determined using the receiver operating characteristic (ROC) curves analysis. Multivariate regression analysis was used in order to assess the contribution of covariates on the HGs. 110 patients (mean age 53.8 ± 12.4 years) and 111 healthy controls have been enrolled. Altogether all parameters related to the analysis of HGs were worse in patients with FM. The HGs cut-off distinguishing the presence of a FM was 14.2 Kg. A negative correlation was found between disease severity indices and peak force (p < 0.001). Factors significantly associated with HGs area under the curve (AUC) in multivariate analysis were the Widespread Pain Index (WPI) (p = 0.003) and the revised Fibromyalgia Impact Questionnaire (FIQR) (p = 0.016). HGs is reduced in female FM patients and is inversely related to disease severity. The force-time curves analysis may be used as a complementary tool in the FM assessment and monitoring.Fibromyalgia syndrome (FM) is a multi-symptom disorder, characterized mainly by chronic widespread musculoskeletal pain, chronic fatigue, sleep disturbance, symptoms of cognitive impairment, and activity limitations, the etiology of which is still to be clarified 1 .The physical fitness is globally reduced over the course of FM and under this term are included multiple domains, in particular muscle strength, aerobic activity, balance and flexibility: the limitations of one or more of these aspects determine a functional limitation 2,3 . Adequate muscle strength is obviously necessary to perform all the usual actions of daily life 4-6 . In female patients with FM, a strength deficit of 20% to 36% is documented compared to healthy women 7 . The reduction in muscle strength in women with FM results in a deterioration in the quality of life (QoL) 8 .Handgrip strength (HGs), as a substitute for overall muscle strength, is related to physical fitness 9,10 . HGs is traditionally measured as the maximum force that can be generated by each hand. This parameter is used to assess the degree of hand deterioration in the FM. However, peak force measurement alone does not take into account other hand strength characteristics such as force generation speed, sustainability, and grip force variability.A more accurate description of HGs is certainly provided by the force-time (FeT) curve analysis. The FeT curve can be used to assess effort sincerity and distinguish between sincere effort and false weakness 11 . Through the analysis of the FeT curve it is possible to reveal peak force, m...

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“…Em estudo de revisão bibliográfica sobre a morfologia muscular de indivíduos com síndrome da fibromialgia verificou-se presença de isquemia e/ou alterações metabólicas (SIMMS, GOLDENBERG, 1988;OKIFUJI et al, 1997), com a diminuição do fluxo sanguíneo, predispondo à diminuição do oxigênio nas fibras musculares, ocasionando anormalidade no metabolismo celular, como ocorre em níveis mais baixos de adenosina-trifosfato (ATP), que resulta em dor muscular durante a realização de atividades (OLSEN, PARK, 1998). Outros autores compartilharam dessa hipótese etiológica associando a utilização de eletromiografia de superfície para investigar essa condição (ELERT et al, 2001;HÄKKINEN et al, 2002;MARQUES et al, 2002;KLAVER-KRÓL et al, 2007;GERDLE et al, 2008;BAZZICHI et al, 2009;CASALE et al, 2009;NASSIRI et al, 2009;FALLA et al, 2010;GERDLE et al, 2010;MAQUET et al, 2010;CASALE, RAINOLDI, 2011;KLAVER-KRÓL et al, 2012).…”

Section: Segundo Os Critérios Estabelecidos Pelo Comitê Do American Cunclassified

O impacto da síndrome da fibromialgia na musculatura mastigatória e cervical: análise eletromiográfica, ultrassonográfica, força de mordida e eficiência mastigatória

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Minha orientadora Profa. Dra. Simone Cecilio Hallak Regalo Fantástica orientadora, pessoa com uma energia contagiante! Agraciada com sabedoria, inteligência, carisma, profissionalismo e humildade. Obrigado por acreditar em mim, pelo carinho, paciência e temperança empregados no momento mais difícil que vivi até hoje. Obrigado por me defender, ensinar e me deixar fazer parte de seu ciclo de convivência.

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Muscle fiber velocity and electromyographic signs of fatigue in fibromyalgia

Abstract: In the patients with FM, we clearly showed functional abnormalities of the muscle membrane, which led to high conduction velocity and resistance to fatigue in electromyography.

Cited by 13 publications

References 38 publications

Fibromyalgia: A Critical and Comprehensive Review

Fibromyalgia: A Critical and Comprehensive Review

Force-time curve features of handgrip strength in fibromyalgia syndrome

O impacto da síndrome da fibromialgia na musculatura mastigatória e cervical: análise eletromiográfica, ultrassonográfica, força de mordida e eficiência mastigatória

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