Muscle Dystrophy of Carp Due to Oxidized Oil and the Preventive Effect of Vitamin E

Hashimoto, Yoshiro; Okaichi, Tomotoshi; Watanabe, Takeshi; Furukawa, Atushi; Umezu, Takeshi

doi:10.2331/suisan.32.64

Cited by 25 publications

(11 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Previous studies by Hung et al (1980), Stephan et al (1993), Hashimoto et al (1966) and Sakaguchi and Hamaguchi (1969) on rainbow trout (Oncorhynchus mykiss), seabass (Dicentrarchus labrax), common carp (Cyprinus carpio) and yellowtail (Seriola quinqueradiata), respectively, have demonstrated the effect of vitamin E supplementation in foods containing oxidized oils, in improving growth performance and tissue oxidative state. It should be noted that in all of these studies, a stable a-tocopherol ester (a-tocopheryl acetate) was employed, meaning that little or no protection was provided to the dietary oil, since the ester functions as an antioxidant only upon acid hydrolysis (as encountered in the gut).…”

Section: Introductionmentioning

confidence: 96%

Muscle and hepatic fatty acid profiles and α-tocopherol status in African catfish (Clarias gariepinus) given diets varying in oxidative state and vitamin E inclusion level

Baker

Davies

1997

Anim. Sci.

View full text Add to dashboard Cite

On termination of a 56-day feeding trial, the effect of dietary oxidized oil and all-rac-a-tocopheryl acetate on fatty acid and a-tocopherol status of juvenile African catfish (Clarias gariepinusj muscle and liver was investigated. Clarias of mean initial weight 15-8 (s.e. 0-29) g were given food at -proportionately 0-03 body weight per day on diets of two oxidative states (fresh or oxidized) at two levels of supplemental a-tocopheryl acetate (20 or 100 mg/kg dry matter). As well as having a significant detrimental effect on final body weight (P < 0-001), oxidation of the dietary lipid source was responsible for decreasing muscle but not hepatic polyunsaturated fatty acids (PUTAs). Liver tissue was suspected of actively synthesizing longer chain PUT As in response to consumption of oxidized oils, as indicated by decreases in the proportions of linoleate (18:2 n-6) and linolenate (18:3 n-3) and the increased abundance of eicosatetraenoic acid (20:4 n-6, arachidonate) and docosahexaenoic acid (22 : 6 n-3, DHA). This phenomenon has not been described in fish nutrition and therefore possible mechanisms are discussed. Additionally, oxidized oils in catfish diets caused significant depletion of a-tocopherol from both muscle and liver (P < 0-05). Modulation of the effects of oxidized lipids was achieved at the higher dietary tocopherol concentration. Appearance of an unknown aliphatic compound (equivalent chain length (ECL) = 13-1), believed to be a product of lipid peroxidation, demonstrated that catfish given rancid/low-tocopherol diets had been subjected to heightened oxidative nutritional stress. Values obtained for this peak were significantly correlated with dietary regime (P < 0-02), Once more, dietary a-tocopheryl acetate moderated this effect. It was concluded that elevated inclusion of all-rac-a-tocopheryl acetate into diets for African catfish could abrogate the effects of oxidized dietary lipids on muscle and liver fatty acids and a-tocopherol.

show abstract

Section: Introductionmentioning

confidence: 96%

Muscle and hepatic fatty acid profiles and α-tocopherol status in African catfish (Clarias gariepinus) given diets varying in oxidative state and vitamin E inclusion level

Baker

Davies

1997

Anim. Sci.

View full text Add to dashboard Cite

show abstract

“…Thus, from the present study, there appears to be a relationship between the presence of oxidized lipids in the diet and RTFS. This is hardly surprising insofar as others have noted deleterious changes in fish resulting from the consumption of diets with oxidized lipids ( Faktorovich 1959; Hashimoto, Okaishi, Watanabe & Furukama 1966; Moccia et al . 1984 ; Roald et al .…”

Section: Resultsmentioning

confidence: 95%

Influence of oxidized lipids in diets on the development of rainbow trout fry syndrome

Daskalov

Robertson

Austin

2000

Journal of Fish Diseases

View full text Add to dashboard Cite

Rainbow trout, Oncorhynchus mykiss (Walbaum), fry fed with a diet containing high levels of oxidized lipid, i.e. 46/128–54/164 meq kg−1 oil, fared less well than controls following challenge with Flavobacterium psychrophilum, the causative agent of rainbow trout fry syndrome (RTFS). In three experiments, a greater number of fish fed with the diet containing oxidized lipid died after challenge in comparison to the controls. Moreover, the pathogen was recovered as pure culture growth from the gills and kidney of dead fry. The use of diets rich in oxidized lipids led to dystrophic changes in the liver, kidney and muscle. In comparison, histopathological changes were not observed in fish fed control diets. Overall, a link was demonstrated between the presence of elevated levels of oxidized lipids in the diet and the development of RTFS.

show abstract

“…Many previous studies have shown that fish diseases showing thinning or atrophy of the body were because of myopathy of the lateral musculature, associated with vitamin E deficiency or intoxication of rancid oil in the diet (Hashimoto, Okaichi, Watanabe, Furukawa & Umezu 1966; Helder 1979; Kubota, Funahashi, Endo & Miyazaki 1980; Miyazaki & Kubota 1981a,b; Lovell, Miyazaki & Rabegnator 1984; Miyazaki 1986; Huerkamp, Ringler & Chrisp 1988; McLoughlin, Kennedy & Kennedy 1992; National Research Council 1993; Taveekijakarn, Miyazaki, Matsumoto & Aria 1996). Muscle myopathy in fish has also been associated with selenium deficiency and has been experimentally reproduced in fish fed diets that are low in or devoid of vitamin E or selenium, or on diets containing varying amounts of peroxidized fish oils (Murai & Andrews 1974; Poston, Combs & Leibovitz 1976; Smith 1979; Cowey, Degener, Tacon, Youngson & Bell 1984; Gatlin, Poe & Wilson 1986; Miyazaki 1986, 1995; Taveekijakarn et al.…”

Section: Vitamin E (α‐Tocopherol) Present In the Formulated Barramunmentioning

confidence: 99%

Lateral muscular myopathy associated with vitamin E deficiency in farmed barramundi, Lates calcarifer (Bloch)

Bowater

Burren²

2007

Journal of Fish Diseases

View full text Add to dashboard Cite

Muscle Dystrophy of Carp Due to Oxidized Oil and the Preventive Effect of Vitamin E

Cited by 25 publications

References 0 publications

Muscle and hepatic fatty acid profiles and α-tocopherol status in African catfish (Clarias gariepinus) given diets varying in oxidative state and vitamin E inclusion level

Muscle and hepatic fatty acid profiles and α-tocopherol status in African catfish (Clarias gariepinus) given diets varying in oxidative state and vitamin E inclusion level

Influence of oxidized lipids in diets on the development of rainbow trout fry syndrome

Lateral muscular myopathy associated with vitamin E deficiency in farmed barramundi, Lates calcarifer (Bloch)

Contact Info

Product

Resources

About