2021
DOI: 10.1007/s13206-021-00025-0
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Multistory Stairs-based, Fast and Point-of-care Testing for Disease Biomarker Using One-step Capillary Microfluidic Fluoroimmunoassay Chip via Continuous On-chip Labelling

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Cited by 13 publications
(6 citation statements)
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“…For example, a microfluidic chip model mimicking the blood–brain barrier, which is a biological barrier located in the vasculature of the human brain, has been fabricated [ 2 ], and a microfluidic organ-on-chip system has been constructed for the real-time monitoring of cellular metabolites [ 3 ]. Furthermore, it has been shown that microfluidic platforms can enable the development of organ-on-a-chip devices to study cancer metastasis [ 4 ] as well as diagnostic models to test for diseases [ 5 , 6 ] and screen for drugs [ 7 ]. The advantage of using a fluidic chip lies in the dimensional similarity of the microfluidic channel to human microenvironments, particularly human vasculature.…”
Section: Introductionmentioning
confidence: 99%
“…For example, a microfluidic chip model mimicking the blood–brain barrier, which is a biological barrier located in the vasculature of the human brain, has been fabricated [ 2 ], and a microfluidic organ-on-chip system has been constructed for the real-time monitoring of cellular metabolites [ 3 ]. Furthermore, it has been shown that microfluidic platforms can enable the development of organ-on-a-chip devices to study cancer metastasis [ 4 ] as well as diagnostic models to test for diseases [ 5 , 6 ] and screen for drugs [ 7 ]. The advantage of using a fluidic chip lies in the dimensional similarity of the microfluidic channel to human microenvironments, particularly human vasculature.…”
Section: Introductionmentioning
confidence: 99%
“…7 However, the potential application of PDMS in passive microfluidic devices is limited by its low surface energy, which makes it hydrophobic. 8,9…”
Section: Introductionmentioning
confidence: 99%
“…The sensitivity of redox cycling was compared to the TMB-based chromogenic detection, luminol-based chemiluminescence assay, and a commercial rapid test (lateral flow immunoassay). [15][16][17][18]…”
Section: Introductionmentioning
confidence: 99%