A vertically paired electrode for redox cycling and its application to immunoassays

Park, Jun‐Hee; Lee, Ga-Yeon; Song, Zhiquan; Bong, Ji-Hong; Kim, Hong Rae; Kang, Min‐Jung; Pyun, Jae Chul

doi:10.1039/d2an01648f

Cited by 4 publications

(1 citation statement)

References 53 publications

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“…The electrode gap should be as narrow as possible to facilitate the diffusion of the redox couple and enhance the redox cycling efficiency. To date, various electrode systems have been reported for redox cycling, including interdigitated array (IDA) electrodes [ 78 ], twin-electrode thin-layer cells [ 79 ], vertically paired electrodes [ 80 ], rotating ring-disc electrodes [ 81 ], and others [ 82 , 83 ].…”

Section: Types Of Redox Cycling Reactionsmentioning

confidence: 99%

Overview on the Development of Electrochemical Immunosensors by the Signal Amplification of Enzyme- or Nanozyme-Based Catalysis Plus Redox Cycling

Xia,

Gao,

Zhang

et al. 2024

Molecules

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Enzyme-linked electrochemical immunosensors have attracted considerable attention for the sensitive and selective detection of various targets in clinical diagnosis, food quality control, and environmental analysis. In order to improve the performances of conventional immunoassays, significant efforts have been made to couple enzyme-linked or nanozyme-based catalysis and redox cycling for signal amplification. The current review summarizes the recent advances in the development of enzyme- or nanozyme-based electrochemical immunosensors with redox cycling for signal amplification. The special features of redox cycling reactions and their synergistic functions in signal amplification are discussed. Additionally, the current challenges and future directions of enzyme- or nanozyme-based electrochemical immunosensors with redox cycling are addressed.

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