“…With the Verhoeff-Van Gieson stain, specific for elastic fibers, the content of these fibers is shown to be slightly reduced or absent. In transmission electron microscopy, no significant morphological changes are shown [ 2 - 3 , 5 ]. Dermatoscopy reveals white, homogeneous, circumscribed areas with thin dotted or short vessels, without follicular involvement [ 11 ].…”
Section: Discussionmentioning
confidence: 99%
“…The use of 1550-nm fractional non-ablative laser, Erbium-doped Yttrium aluminum garnet laser, and carbon dioxide (CO 2 ) laser have been reported. Other treatment options include photoprotection and topical preparations with retinoids [ 5 , 18 ] or antioxidants that reduce age-induced free radicals [ 19 ]. Tacrolimus 0.1% twice daily has demonstrated an improvement in pruritus [ 20 ].…”
White fibrous papulosis of the neck is a rare entity, with a benign course and unknown pathogenesis. It is clinically characterized by the appearance of firm, persistent, usually asymptomatic, non-follicular papules located on the neck. We present the case of a 72-year-old patient who presented pruritic lesions on the neck whose biopsy was compatible with this entity.
“…With the Verhoeff-Van Gieson stain, specific for elastic fibers, the content of these fibers is shown to be slightly reduced or absent. In transmission electron microscopy, no significant morphological changes are shown [ 2 - 3 , 5 ]. Dermatoscopy reveals white, homogeneous, circumscribed areas with thin dotted or short vessels, without follicular involvement [ 11 ].…”
Section: Discussionmentioning
confidence: 99%
“…The use of 1550-nm fractional non-ablative laser, Erbium-doped Yttrium aluminum garnet laser, and carbon dioxide (CO 2 ) laser have been reported. Other treatment options include photoprotection and topical preparations with retinoids [ 5 , 18 ] or antioxidants that reduce age-induced free radicals [ 19 ]. Tacrolimus 0.1% twice daily has demonstrated an improvement in pruritus [ 20 ].…”
White fibrous papulosis of the neck is a rare entity, with a benign course and unknown pathogenesis. It is clinically characterized by the appearance of firm, persistent, usually asymptomatic, non-follicular papules located on the neck. We present the case of a 72-year-old patient who presented pruritic lesions on the neck whose biopsy was compatible with this entity.
This chapter reviews acquired changes in dermal connective tissue during normal ageing and in disease processes, including photodamage. Corticosteroids are a potent cause of dermal atrophy, which may also be congenital or induced by inflammatory disorders related to morphoea. Enzymatic degradation of elastic tissue results in localised or generalised skin laxity, which resembles genetic disorders such as pseudoxanthoma elasticum and cutis laxa. In contrast, some disorders are characterised by excessive deposition of collagen or elastic tissue. Fibrosis is associated with contracture, which causes deformity and restricted movement as in palmoplantar fibromatosis. Several chemical environmental triggers induce diffuse fibrosis resembling systemic sclerosis. Keloids represent an abnormal scarring response to trauma. Finally, dermal connective tissue components may be extruded via the epidermis in perforating disorders such as elastosis perforans serpiginosa.
White fibrous papulosis of the neck (WFPN) is a variant of fibroelastolytic papulosis among with pseudoxanthoma elasticum-like papillary dermal elastolysis (PXE-PDE) and papillary dermal elastosis (PDE), which can be considered as an underdiagnosed and/or under reported condition. All the three variants clinically resemble each other, while the differentiation is histopathological. 1 Here, we present a case of sudden-onset WFPN on the neck of an elderly female patient, accompanied by the formation of eruptive milia cysts. A 78-year-old female patient presented with white papules on the posterior aspect of the neck that had been present for the past 3 months; however, she reported a sudden onset of the lesions. She did not have any associated symptoms. No family members reported How to cite this article: Aktaş Karabay E, Semiz Y, Singer R, Dobral A, Yalçın Ö. Sudden onset of white fibrous papulosis of the neck and milia cysts on the neck of an elderly female patient.
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