Multiple symmetric lipomatosis: clinical aspects and outcome in a long-term longitudinal study

Enzi, Giuliano; Busetto, Luca; Ceschin, Elena; Coin, Alessandra; Digito, Maura; Pigozzo, Sabrina

doi:10.1038/sj.ijo.0801867

Cited by 124 publications

(143 citation statements)

References 24 publications

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“…A simple 10 . In 1898, the disease was defined by Launois and Bensaude in a series of patients as a well-defined clinical entity and termed benign symmetric lipomatosis 8 .…”

Section: Case Reportmentioning

confidence: 99%

“…Enzi et al 8 classify MLS into 2 types. In type I MLS, the fat accumulations are limited, forming non encapsulated masses that are distributed symmetrically in the upper re gion of the body.…”

Section: Case Reportmentioning

confidence: 99%

“…Stopping alcohol con sumption is associated with a discrete regression of fat ac cumulation; meanwhile, increased alcohol consumption appears to accelerate lipoma growth 8 . Hyperuricemia, gout, liver disease, polyneuropathy, diabetes, and gluco se intole rance are occasionally identified in patients with MLS 6 ; however, some reports suggest that fat tissue accu mulation is metabolically unrelated and is not necessari ly accompanied by insulin resistance, possibly preventing li potoxicity 9 .…”

Section: Introductionmentioning

confidence: 99%

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Lipomatose simétrica múltipla

Sousa¹,

Fernandes²,

Rechtman³

2013

Rev. Bras. Cir. Plást.

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Multiple symmetric lipomatosis, also called Madelung's syndrome, is a rare disease charac terized by the accumulation of rapidly growing benign fat tissue, particularly in the cervical region, back, and more rarely in the extremities and face. It is generally associated with chronic alcoholism. Surgical treatment is palliative, and relapse is common. This paper reports the case of a patient with multiple symmetric lipomatosis followed by a review of the literature addressing the diagnosis and treatment of this condition.Keywords: Multiple symmetrical lipomatosis. Lipomatosis. Adipose tissue/pathology. RESUMOA lipomatose simétrica múltipla ou síndrome de Madelung é uma doença rara, caracterizada por depósitos de tecido adiposo de caráter benigno, de rápido crescimento, principalmente em região cervical, dorso e, mais raramente, membros e face, em geral relacionados ao al coolismo crônico. O tratamento cirúrgico é paliativo e a recidiva é comum. Neste trabalho é relatado um caso de paciente portador de lipomatose simétrica múltipla, seguido de revisão de literatura enfocando diagnóstico e tratamento dessa afecção.Descritores: Lipomatose simétrica múltipla. Lipomatose. Tecido adiposo/patologia.

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“…A simple 10 . In 1898, the disease was defined by Launois and Bensaude in a series of patients as a well-defined clinical entity and termed benign symmetric lipomatosis 8 .…”

Section: Case Reportmentioning

confidence: 99%

Section: Case Reportmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Lipomatose simétrica múltipla

Sousa¹,

Fernandes²,

Rechtman³

2013

Rev. Bras. Cir. Plást.

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show abstract

“…A lipomatose é associada com hipertensão arterial, anemia macrocítica, dano hepático associado ao álcool, intolerância a glicose, diabetes mellitus, hiperlipoproteinemia, hipertrigliceridemia, colesterol total e HDL normal ou aumentado, hiperuricemia, acidose tubular renal, tumores malignos das vias aéreas superiores, esteatose hepática, cirrose, polineuropatia periférica 7 .…”

Section: Introdução Introdução Introdução Introdução Introduçãounclassified

“…Abstinência de álcool é uma medida não cirúrgica a ser implementada durante o acompanhamento destes pacientes 5 .…”

Section: Introdução Introdução Introdução Introdução Introduçãounclassified