Multiple Sklerose

Peters, Gerd

doi:10.1007/978-3-642-94735-3_16

Cited by 6 publications

(2 citation statements)

References 154 publications

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“…In fact, for a number of years, the misconception that these CNS structures are ‘spared’ in MS abounded in scientific circles. A report in German,57 and a fleeting reference to unpublished observations of olfactory bulb/tract pathology in MS,56 certainly did not help dispel this belief.…”

Section: Olfactory Dysfunction In Cns Demyelinating Diseasesmentioning

confidence: 99%

Back on the scent: the olfactory system in CNS demyelinating diseases

Joseph

DeLuca

2016

J Neurol Neurosurg Psychiatry

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Olfactory dysfunction is recognised across an ever broadening spectrum of neuropsychiatric conditions including central nervous system (CNS) demyelinating diseases such as multiple sclerosis (MS) and neuromyelitis optica (NMO). In this review, we unravel the striking evidence highlighting how olfactory loss is a common clinical feature in MS and NMO. We provide an overview of the supportive psychophysical, electrophysiological, radiological and pathological data that point to the anatomical substrate of olfactory deficits in these diseases. The pattern of underlying pathology affecting the olfactory system is shown to be complex, involving multiple structures that are affected in different ways throughout the course of the disease. This review is the first to synthesise the expanding body of literature on the topic, provides novel insight into the way in which the olfactory system is affected in CNS demyelinating diseases, and raises intriguing questions about the role of this system in the pathogenesis of these diseases.

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Section: Olfactory Dysfunction In Cns Demyelinating Diseasesmentioning

confidence: 99%

Back on the scent: the olfactory system in CNS demyelinating diseases

Joseph

DeLuca

2016

J Neurol Neurosurg Psychiatry

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“…• 1S − 3S transition at LKB and MPQ [35,36]: The 2010 results from the LKB group delivered the second most precise transition frequency measurement in H with a total uncertainty of 13 kHz corresponding to a relative accuracy of 4.5 × 10 −12 . The error budget was dominated by statistics (12 kHz) and uncertainties in the velocity distribution of the atomic beam (3 kHz).…”

Section: Hydrogen Experimentsmentioning

confidence: 99%

Experiments towards resolving the proton charge radius puzzle

Antognini

Schuhmann

Amaro

et al. 2016

EPJ Web of Conferences

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Abstract.We review the status of the proton charge radius puzzle. Emphasis is given to the various experiments initiated to resolve the conflict between the muonic hydrogen results and the results from scattering and regular hydrogen spectroscopy. The proton charge radius puzzleThe historical route to the proton charge radius (r p ) is from elastic electron-proton scattering. In a completely complementary fashion, it has been obtained also from "high-precision" laser spectroscopy of hydrogen (H). Since a few years, "high-sensitivity" laser spectroscopy of muonic hydrogen (μp) offers a third way. The value extracted from μp with a relative accuracy of 5×10 −4 is an order of magnitude more accurate than obtained from the other methods. Yet the value is 4% smaller than derived from electron-proton scattering and H spectroscopy with a disagreement at the 7σ level [1][2][3][4][5].In the last five years as summarized in [6,7] various cross checks and refinements of boundstate QED calculations needed for the extraction of r p from μp have been performed, together with investigations of the proton structure. Several suggestions in the field of "beyond standard model" BSM physics have been articulated, re-analysis of scattering data have been carried out and new experiments have been initiated. Despite this, presently the discrepancy still persists and the resolution a

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Entzündliche Erkrankungen des Zentralnervensystems

Solcher¹

1988

Pathologie Des Nervensystems III

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Multiple Sklerose

Cited by 6 publications

References 154 publications

Back on the scent: the olfactory system in CNS demyelinating diseases

Back on the scent: the olfactory system in CNS demyelinating diseases

Experiments towards resolving the proton charge radius puzzle

Entzündliche Erkrankungen des Zentralnervensystems

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