Multiple screening of medicinal plants from Oaxaca, Mexico: ethnobotany and bioassays as a basis for phytochemical investigation

Frei, Barbara; Heinrich, Michael; Bork, Peter M.; Herrmann, Dieter B.; Jaki, Birgit U.; Kato, Takeshi; Kuhnt, Michaela; Schmitt, J.; Schühly, Wolfgang; Volken, C.; Sticher, Otto

doi:10.1016/s0944-7113(98)80025-1

Cited by 26 publications

(20 citation statements)

References 23 publications

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“…The superior antibacterial activity of T. zebrina compared to the other tested species may be attributed to its exceptionally high phenolic and tannin content. The superior antioxidant and antibacterial activity of T. zebrina compared to the other Commelinaceae may explain several of its ethnopharmalogical applications, particularly its anti-inflammatory and anti-infective activity [ 43 , 44 ]. Surprisingly, T. pallida was similarly active against Gram-negative bacteria (MIC of 5 mg/mL against the same two Gram-negative strains) despite having the lowest antioxidant content and activity.…”

Section: Resultsmentioning

confidence: 99%

Antioxidant Content, Antioxidant Activity, and Antibacterial Activity of Five Plants from the Commelinaceae Family

Tan

Yap²,

Tan³

et al. 2014

Antioxidants

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Commelinaceae is a family of herbaceous flowering plants with many species used in ethnobotany, particularly in South America. However, thus far reports of their bioactivity are few and far between. The primary aim of this study was to quantify the antioxidant and antibacterial activity of five Commelinaceae methanolic leaf extracts. The antioxidant content was evaluated by the total phenolic content (TPC), total tannin content (TTC), and total flavonoid content (TFC) assays. The antioxidant activities measured were DPPH free radical scavenging (FRS), ferric reducing power (FRP), and ferrous ion chelating (FIC); of the five plants, the methanolic leaf extract of Tradescantia zebrina showed the highest antioxidant content and activity, and exhibited antibacterial activity against six species of Gram-positive and two species of Gram-negative bacteria in a range of 5–10 mg/mL based on the broth microdilution method.

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Section: Resultsmentioning

confidence: 99%

Antioxidant Content, Antioxidant Activity, and Antibacterial Activity of Five Plants from the Commelinaceae Family

Tan

Yap²,

Tan³

et al. 2014

Antioxidants

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“…Rob., Inula aurantiaca (L.) Spreng., and Tagetes punctate Sessé & Moc 1 . Antimicrobial activity from this plant has been reported against Micrococcus luteus , Bacillus cereus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Alternaria alternata , and Fusarium solani ; it is also reportedly innocuous toward cell lines such as KB (human nasopharyngeal carcinoma), Caco-2 (human colon carcinoma) and Bacillus liqueniformis ( Frei et al, 1998 ; Lira-De León et al, 2014 ). Aerial parts of this vegetable species are used among Zapotec Indians (healers, midwives, and herbalists) to cure the stomachache ( Frei et al, 1998 ).…”

Section: Introductionmentioning

confidence: 99%

“…Antimicrobial activity from this plant has been reported against Micrococcus luteus , Bacillus cereus, Staphylococcus epidermidis, Pseudomonas aeruginosa, Alternaria alternata , and Fusarium solani ; it is also reportedly innocuous toward cell lines such as KB (human nasopharyngeal carcinoma), Caco-2 (human colon carcinoma) and Bacillus liqueniformis ( Frei et al, 1998 ; Lira-De León et al, 2014 ). Aerial parts of this vegetable species are used among Zapotec Indians (healers, midwives, and herbalists) to cure the stomachache ( Frei et al, 1998 ). The bibliographic investigation carried out by Alonso-Castro et al (2011) in Mexico scientific books, local encyclopedias of the Mexican Institute for Indigenous Studies (INI), and scientific published material on native Mexican medicinal flora showed that A. aurantium is used in Mexico to treat gastrointestinal disorders as diarrhea, dysentery, and gastric ulcers.…”

Section: Introductionmentioning

confidence: 99%

Antiamoebic Activity of Adenophyllum aurantium (L.) Strother and Its Effect on the Actin Cytoskeleton of Entamoeba histolytica

et al. 2016

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In Mexico, the Adenophyllum aurantium (L.) Strother plant is consumed as an infusion to treat intestinal diseases such as amoebiasis, which is an endemic health problem in Mexico and other countries. However, the effect of A. aurantium on Entamoeba histolytica, the causative agent of amoebiasis, is unknown. An aerial part methanolic extract (AaMeA), a root methanolic extract (AaMeR) and a root ethyl acetate extract (AaEaR) were tested on E. histolytica trophozoites. AaMeA and AaMeR did not show antiproliferative activity; however, AaEaR exhibited an in vitro GI50 of 230 μg/ml, and it was able to inhibit the differentiation of Entamoeba invadens trophozoites into cysts. The intraperitoneal administration of AaEaR (2.5 or 5 mg) to hamsters that were infected with E. histolytica inhibited the development of amoebic liver abscesses in 48.5 or 89.0% of the animals, respectively. Adhesion to fibronectin and erythrophagocytosis were 28.7 and 37.5% inhibited by AaEaR, respectively. An ultrastructure analysis of AaEaR-treated trophozoites shows a decrease in the number of vacuoles but no apparent cell damage. Moreover, this extract affected the actin cytoskeleton structuration, and it prevented the formation of contractile rings by mechanism(s) that were independent of reactive oxygen species and RhoA activation pathways. 13C NMR data showed that the major compounds in the AaEaR extract are thiophenes. Our results suggest that AaEaR may be effective in treatments against amoebiasis, nevertheless, detailed toxicity studies on thiophenes, contained in AaEaR, are required to avoid misuse of this vegetal species.

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“…In Mexico, cultural and biological diversity form the basis of traditional medicine that helps support the health of the nation, largely through the use of over 5,000 species of medicinal plants. 10 Ortiz de Montellano, alongside others, argues that 'early Mesoamerica was a cultural unit sharing a common worldview, religion, and ideas of human physiology and health' . 11 he common cultural characteristics of pre-Columbian Mesoamerica include intensive agriculture, religion manifested in monumental architecture, developed art styles expressed in several media, urban centres, expansionist politics, social stratiication, specialization, markets and extensive trade, elaborate calendars, and hieroglyphic writing.…”

mentioning

confidence: 99%

How Can Ethnobotany Contribute to the History of Western Herbal Medicine? A Mesoamerican Answer

Waldstein

2014

Critical Approaches to the History of Western Herbal Medicine

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Multiple screening of medicinal plants from Oaxaca, Mexico: ethnobotany and bioassays as a basis for phytochemical investigation

Cited by 26 publications

References 23 publications

Antioxidant Content, Antioxidant Activity, and Antibacterial Activity of Five Plants from the Commelinaceae Family

Antioxidant Content, Antioxidant Activity, and Antibacterial Activity of Five Plants from the Commelinaceae Family

Antiamoebic Activity of Adenophyllum aurantium (L.) Strother and Its Effect on the Actin Cytoskeleton of Entamoeba histolytica

How Can Ethnobotany Contribute to the History of Western Herbal Medicine? A Mesoamerican Answer

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