Multiple Rheumatoid Nodules of the Renal Cortex

Schned, Alan R.; Moran, Mary; Selikowitz, Stuart M.; Taylor, Thomas H.

doi:10.1001/archinte.1990.00390160131026

Cited by 13 publications

(2 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Carattere sporadico e limitato a pazienti affetti da sindrome di Sjögren hanno le descrizioni di casi di acidosi tubulare distale caratterizzati da paralisi flaccida e ipokaliemia associate ad acidosi ipercloremica e a ridotta risposta ad un carico acido (77)(78)(79). Eccezionale è infine il riscontro di noduli reumatoidi a livello della corticale renale (80).…”

Section: Nefropatia Reumatoide (Tab Iv)unclassified

Kidney involvement in rheumatoid arthritis

Icardi¹,

Araghi²,

Ciabattoni³

et al. 2011

Reumatismo

View full text Add to dashboard Cite

Rheumatoid Arthritis (RA) is a widespread disease and its renal involvement, relatively common, is clinically significant because worsens course and mortality of the primary disease. There is still no agreement on the prevalence of renal disorders in RA: data analysis originates from different sources, as death certificates, autopsies, clinical and laboratory findings and kidney biopsies, each with its limitations. Histoimmunological studies on bioptical specimens of patients with RA and kidney damage, led to clarify prevalent pathologies. In order of frequency: glomerulonephritis and amyloidosis (60-65% and 20-30% respectively), followed by acute or chronic interstitial nephritis. Kidney injury during RA includes secondary renal amyloidosis, nephrotoxic effects of antirheumatic drugs and nephropathies as extra-articular manifestations (rheumatoid nephropathy). Amyloidosis affects survival, increases morbidity and is the main cause of end stage renal disease in patients with RA and nephropathy. Strong association between RA activity and amyloidosis needs the use of immunosuppressive and combined therapies, to prevent this complication and reduce risk of dialysis. Long-lasting and combined RA pharmacotherapy involves various renal side effects. In this review we describe NSAIDs and DMARDs (Disease-Modifying Antirheumatic Drugs) nephrotoxicity, particularly by gold compounds, D-penicillamine, cyclosporine A and methotrexate. Rare cases of IgA glomerulonephritis during immunomodulating therapy with leflunomide and TNF blocking receptor (etanercept) are reported; real clinical significance of this drug-related nephropathy will be established by development of RA treatment. In RA nephropathies, mesangial glomerulonephritis is the most frequent histological lesion (35-60 % out of biopsies from patients with urinary abnormalities and/or kidney impairment), followed by minimal change glomerulopathy (3-14%) and p-ANCA positive necrotizing crescentic glomerulonephritis

show abstract

Section: Nefropatia Reumatoide (Tab Iv)unclassified

Kidney involvement in rheumatoid arthritis

Icardi¹,

Araghi²,

Ciabattoni³

et al. 2011

Reumatismo

View full text Add to dashboard Cite

show abstract

“…Typical locations include the elbow, forearm, digits, tendons, sacrum, and heels. Atypical sites for RNs include pharynx, 41 foot, 42,43 pleura, 44 larynx, 45 choroid plexus, 46 liver, 47 bone, 48 buccal mucosa, 49 and lung, which can be colonized with aspergillus, 50 renal cortex, 51 breast, 52 trachea, 53 intracardiac, 54 penis, 55 and vulva 56 . It has been suggested that the development of cutaneous RNs occurs simultaneous to the development of the nodules in the internal organs 57 …”

Section: Rheumatoid Nodulesmentioning

confidence: 99%

Collagenolytic (necrobiotic) granulomas: part II – the ‘red’ granulomas

Lynch

Barrett

2004

J Cutan Pathol

View full text Add to dashboard Cite

A collagenolytic or necrobiotic non-infectious granuloma is one in which a granulomatous infiltrate develops around a central area of altered collagen and elastic fibers. The altered fibers lose their distinct boundaries and exhibit new staining patterns, becoming either more basophilic or eosinophilic. Within the area of altered collagen, there may be deposition of acellular substances such as mucin (blue) or fibrin (red), or there may be neutrophils with nuclear dust (blue), eosinophils (red), or flame figures (red). These color distinctions can be used as a simple algorithm for the diagnosis of collagenolytic granulomas, i.e. 'blue' granulomas vs. 'red' granulomas. Eight diagnoses are included within these two groupings, which are discussed in this two-part article. In the previously published first part, the clinical presentation, pathogenesis and histologic features of the 'blue' collagenolytic granulomas were discussed. These are the lesions of granuloma annulare, Wegener's granulomatosis, and rheumatoid vasculitis. In this second half of the series, the 'red' collagenolytic granulomas are discussed; these are the lesions of necrobiosis lipoidica, necrobiotic xanthogranuloma, rheumatoid nodules, Churg-Strauss syndrome, and eosinophilic cellulitis (Well's Syndrome).Lynch JM, Barrett TL. Collagenolytic (necrobiotic) granulomas: part II -the 'red' granulomas.

show abstract

Chronische Gelenkentzündungen

Mohr¹

2000

Gelenkpathologie

View full text Add to dashboard Cite

Multiple Rheumatoid Nodules of the Renal Cortex

Cited by 13 publications

References 12 publications

Kidney involvement in rheumatoid arthritis

Kidney involvement in rheumatoid arthritis

Collagenolytic (necrobiotic) granulomas: part II – the ‘red’ granulomas

Chronische Gelenkentzündungen

Contact Info

Product

Resources

About