Multiple primary malignant neoplasm in patients with laryngeal carcinoma

Esposito, Eliana Pia; Bevilacqua, Laura; Guadagno, Maria Tiziana

doi:10.1002/1096-9098(200005)74:1<83::aid-jso18>3.0.co;2-q

Cited by 12 publications

(13 citation statements)

References 15 publications

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“…In the current study, we found that patients with oral cavity squamous cell carcinoma with simultaneous SPT also had poor prognosis when compared with patients without. The possible explanation might be that the presence of simultaneous SPT increased the extent of concurrent resections, which potentially may cause an increased postoperative morbidity and mortality rate . Patients with postoperative morbidity theoretically can lead to delay of treatment plan, which eventually impacts the survival status.…”

Section: Discussionmentioning

confidence: 99%

“…Previous studies reported the rates of second primaries of head and neck squamous cell carcinomas varying from 8% to 21% . A study analyzing patients with laryngeal carcinoma showed a significant reduction of survival rate in patients developing a second primary tumor (SPT) when compared to those without . The 5‐year overall survival rate of patients with head and neck cancer with SPT was significantly poorer than that of patients without .…”

Section: Introductionmentioning

confidence: 99%

“…[4][5][6][7][8] A study analyzing patients with laryngeal carcinoma showed a significant reduction of survival rate in patients developing a second primary tumor (SPT) when compared to those without. 9 The 5-year overall survival rate of patients with head and neck cancer with SPT was significantly poorer than that of patients without. 7 When a second primary cancer developed, the mean survival time was reduced.…”

Section: Introductionmentioning

confidence: 99%

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Survival analysis of patients with oral squamous cell carcinoma with simultaneous second primary tumors

Hsu

Wong

Wang³

et al. 2013

Head & Neck

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Survival analysis of patients with oral squamous cell carcinoma with simultaneous second primary tumors

Hsu

Wong

Wang³

et al. 2013

Head & Neck

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“…Tiroid dışı kanser cerrahisine bağlı boyun diseksiyonu spesimeninde rastlantısal olarak saptanan tiroid karsinomu %0.7-3 arasında belirtilmiş, sıklıkla da papiller karsinom olarak değerlendirilmiştir. [1][2][3] Tiroid dışı nedenlerle boyun diseksiyonu yapı-lan olgularda rastlantısal tiroid papiller karsinom metastazı oluşumu hakkında farklı görüşler mevcuttur. Birinci görüş, tiroid bezinin papiller karsinomuna bağlı metastazı, diğeri ise lateral boyun bölgesinde yer alan embriyonik ektopik tiroid dokusunun malign dejenerasyonu ile ortaya çıktı-ğıdır.…”

Section: Discussionunclassified

“…Ancak, eşza-manlı üst solunum yolu kanseri ve tiroid kanseri nispeten daha sık görülen bir durumdur. [1][2][3] Otopsi çalışmalarında tiroid dokusu içinde %35'lere varan oranda gizli papiller mikro karsinom tespit edilmektedir. Tiroid dışı kanser cerrahisine bağlı boyun diseksiyonu spesimeninde rastlantısal olarak saptanan tiroid karsinomu %0.7-3 arasında belirtilmiştir.…”

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Incidental thyroid carcinoma found during surgery for laryngeal carcinoma: a case report

Çukurova

Mengi²,

Gümüşsoy³

et al. 2011

Kulak Burun Bogaz Ihtis Derg

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Larenks kanseri tanısı ile cerrahi tedavi uygulanan olgularda boyun diseksiyonu spesimeninin histopatolojik incelemesinde larenks kanseri metastazı dışında tiroid metastazına da rastlanmaktadır. Ocak 2008 ve Temmuz 2010 tarihleri arasında kliniğimizde larenks kanseri tanısı konulan ve total veya parsiyel larenjektomi ve boyun diseksiyonu uygulanan 74 olgunun dosyaları geriye dönük olarak incelendi. Parsiyel larenjektomi ve boyun diseksiyonu yapılan iki hastanın boyun diseksiyonu spesimeninde tiroid papiller karsinomu saptandı. Tamamlayıcı tedavi olarak total tiroidektomi uygulandı. Olguların ameliyat sonrası ortalama 9.5 aylık (dağılım 5-14 ay) izlemlerinde herhangi bir nüks veya metastaz ile karşılaşılmadı. Nadir görülmesine rağmen larenks kanserlerinde eşza-manlı tiroid kanseri olasılığı ve gereğinde tamamlayıcı bir cerrahiye gidilebileceği her zaman akılda bulundurulmalıdır.Anahtar Sözcükler: Larenks karsinomu; lenf nodu metastazı; skuamöz hücreli kanser; tiroid kanseri.At the histopathologic examination of neck dissection specimens of the patients who underwent surgical treatment with the diagnosis of laryngeal cancer, tyroid cancer metastases may also be detected in addition to laryngeal cancer metastases. Were retrospectively reviewed the files of 74 patients who were diagnosed with laryngeal cancer and underwent total or partial laryngectomy and neck dissection in our clinic between January 2008 and July 2010. Thyroid papillary carcinoma was found in neck dissection specimen of two patients who underwent partial laryngectomy and neck dissection. Total thyroidectomy was performed to complete the treatment. No recurrence or metastasis was found during the postoperative follow-up for an average of 9.5 months (range 5 to 14 months). Although it is a rare condition, the possibility of coexisting thyroid carcinoma in laryngeal cancer patients and the possible need for completion surgery when required should always be kept in mind.Key Words: Laryngeal carcinoma; lymph node metastases; squamous cell carcinoma; thyroid carcinoma.Larenks kanserleri baş boyun kanserleri içeri-sinde en sık görülen kanser türlerinden olup üst solunum ve sindirim yolları kanserlerinin yaklaşık %30'unu oluştururlar. Eşzamanlı üst solunum yolu ve sindirim yolu kanserleri baş ve boyun kanserleri içinde nadir görülen bir durumdur. Ancak, eşza-manlı üst solunum yolu kanseri ve tiroid kanseri nispeten daha sık görülen bir durumdur. [1][2][3] Otopsi çalışmalarında tiroid dokusu içinde %35'lere varan oranda gizli papiller mikro karsinom tespit edilmektedir. Tiroid dışı kanser cerrahisine bağlı boyun diseksiyonu spesimeninde rastlantısal olarak saptanan tiroid karsinomu %0.7-3 arasında belirtilmiştir. Bunlar genelde papiller tiroid karsinomu Geliş tarihi /

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The risk of second primary tumors in head and neck cancer: A systematic review

et al. 2019

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Background: Second primary tumors (SPTs) are a common cause of reduced life expectancy in patients treated for head and neck cancer (HNC). This phenomenon forms an area to be addressed during posttreatment follow-up.Methods: We conducted a systematic review of literature following PRISMA guidelines, from 1979 to 2019, to investigate incidence of SPTs, synchronous, and metachronous, in HNC population. Results: Our review includes data of 456 130 patients from 61 articles. With a minimum follow-up of 22 months, mean incidence of SPTs was 13.2% (95% CI: 11.56-14.84): 5.3% (95% CI: 4.24-6.36) for synchronous SPTs and 9.4% (95% CI: 7.9-10.9) for metachronous SPTs. The most frequent site for SPTs was head and neck area, followed by the lungs and esophagus.Conclusion: Although with wide variations between studies, the rate of SPTs in HNC patients is high. Given the impact in the prognosis, we must develop strategies for the early diagnosis of SPTs. K E Y W O R D Shead and neck cancer, metachronous, second primary tumor, squamous cell carcinoma, synchronous

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Multiple primary malignant neoplasm in patients with laryngeal carcinoma

Abstract: The incidence of new tumors in patients with laryngeal carcinoma is not linked to the site, size, staging, or grade of differentiation of the index tumor.

Cited by 12 publications

References 15 publications

Survival analysis of patients with oral squamous cell carcinoma with simultaneous second primary tumors

Survival analysis of patients with oral squamous cell carcinoma with simultaneous second primary tumors

Incidental thyroid carcinoma found during surgery for laryngeal carcinoma: a case report

The risk of second primary tumors in head and neck cancer: A systematic review

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