Multiple papules on the face. Multiple miliary osteoma cutis

Levell, N. J.

doi:10.1001/archderm.130.3.370

Cited by 10 publications

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“…After an extensive literature search using both PubMed and Web of Science citation analysis and especially also looking for articles published in languages other than English we found only 47 cases which satisfy the criteria for MMOC (Table 3). 4–6,11–47 These cases included 41 female and six male patients of African, Caucasian, East Asian and Native American origin. The osteomas started to occur at a mean age of 47 years (range 17–79) and usually appeared on the face.…”

Section: Discussionmentioning

confidence: 99%

Multiple miliary osteoma cutis is a distinct disease entity: four case reports and review of the literature

Myllylä

Haapasaari²,

Palatsi

et al. 2011

British Journal of Dermatology

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Section: Discussionmentioning

confidence: 99%

Multiple miliary osteoma cutis is a distinct disease entity: four case reports and review of the literature

Myllylä

Haapasaari²,

Palatsi

et al. 2011

British Journal of Dermatology

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“…22 Levell reported that a long standing inflammation may cause mesenchymal cells differentiation into osteoblasts. 9 In fact, in our case, the gravidarum acne may have resulted in a fibrous scar and an osteoblastic metaplasia. According to our case, Thielen and coworkers reported an association of miliary osteoma cutis and chronic inflammatory acne.…”

mentioning

confidence: 55%

Miliary osteoma cutis of the face

2008

Journal of the American Academy of Dermatology

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Background: Miliary osteoma cutis (OC) of the face is a rare benign extra skeletal bone formation. For our knowledge, only 23 cases have been reported in the English literature. These lesions may be primary or secondary. They cause diagnostic, therapeutic and cosmetic concern especially in women who are usually concerned. Our purpose is to present a case which is completely documented with the clinical, histological and radiological findings. We also report a possible pathogenic theory according to our histologic findings. Main observation:We report a case of a multiple miliary OC of the face in a 45-year-old woman which suffered from gravidarum acne. These lesions were treated by focal surgical treatment.Conclusions: Based on our histological findings, an osteoblastic metaplasia seems to be a possible pathogenic theory. This metaplasia seems to be secondary to a chronic inflammation. Concerning therapeutic procedures, they are non consensual and debated and are based on surgical or medical treatment. More reports are needed in order to assess the therapeutic management of this disease and its inducing factors. (J Dermatol Case Rep.

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“…The pathogenesis of the disease remains debated, the more plausible being osteoblastic metaplasia of mesenchymal cells such as fibroblasts. [ 3 ] Level and Lawrence[ 4 ] reported that a long-standing inflammation can cause mesenchymal cells to differentiate into osteoblasts.…”

Section: Discussionmentioning

confidence: 99%

Multiple miliary osteoma cutis of face

Lahiry

2018

J Cutan Aesthet Surg

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Multiple miliary osteoma cutis is an uncommon condition presenting as multiple skin-colored papules of variable sizes on the face. A 48-year-old woman presented with multiple skin-colored hard papules on both cheeks. Examination revealed firm-to-hard dome-shaped asymptomatic papules in cluster over both cheeks. A punch biopsy was performed, which showed evidence of focal bony trabeculae with associated normal appendages. Few larger papules were incised and followed up with curettage of bony material and closed. All lesions could not be incised and removed because of large number of lesions in cluster.

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Multiple papules on the face. Multiple miliary osteoma cutis

Cited by 10 publications

References 0 publications

Multiple miliary osteoma cutis is a distinct disease entity: four case reports and review of the literature

Multiple miliary osteoma cutis is a distinct disease entity: four case reports and review of the literature

Miliary osteoma cutis of the face

Multiple miliary osteoma cutis of face

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