Case Presentation An 84-year-old woman presented to an outside institution with a 1-month history of generalized malaise, anorexia, abdominal distension, shortness of breath, and unintentional 20-pound weight loss. She had a past medical history of JAK2-positive polycythemia rubra vera, stage 4 chronic kidney disease, type 2 diabetes mellitus, and hypothyroidism. Her surgical history included a total vaginal hysterectomy and bilateral salpingo-oophorectomy in 1984. Since moving to the United States in 1972, she undertook routine visits to her native country, India. The patient's diabetes was managed with metformin/glipizide and her primary care provider had changed this regimen to sitagliptin 2 weeks prior due to worsening chronic kidney disease. On presentation, vital signs were within normal range aside from mild tachycardia. Her exam was notable for atrophy of the extremities and a protuberant abdomen with a positive fluid wave and shifting dullness. On pelvic examination, the uterus was surgically absent and there was no cul-de-sac nodularity on bimanual or rectovaginal exam. Relevant laboratory values included: hemoglobin 11.7 g/dL, white blood cell count 9850/mm 3 , platelet count 468 000 mm 3 , blood urea nitrogen 46 mg/dL, creatinine 2.5 mg/dL, albumin 2.4 g/dL, albumin-corrected calcium 12.