Multiple myeloma with lung plasmacytoma

Prasad, Rajendra; Verma, Sanjeev; Sodhi, Rakhi

doi:10.4103/0970-2113.80331

Cited by 8 publications

(10 citation statements)

References 5 publications

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“…Whereas the most common thoracic disorders associated with myeloma are bone involvement or pulmonary infiltrates secondary to a complicating infectious process, primary thoracic involvement by myeloma occurs in less than 1% of cases [1,2].…”

Section: Introductionmentioning

confidence: 99%

Multiple myeloma presenting as thoracic plasmacytoma – Two rare cases

Saha¹,

Bhattacharya²,

Deb³

et al. 2014

Egyptian Journal of Chest Diseases and Tuberculosis

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Section: Introductionmentioning

confidence: 99%

Multiple myeloma presenting as thoracic plasmacytoma – Two rare cases

Saha¹,

Bhattacharya²,

Deb³

et al. 2014

Egyptian Journal of Chest Diseases and Tuberculosis

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“…The diagnosis of extramedullary plasmacytoma was confirmed by histopathology and similar cases were reported in the literature. [ 15 16 ]…”

Section: Discussionmentioning

confidence: 99%

Image-guided fine needle aspiration cytology of intrathoracic lesions

Abraham

Suresh

Sridevi

et al. 2019

J Cytol

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Background:Percutaneous, image-guided transthoracic fine needle aspiration cytology (TTFNAC) is a rapid, yet accurate, and well-established diagnostic method used in the cytological evaluation of intrathoracic lesions. The study was done to determine the utility of image-guided TTFNAC in diagnosis of intrathoracic lesions.Subjects and Methods:A retrospective analysis of all cases who underwent image-guided TTFNAC of a suspected intrathoracic lesion, in a tertiary care hospital was done over a period of 3 years.Results:During the study period, 124 cases of image-guided FNAC of intrathoracic lesions were obtained. The mean age at presentation was 60.5 years with M:F: 3.6:1. Neoplastic lesions (71.5%) outnumbered the nonneoplastic lesions (28.5%). The most common tumor was adenocarcinoma (25%) followed by squamous cell carcinoma (SCC, 11%), and small cell carcinoma (5%). There was one case each of anaplastic carcinoma, plasmacytoma, bronchoalveolar carcinoma, and non-Hodgkin lymphoma (NHL). Most of the lesions were found on the right side and upper lobe. Among the mediastinal lesions, we found two cases of thymoma and one case each of NHL)/primitive neuroectodermal tumor (PNET), NHL, and small cell carcinoma metastasis to lymph node followed by ten cases of inflammatory lesions and seven cases of tuberculosis (TB).Conclusion:Image-guided TTFNAC of intrathoracic lesions is a safe method when done by well-trained medical personnel with lesser rate of complications. An early accurate diagnosis of malignancy can be made based on the cytological features; however, further subtyping of the malignancy may sometimes be difficult due to overlapping cytological features. TTFNAC can be a diagnostic tool for identifying nonneoplastic lesion such as TB. Hence, image-guided FNAC aids in early diagnosis and management of patients with intrathoracic lesions.

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“…The differential diagnosis of MM includes other plasma cell proliferative disorders mentioned above such as MGUS, SMM, solitary plasmacytoma or primary amyloidosis, and other diagnoses such as lymphoma, chronic lymphocytic leukaemia, bone malignancy and metastatic carcinoma 8…”

Section: Discussionmentioning

confidence: 99%

“…A comparative analysis of pulmonary presentations in MM by various authors revealed the following: mass lesion (hilar or intraparenchymal), pulmonary calcification, multiple lung nodules, pneumonia, pleural involvement and rib erosion 8. A review of 958 patients with MM, published in 1978, revealed that thoracic skeletal or pleuropulmonary involvement or both were present in 46% (443) of patients.…”

Section: Discussionmentioning

confidence: 99%

An unusual presentation of multiple myeloma

et al. 2018

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The authors report a case of a 58-year-old woman, ex-smoker, who was referred to the respiratory clinic with a presumed unresolving airspace shadowing in the right lung. Further evaluation of the shadowing with a CT thorax revealed rib lesions, a pancreatic lesion and multiple liver lesions, making the diagnosis of metastatic pancreatic carcinoma most likely. However, further blood investigations and imaging eventually revealed the cause for the shadowing to be multiple myeloma, since the unresolving shadowing was actually a rib lesion.

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Multiple myeloma with lung plasmacytoma

Cited by 8 publications

References 5 publications

Multiple myeloma presenting as thoracic plasmacytoma – Two rare cases

Multiple myeloma presenting as thoracic plasmacytoma – Two rare cases

Image-guided fine needle aspiration cytology of intrathoracic lesions

An unusual presentation of multiple myeloma

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