Multiple microlithiasis in bilateral parotid glands as the initial clinical manifestation of primary Sjögren’s syndrome

Dobai, Adrienn; Pataky, Levente; Barabás, József

doi:10.1007/s11282-017-0294-8

Cited by 2 publications

(2 citation statements)

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“…The presence of bilateral or multiple findings in both parotid cysts and parotid calcifications was found to be highly suggestive of SS, which is consistent with previous studies [16][17][18][19][20][22][23][24][25]. Additionally, parotid calcifications in the PG parenchyma or those without coexisting calcifications in other tissues were significantly associated with SS.…”

Section: Discussionsupporting

confidence: 89%

“…Several other imaging findings have been reported to be associated with SS. Parotid cysts and parotid calcifications in SS have been documented for more than 20 years [15][16][17][18][19][20][21][22][23][24][25]. Histopathologically, parotid cysts in SS are benign lymphoepithelial lesions resulting from cyst formation by epimyoepithelial islands in lymphoepithelial sialadenitis [26].…”

Section: Introductionmentioning

confidence: 99%

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Three Signs to Help Detect Sjögren’s Syndrome: Incidental Findings on Magnetic Resonance Imaging and Computed Tomography

Takagi,

Katayama,

Eida

et al. 2023

JCM

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This study aimed to retrospectively investigate the prevalence of Sjögren’s syndrome (SS) among patients with ranulas, parotid cysts, or parotid calcifications; identify the characteristic magnetic resonance imaging (MRI) or computed tomography (CT) findings of the lesions associated with SS; and compare the SS disease stages among SS patients with the three lesion types. A total of 228 patients with the lesions were classified into SS, possible SS, and non-SS groups. The prevalence of SS among patients with ranulas, parotid cysts, or parotid calcifications was 16%, 24%, and 40%, and the rates of either SS or possible SS were 25%, 41%, and 64%, respectively. SS was associated with (i) ranulas: ≤17 mm; (ii) parotid cysts: bilateral and multiple; and (iii) parotid calcifications: in females, bilateral, multiple, parenchymal, and no coexisting calcifications in other tissues. SS patients with ranulas were significantly younger and had lower submandibular gland stage scores on MRI/CT than those with other lesions. Additionally, in 58% and 15% of SS patients with ranulas and parotid calcifications, respectively, detection of the lesions led to the diagnosis of primary SS. Therefore, recognizing the prevalence of SS among patients with these lesions and the findings associated with SS can help detect undiagnosed SS.

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