Multiple intracranial lipoma: A case report

Abstract

We report on a male epileptic patient, presently 27 years old, who has suffered complex-partial attacks for 19 years. Under treatment with carbamazepine the seizures were completely controlled. In addition, the patient exhibited partial hypopituitarism. CT and MRI revealed the presence of 2 lipomas, one located within the optico-chiasmatic cistern and the other one in the medial temporal lobe. To our knowledge, this combination of the generally rare lesions has not been described yet.

Hypothalamic lipoma adjacent to mamillary bodies

“…They consist of mature fat cells and connective tissue containing blood vessels. These benign tumors are developmental lesions, which probably result from the persistence and abnormal differentiation of the primitive meninges [7,15]. Twenty-two cases of intracranial lipoma in the suprasellar region have been reported [14].…”

“…Lipomas localized in the ambient and quadrigeminal cisterns often present with signs of intracranial pressure caused by hydrocephalus [13]. Other neurological symptoms or endocrinological disturbances are very rare [7].…”

Intracranial Lipoma

“…Localization at the quadrigeminal cistern or in the cisterna ambiens can impair the circulation of liquor and cause signs of increased intracranial pressure [1]. Endocrinological abnormalities are very rare but possible [13]. Sylvian fissure located lipomas can cause an epilepsia [4].…”

Lipoma intracraniano – Revisão da literatura

“…10 Lipomas localizados na fissura silviana podem causar epilepsia. 3,6,10,28,30,54,64 Hädecke et al 65 relataram um paciente de 29 anos que tinha crises parciais complexas por 19 anos, cujo exame de imagem revelou a presença de múltiplos lipomas intracranianos. Zimmermann et al 66 descreveram um caso de lipoma localizado no ângulo pontocerebelar em uma paciente de 27 anos, com história prévia de dois meses de vertigem e perda auditiva progressiva.…”

“…17 Diagnóstico diferencial é feito com cistos dermoides e teratomas, que podem apresentar padrões de TC similares, com acentuada hipoatenuação. 3,6,10,50,65 Na RM o cisto dermoide apresenta-se hiperintenso em T1 e com padrão de sinal heterogêneo em T2 com efeito A B…”