Multiple Hemolymphangioma of the Visceral Organs

Zhang, Deng‐Yong; Ma, Xiang; Wang, Qiuyue; Sun, Wang-Liang; Wu, Wei; Cui, Peng

doi:10.1097/md.0000000000001126

Cited by 12 publications

(7 citation statements)

References 17 publications

(18 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nevertheless, multi-focal hemolymphangioma is rare. Only one previous study has reported on a female patient with hemolymphangioma in the spleen and retroperitoneum ( 3 ). Of the 4 cases in the present case report, there was 1 patient who had multifocal hemolymphangioma in the mediastinum and spleen.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Radiographic findings of hemolymphangioma in four patients: A case report

et al. 2017

View full text Add to dashboard Cite

Due to the rarity of hemolymphangioma, a limited number of cases of the disease have been reported in the literature thus far. The present case report describes the cases of 4 patients with hemolymphangioma that were diagnosed and treated at the Second Affiliated Hospital of Xi'an Jiaotong University (Xi'an, China). All patients were female, with a mean age of 44.7 years and a mean duration of symptoms prior to diagnosis of 2.7 years. The diagnosis of hemolymphangioma was determined by postoperative histopathology in all patients. A total of 2 patients were diagnosed with tumors that exhibited cystic characteristics (one in the mediastinum and the other in the neck), which was determined by computed tomography and magnetic resonance imaging. Another of the patients' tumors was located in the left forearm, and 1 patient had multifocal hemolymphangioma in the mediastinum and spleen. All patients underwent surgery and were asymptomatic during the follow-up periods (range, 8–15 months). In the present case report, the radiographic findings of the 4 cases are presented, including the unusual imaging characteristics that were observed, and relevant reports in the literature are discussed.

show abstract

Section: Discussionmentioning

confidence: 99%

“…The majority of cases in the literature had successful postoperative courses of treatment. Postoperative follow-up is necessary due to the potential recurrence or metastasis of the tumor ( 3 ). All cases in the present case reports remained asymptomatic during postoperative follow-up period.…”

Section: Discussionmentioning

confidence: 99%

Radiographic findings of hemolymphangioma in four patients: A case report

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Most researchers believe that hemolymphangioma is commonly a benign disease and has no invasive ability [ 1 , 2 , 5 – 11 , 13 – 23 ]. But some studies recently found that it can invade the adjacent structures [ 3 , 4 , 12 ]. Toyoki et al discovered that the tumor from pancreas invaded to the duodenum to cause the duodenal bleeding [ 3 ].…”

Section: Discussionmentioning

confidence: 99%

“…In 2009, Sun and colleagues reported that the giant tumor originated in pancreas, infiltrated the transverse mesocolon and greater omentum, and tightly adhered to duodenum and superior mesenteric artery [ 4 ]. Recently, Zhang et al found multiple hemolymphangioma of the visceral organs and reported the retroperitoneal tumor extending to the left colon and small bowel mesentery [ 12 ].…”

Section: Discussionmentioning

confidence: 99%

Occipitocervical Hemolymphangioma in an Adult with Neck Pain and Stiffness: Case Report and Literature Review

Zhang

Pang

et al. 2017

Case Reports in Medicine

View full text Add to dashboard Cite

Introduction Hemolymphangioma is an extremely rare malformation of the lymphatic and blood vessels. A limited number of hemolymphangioma cases occurring in the pancreas, extremities, spleen, and other organs have been reported until September 2017. To the best of our knowledge, no cases of hemolymphangioma in the occipitocervical region have been reported in the literature. Case Presentation We reported the case of a 23-year-old male patient with an occipitocervical lesion presenting atypically as neck pain and stiffness over a period of five months. Although hemolymphangioma has historically demonstrated a female predilection (2.25 : 1 female to male) and presentation in the third to fourth decades of life, this case is an atypical manifestation occurring in a young male patient. The clinical characteristics and management choices of this uncommon case of hemolymphangioma in the occipitocervical region are discussed, and a review based on the available literature is also presented. Conclusion Hemolymphangioma of the occipitocervical region is an uncommon presentation of a rare lesion. Although rare, hemolymphangioma should be considered a differential diagnosis for masses occurring in the occipitocervical region. Complete surgical resection is the treatment of choice and affords a good prognosis.

show abstract

“…Hemolymphangioma is a congenital and benign malformation of both lymphatic and blood vessel. [1] It is preferentially situated in the head and neck, seldom in the spleen, small intestine, orbit, pancreas, vermiform appendix, or omentum. [2,3] Hemolymphangioma rarely involves bones and bladder simultaneously.…”

Section: Introductionmentioning

confidence: 99%

Hemolymphangioma involving bones and bladder detected on 68Ga-NEB PET/CT

et al. 2019

View full text Add to dashboard Cite

Rationale: Hemolymphangioma is a rare developmental defect of combined vasal and lymphatic vasculature. It is very rare that hemolymphangioma affects the bones and bladder simultaneously, and this condition has never been reported in PubMed. Patient concerns: A 12-year-old male has a history of hospitalization for recurrent episodes of chyluria of 8 years duration and progressively worsening gross hematuria with right hip pain for 6 months. Diagnosis: Chylous test of urine fluid was positive. There was no organic disease in the kidneys. 68 Ga-NOTA-Evans Blue (NEB) positron emission tomography/computed tomography (PET/CT) images demonstrated clearly several round and strip-shaped low-density shadows with mildly increased radioactive uptake in both bladder wall and pelvis, including sacral, pubic, and ischial bones. Histopathological analysis of biopsy on pubic and ischial bones confirmed the diagnosis of hemolymphangioma. Interventions: The patient received treatment with traditional Chinese medicine. Outcomes: At the 6-month follow-up visit, the patient's symptoms of chyluria, hematuria, and pain were all mitigated. Lessons: Hemolymphangioma is a rare benign disease. 68 Ga-NEB PET/CT is a specific method for the lymphatic system, and it might provide more accurate and comprehensive information about the disorder of the lymphatic system compared with CT and magnetic resonance imaging. When patients suffer from suspected lesions of the lymphatic system, 68 Ga-NEB PET/CT might be recommended.

show abstract

Multiple Hemolymphangioma of the Visceral Organs

Cited by 12 publications

References 17 publications

Radiographic findings of hemolymphangioma in four patients: A case report

Radiographic findings of hemolymphangioma in four patients: A case report

Occipitocervical Hemolymphangioma in an Adult with Neck Pain and Stiffness: Case Report and Literature Review

Hemolymphangioma involving bones and bladder detected on 68Ga-NEB PET/CT

Contact Info

Product

Resources

About