“…In the past three decades, all explorations of tfd gene clusters, from a comparative genomic point of view, have been focused primarily on their tandem matching with the canonical gene structure of tfdI и tfdII gene clusters. A lot of both canonical and non-canonical clusters have been identified, amongst them: tfdT-CDEF (Liu et al, 2001), tfdDRCEBKAF (Poh et al, 2002), tfdCDEF and tfdCIIEIIBKA (Delftia acidovorans P4a), tfdRCEBKA (Vedler et al, 2004), tfdC2E2F2 and tfdDRFCE (Thiel et al, 2005), tfdAKBECR (Sen et al 2011), tfdRDCEFBKA (Kim et al, 2013), tfdBCDEFKR (Nielsen et al, 2013), tfdFAKBIEICIDIRI and tfdCIIEIIBII (Sakai et al, 2014), tfdFEDCT (Ricker et al, 2016), tfdBIFIEIDICIT and variations of the tfdKBIIFEIICIIDIIR cluster with deletions (Nguyen et al, 2019), tfdBFET, tfdAKBFECDR and tfdBFEDC (Xiang et al, 2020), tfdBFEDCS, tfdFE(tctC)DCS (Nguyen et al, 2021a), tfdBaFRDEC (Hayashi et al, 2021), tfdCDEF (Yamamoto-Tamura et al, 2021), tfdEICIFIRDI,K,BI, tfdDII,FIIEIICII,BII (Zhang et al, 2023) and other cluster structures.…”