Multiple Gastrointestinal Hemangiomatosis Successfully Treated With Propranolol

Akçam, Mustafa; Pirgon, Özgür; Salman, Hakan; Kockar, Cem

doi:10.1097/mpg.0b013e31829530af

Cited by 4 publications

(9 citation statements)

References 3 publications

(4 reference statements)

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“…In a previous study, three patients were successfully treated with pharmacotherapy with additional argon plasma coagulation and electrocoagulation [ 2 4 8 ]. Similar to this case, a patient with multiple hemangiomas in the stomach and intestines successfully treated with propranolol was reported [ 3 ]. The most serious known adverse e ffects of propranolol are bradycardia, hypoglycemia and bronchospasm [ 19 ].…”

Section: Discussionsupporting

confidence: 64%

“…Gastric hemangiomas, that occur more rarely, are frequently observed as isolated lesions. So far, 22 cases of gastric hemangioma have been reported in pediatric patients; of these, 13 were isolated cases [ 1 2 3 4 ]. Four cases of hemangiomas were reported in the neonatal period, three of which were reported as isolated gastric hemangioma [ 2 4 5 10 ].…”

Section: Discussionmentioning

confidence: 99%

“…There was no GIS bleeding and in control endoscopic examination performed three weeks later, the lesion had regressed and medical treatment continued. In a previous study of 22 gastric hemangioma cases reported in childhood, surgical intervention was performed in all cases except four [ 1 2 3 4 ]. Presently, oral propranolol may be considered as first-line treatment in infantile hemangiomas [ 18 ].…”

Section: Discussionmentioning

confidence: 99%

“…GIS hemangiomas in the stomach are rare. So far, 22 cases of gastric hemangioma have been reported in pediatric patients; of these, 13 were isolated cases [ 1 2 3 4 ]. Esophagogastroduodenoscopy, angiography and computed tomography are valuable in diagnosis of gastric hemangiomas.…”

Section: Introductionmentioning

confidence: 99%

“…Propranolol is commonly used with corticosteroids to treat non-gastric GIS hemangiomas [ 7 ]. However, pharmacotherapy has often been performed in a small number of hemangioma patients with multiple lesions in the GIS, wherein surgical possibilities are limited [ 2 3 4 8 ]. We report the case of a neonate with an isolated gastric hemangioma, presented with massive gastrointestinal bleeding, and the hemangioma shrunk with propranolol therapy after bleeding was controlled with antisecretory drugs.…”

Section: Introductionmentioning

confidence: 99%

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A Newborn with Gastric Hemangioma Treated Using Propranolol

Kaya

Gökçe

Güngör

et al. 2018

Pediatr Gastroenterol Hepatol Nutr

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Gastric hemangiomas are rare benign vascular tumors that can cause severe gastrointestinal system bleeding. We presented the case of a neonate with fresh bleeding and melena from the orogastric tube and detected gastric hemangioma in esophagogastroduodenoscopic examination. Propranolol is widely used in treatment of cutaneous hemangiomas and non-gastric gastrointestinal system hemangiomas. However, the surgical approach is preferred for treating gastric hemangiomas, and there are few reports of gastric hemangiomas associated with non-surgical treatment. Gastric hemorrhage decreased with antacid and somatostatin treatment. Propranolol treatment was initiated before the surgery decision. After three weeks of treatment, we observed regression in the hemangioma with endoscopic evaluation. During the course of treatment, the patient's gastrointestinal system bleeding did not recur, and there were no side effects associated with propranolol.

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Section: Discussionsupporting

confidence: 64%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

A Newborn with Gastric Hemangioma Treated Using Propranolol

Kaya

Gökçe

Güngör

et al. 2018

Pediatr Gastroenterol Hepatol Nutr

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Peritoneal cavernous hemangiomatosis: A case report

Chen

Diao

et al. 2019

WJCC

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BACKGROUND Cavernous hemangiomatosis in the liver and spleen has been reported, but it occurs less commonly in the peritoneum. Here we report a case of peritoneal cavernous hemangiomatosis and share some valuable information about this disease. CASE SUMMARY A 57-year-old Chinese man had a huge abdominal mass with abdominal distention and a significant reduction of food consumption. An enhanced abdominal and pelvic computed tomography and positron emission tomography–computed tomography revealed multiple cystic masses on the peritoneum, greater omentum, small intestinal mesentery and the surface of the spleen, and a high maximum standardized uptake value of the largest cystic lesion. Exploratory laparotomy was performed, and multiple cystic masses were found on the surface of the peritoneum, greater omentum, mesentery of the small intestine, and surface of the liver and spleen. Dark red bloody cystic fluid was present in the cystic tumor. Pathological examination showed that in the stromal components, the irregular vascular wall was thin. The vessel lumen was interlinked, and the lumen was lined with flat endothelium. According to the intraoperative findings and pathologic results, the patient was diagnosed with peritoneal cavernous hemangiomatosis. CONCLUSION The possibility of peritoneal cavernous hemangiomatosis should be considered when multiple cystic masses are found in the abdominal cavity by preoperative examination.

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Mechanical intestinal obstruction due to isolated diffuse venous malformations in the gastrointestinal tract: A case report and review of literature

Lü

et al. 2020

WJCC

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Multiple Gastrointestinal Hemangiomatosis Successfully Treated With Propranolol

Cited by 4 publications

References 3 publications

A Newborn with Gastric Hemangioma Treated Using Propranolol

A Newborn with Gastric Hemangioma Treated Using Propranolol

Peritoneal cavernous hemangiomatosis: A case report

Mechanical intestinal obstruction due to isolated diffuse venous malformations in the gastrointestinal tract: A case report and review of literature

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