A Newborn with Gastric Hemangioma Treated Using Propranolol

Abstract

Gastric hemangiomas are rare benign vascular tumors that can cause severe gastrointestinal system bleeding. We presented the case of a neonate with fresh bleeding and melena from the orogastric tube and detected gastric hemangioma in esophagogastroduodenoscopic examination. Propranolol is widely used in treatment of cutaneous hemangiomas and non-gastric gastrointestinal system hemangiomas. However, the surgical approach is preferred for treating gastric hemangiomas, and there are few reports of gastric hemangiomas associated with non-surgical treatment. Gastric hemorrhage decreased with antacid and somatostatin treatment. Propranolol treatment was initiated before the surgery decision. After three weeks of treatment, we observed regression in the hemangioma with endoscopic evaluation. During the course of treatment, the patient's gastrointestinal system bleeding did not recur, and there were no side effects associated with propranolol.

Transumbilical single-site laparoscopic treatment of small intestinal cavernous hemangioma in child: a case report

“…However, these treatments carry risks of uncontrolled gastrointestinal bleeding, intestinal perforation, and a high recurrence rate (22). Drug therapy, such as oral propranolol, has been reported as a successful treatment for neonatal gastric hemangioma (23). However, surgical resection is still the preferred treatment for symptomatic hemangiomas that present with life-threatening bleeding, intussusception, intestinal obstruction, and intestinal perforation.…”

Cavernous Gastric Hemangioma as an Unusual Cause of Upper Gastrointestinal Bleeding in a Young Woman

“…However, therapeutic endoscopic intervention is not impossible for smaller lesions as 1 author has described a 14-mm cavernous GH being treated successfully via endoscopic resection [14]. Other nonsurgical treatments of GH including propranolol [15] and argon plasma coagulation [9] have also been described but only in infantile patients.…”

A rare case of gastrointestinal bleeding caused by gastric capillary hemangioma

“…For submucosal lesions of <2 cm in diameter, ESD may be performed after appropriate preoperative evaluation [ 8 ]. Other non-surgical treatments for gastric hemangiomas, including propranolol [ 9 ] and argon plasma coagulation [ 10 ], sclerotherapy, and others, have only been reported in pediatric patients.…”