Multiple-day high-dose beetroot juice supplementation does not improve pulmonary or muscle deoxygenation kinetics of well-trained cyclists in normoxia and hypoxia

Rokkedal-Lausch, Torben; Franch, Jesper; Poulsen, Mathias Krogh; Thomsen, Lars Pilegaard; Weitzberg, Eddie; Kamavuako, Ernest Nlandu; Karbing, Dan Stieper; Larsen, Ryan Godsk

doi:10.1016/j.niox.2021.03.006

Cited by 4 publications

(6 citation statements)

References 63 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, muscle oxygenation has been shown to improve during cycling exercise from transitions of low-to high-intensity work rates [17] and during faster cadences relative to slow cadences in cycling [20]. In contrast, NO 3 − has also been shown to be ineffective at influencing muscle oxygenation [66,[77][78][79]. In hypoxic states, NO 3 − supplementation has been shown to preserve muscle oxygenation [80,81] but also shown to have no effect [82].…”

Section: Influence Of No 3 − Supplementation On Muscle Oxygenationmentioning

confidence: 99%

Effects of Dietary Nitrate Supplementation on Performance and Muscle Oxygenation during Resistance Exercise in Men

et al. 2022

View full text Add to dashboard Cite

The purpose of the current study was to assess the effects of acute and short-term nitrate (NO3−)-rich beetroot juice (BR) supplementation on performance outcomes and muscle oxygenation during bench press and back squat exercise. Fourteen recreationally active males were assigned in a randomized, double-blind, crossover design to supplement for 4 days in two conditions: (1) NO3−-depleted beetroot juice (PL; 0.10 mmol NO3− per day) and (2) BR (11.8 mmol NO3− per day). On days 1 and 4 of the supplementation periods, participants completed 2 sets of 2 × 70%1RM interspersed by 2 min of recovery, followed by one set of repetitions-to-failure (RTF) at 60%1RM for the determination of muscular power, velocity, and endurance. Quadriceps and pectoralis major tissue saturation index (TSI) were measured throughout exercise. Plasma [NO3−] and nitrite ([NO2−]) were higher after 1 and 4 days of supplementation with BR compared to PL (p < 0.05). Quadriceps and pectoralis major TSI were not different between conditions (p > 0.05). The number of RTF in bench press was 5% greater after acute BR ingestion compared to PL (PL: 23 ± 4 vs. BR: 24 ± 5, p < 0.05). There were no differences between BR and PL for RTF for back squat or power and velocity for back squat or bench press (p > 0.05). These data improve understanding on the ergogenic potential of BR supplementation during resistance exercise.

show abstract

Section: Influence Of No 3 − Supplementation On Muscle Oxygenationmentioning

confidence: 99%

Effects of Dietary Nitrate Supplementation on Performance and Muscle Oxygenation during Resistance Exercise in Men

et al. 2022

View full text Add to dashboard Cite

show abstract

“… 26 Not all studies have shown an ergogenic effect when trained athletes performed 10–15 km cycling, 10 km running and 10 km roller-skiing time-trials in hypoxia after beetroot supplementation. 31 , 33 , 48 , 61 , 62 However, this finding is not consistent and at least two studies have found a positive effect on 1.5 km running and 16.1 km cycling performance. 23 , 25 Jones and colleagues further explained that the discrepancy could be caused by methodological limitations, relatively smaller sample size and lack of sport-specific tests in studies of elite or well-trained athletes.…”

Section: Discussionmentioning

confidence: 90%

The effects of nitrate ingestion on high-intensity endurance time-trial performance: A systematic review and meta-analysis

Wong

Sim

Burns

2022

Journal of Exercise Science & Fitness

View full text Add to dashboard Cite

“…as a means of enhancing muscle performance or recovery). The following situations were compared with some control scenarios to evaluate the muscle oxygenation responses and the potential benefits of the tested product or intervention: the use of a tracksuit jacket with heating elements [ 162 ], nonivamide-nicoboxil cream [ 180 ], sports compression garment ( n = 3 for lower limb: tights, calf sleeve, socks; n = 1 for upper limb, forearm) [ 18 , 19 , 31 , 107 ], core and skin cooling [ 136 ], undergoing thigh cooling by a water-circulating pad [ 85 ] and oral supplementation with dietary inorganic nitrate-rich and placebo beetroot juice [ 32 , 33 , 40 , 43 , 63 , 75 , 76 , 131 , 146 , 158 , 183 , 190 , 201 ], supplementation with pomegranate extract and co-supplementation with N -acetylcysteine [ 39 ], protein powder [ 134 ], pre-exercise ingestion of a drink with higher dissolved O 2 [ 135 ], anthocyanin-rich New Zealand blackcurrant supplementation [ 27 ], 1 h after a single dose of mango leaf extract rich in mangiferin and lecithin, or mango leaf extract rich in mangiferin and quercetin, phospholipids addition [ 53 – 55 ], red spinach extract [ 121 ], citrulline drink/citrulline malate [ 190 , 196 ], l -arginine [ 141 , 143 ], Montmorency cherry polyphenols [ 67 ], eicosapentaenoic acid and docosahexaenoic acid (fish oil) [ 198 ], caffeine intake [ 189 ] and dark chocolate [ 81 ].…”

Section: Resultsmentioning

confidence: 99%

“…The extent of notable changes in the muscle oxygenation levels measured with NIRS indicators in response to various physiological stressors (hypoxia, exercise intensity, exercise profile, training) was investigated in the following cases: repeated sprint training [ 14 , 15 , 34 , 107 , 157 , 165 , 168 , 172 , 188 , 191 , 192 ], high-intensity interval training [ 15 , 25 , 43 , 137 , 157 , 164 , 184 ], voluntary hypoventilation at low lung volume versus normal breathing [ 17 , 34 , 88 , 89 , 151 ], inspiratory muscle training/pre-activation [ 45 , 97 , 100 , 112 , 113 , 140 , 152 , 181 , 187 ], blood flow restriction [ 12 , 14 , 147 , 149 , 191 , 192 ], intermittent bilateral cuff inflation of lower limbs with three 5/10-min ischemia–reperfusion cycles [ 53 ], hypoxia (normo- and hypo-baric) [ 14 , 35 , 59 , 72 , 76 , 77 , 90 , 108 , 123 , 129 , 130 , 137 , 142 , 148 – 150 , 168 , 188 , 191 , 192 , 200 ], ischem...…”

Section: Resultsmentioning

confidence: 99%

“…Cherry polyphenols [67] and mango leaf extract rich in mangiferin [53][54][55] may be useful nutritional aids for improving muscular endurance performance. Contrarily, this does not appear to be the case for acute dietary nitrate supplementation [33,63,75,76,158,183,190], citrulline [190,196], l-arginine, red spinach extract [121], dark chocolate [181] and caffeine [189]. Additionally, mechanical ergogenic aids like compression clothing [18,19,31,107] tend to increase blood flow and muscle oxygenation, especially at rest.…”

Section: Meaningful and Promising Applications Of Muscle Oxygenation ...mentioning

confidence: 99%

See 1 more Smart Citation

Muscle Oximetry in Sports Science: An Updated Systematic Review

Perrey,

Quaresima,

Ferrari

2024

Sports Med

View full text Add to dashboard Cite

Background In the last 5 years since our last systematic review, a significant number of articles have been published on the technical aspects of muscle near-infrared spectroscopy (NIRS), the interpretation of the signals and the benefits of using the NIRS technique to measure the physiological status of muscles and to determine the workload of working muscles. Objectives Considering the consistent number of studies on the application of muscle oximetry in sports science published over the last 5 years, the objectives of this updated systematic review were to highlight the applications of muscle oximetry in the assessment of skeletal muscle oxidative performance in sports activities and to emphasize how this technology has been applied to exercise and training over the last 5 years. In addition, some recent instrumental developments will be briefly summarized. Methods Preferred Reporting Items for Systematic Reviews guidelines were followed in a systematic fashion to search, appraise and synthesize existing literature on this topic. Electronic databases such as Scopus, MEDLINE/PubMed and SPORTDiscus were searched from March 2017 up to March 2023. Potential inclusions were screened against eligibility criteria relating to recreationally trained to elite athletes, with or without training programmes, who must have assessed physiological variables monitored by commercial oximeters or NIRS instrumentation. Results Of the identified records, 191 studies regrouping 3435 participants, met the eligibility criteria. This systematic review highlighted a number of key findings in 37 domains of sport activities. Overall, NIRS information can be used as a meaningful marker of skeletal muscle oxidative capacity and can become one of the primary monitoring tools in practice in conjunction with, or in comparison with, heart rate or mechanical power indices in diverse exercise contexts and across different types of training and interventions. Conclusions Although the feasibility and success of the use of muscle oximetry in sports science is well documented, there is still a need for further instrumental development to overcome current instrumental limitations. Longitudinal studies are urgently needed to strengthen the benefits of using muscle oximetry in sports science.

show abstract

Multiple-day high-dose beetroot juice supplementation does not improve pulmonary or muscle deoxygenation kinetics of well-trained cyclists in normoxia and hypoxia

Cited by 4 publications

References 63 publications

Effects of Dietary Nitrate Supplementation on Performance and Muscle Oxygenation during Resistance Exercise in Men

Effects of Dietary Nitrate Supplementation on Performance and Muscle Oxygenation during Resistance Exercise in Men

The effects of nitrate ingestion on high-intensity endurance time-trial performance: A systematic review and meta-analysis

Muscle Oximetry in Sports Science: An Updated Systematic Review

Contact Info

Product

Resources

About