Multiple, Clustered Dermatofibroma: A Rare Clinical Variant of Dermatofibroma

Soon, Seaver L.; Howard, Amy K.; Washington, Carl V.

doi:10.1177/120347540300700604

Cited by 16 publications

(15 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…A relevant diagnosis when considering PMTI is the rare condition “multiple clustered dermatofibromas,” which has been reported predominantly in children and young adults . This presents as a cluster of small dermatofibromas that extend to involve an area typically larger than 5 cm and most often is located on the hip or upper leg.…”

Section: Discussionmentioning

confidence: 99%

Plaque‐Like Myofibroblastic Tumor: Report of Three Cases

Marqueling

Dasher

Friedlander

et al. 2013

Pediatric Dermatology

View full text Add to dashboard Cite

Plaque-like myofibroblastic tumor of infancy (PMTI) was first reported in 2007. The first two cases described large, plaque-like tumors presenting in infancy with microscopic features consistent with dermatofibroma but with immunohistochemical features of myofibrocytic lineage. We present three additional cases of PMTI, the first cases reported since the initial two cases, and describe additional clinical features of this condition, including presentation in early childhood as opposed to infancy, development of ulceration, and aggressive growth. We propose shortening the name of this condition to plaque-like myofibroblastic tumor because presentation can occur in infancy or in early childhood.

show abstract

Section: Discussionmentioning

confidence: 99%

Plaque‐Like Myofibroblastic Tumor: Report of Three Cases

Marqueling

Dasher

Friedlander

et al. 2013

Pediatric Dermatology

View full text Add to dashboard Cite

show abstract

“…1 Multiple lesions are described in patients with both normal and altered immune function but are more often associated with diseases requiring immunosuppressive therapy including human immunodeficiency virus infection, myasthenia gravis, atopic dermatitis, systemic lupus erythematosus and diabetes. 2,3 Multiple clustered dermatofibroma (MCDF) is a very rare variant with only 12 descriptions in the literature. MCDF appears as a well-demarcated plaque composed of individual reddish to brown grouped papules.…”

mentioning

confidence: 99%

Multiple clustered dermatofibroma: case report and review of the literature

Gershtenson¹,

Krunic²,

Chen³

2010

J Cutan Pathol

View full text Add to dashboard Cite

The presence of multiple dermatofibromas is rare and is defined as more than 15 lesions. Multiple clustered dermatofibroma (MCDF) is a distinct entity with only 12 reported cases in the literature. MCDF occurs in healthy individuals of both sexes in the first to third decades on the lower half of the body and portends an excellent prognosis. On histology, MCDF is consistent with benign dermatofibromas. We report a 31-year-old healthy Hispanic woman with a 14-year history of slowly progressive MCDF located on her right hip initially misdiagnosed as dermatofibrosarcoma protuberans. We believe this case represents the 13th report of MCDF in the literature and the second from North America.

show abstract

“…The clinical characteristics of this case shows all the features common to all cases of this variant form of DF previously reported, these being, occurrence in healthy individual in the second decade, slowly progressive evolution increasing over many years [9,10] and DF typical lesions. The location on the left buttock is also quite typical, and 2 biopsies on different places were consistent with dermatofibroma [11,12] . In our case the patient was asymptomatic, with pericardial cyst accidentally identified.…”

Section: Discussionmentioning

confidence: 75%

Multiple clustered dermatofibroma associated with asymptomatic pericardial cyst

Brzeziński

Kazlouskaya

Bimbi³

2017

J Surg Dermatol

View full text Add to dashboard Cite

Multiple clustered dermatofibroma (MCDF) is an unusual variant of dermatofibroma (DF) presentation, localized on one segment of the body. Multiple dermatofibroma is a term for when there are more than 15 dermatofibromas, which in itself is already a rare condition. The dermatofibromas usually appear in younger adults and are predominantly located on lower parts of the body. No associations, except one case with pulmonary hypertension, were described in patients with MCDF. Herein we present another case of this rare complaint in a 58 year old female with clustered lesions on the thigh. Pericardial cyst was identified in our patient during routine chest X-ray and the patient is asymptomatic. MCDFs do not usually require treatment unless requested by the patient for cosmetic reason. This variant of MCDF, which is neither congenital nor eruptive, is extraordinarily rare, with only 13 cases reported. Further reports may identify possible associations of MCDF.Keywords: Dermatofibroma; histiocytomas; pericardial cyst Citation: Brzezinski P, Kazlouskaya V, Bimbi C. Multiple clustered dermatofibroma associated with asymptomatic pericardial cyst.

show abstract

Multiple, Clustered Dermatofibroma: A Rare Clinical Variant of Dermatofibroma

Abstract: Despite an active early growth phase, MCDF appears to follow a benign clinical course, with no report of sarcomatous transformation at up to 20 years followup.

Cited by 16 publications

References 16 publications

Plaque‐Like Myofibroblastic Tumor: Report of Three Cases

Plaque‐Like Myofibroblastic Tumor: Report of Three Cases

Multiple clustered dermatofibroma: case report and review of the literature

Multiple clustered dermatofibroma associated with asymptomatic pericardial cyst

Contact Info

Product

Resources

About