Multiple cerebral infarctions with severe multi-organ dysfunction following multiple wasp stings

Wani, Mudassir Maqbool; Saleem, Sheikh; Verma, Sawan; Yousuf, Irfan; Asimi, Ravouf; Ra, Daga; Shah, Irfan; Aejaz,

doi:10.4103/0972-2327.128581

Cited by 11 publications

(4 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Neurologic manifestations are rare in bee venom poisoning 3, 4, 5, 6, 7, 8. Stroke and multi-organ dysfunction after bee stings are extremely rare 9 . To the best of our knowledge this is the second ever case report of stroke after bee sting.…”

Section: Introductionmentioning

confidence: 80%

Acute ischemic stroke and severe multiorgan dysfunction due to multiple bee stings

Güzel

Akar

Erenler

et al. 2016

Turkish Journal of Emergency Medicine

View full text Add to dashboard Cite

Various manifestations after bee sting have been described. Local reactions, such as pain, wheal, flare, edema and swelling, are common and generally self-limiting. Uncommonly manifestations like vomiting, diarrhea, dyspnea, generalized edema, acute renal failure, anaphylactic shock, myocardial infarction, hypotension, collapse, pulmonary hemorrhage, acute hemorrhagic pancreatitis, and atrial fibrillation may occur. We report a 59 year-old man who sustained ischemic stroke and multi-organ dysfunction following multiple bee stings.

show abstract

Section: Introductionmentioning

confidence: 80%

Acute ischemic stroke and severe multiorgan dysfunction due to multiple bee stings

Güzel

Akar

Erenler

et al. 2016

Turkish Journal of Emergency Medicine

View full text Add to dashboard Cite

show abstract

“…Several serious neurological manifestations and cerebral lesions of Hymenoptera stings have been also reported. Encephalitis 122, peripheral neuritis 123, optic neuropathy 124, myasthenia gravis 125, cerebral infraction 126, acute inflammatory polyradiculopathy indistinguishable from Guillan-Barre 127, acute disseminated encephalomyelitis 128 and encephalo-myelo-radiculoneuritis 129 all have been reported. Means et al 130 reported a case with relapsing and progressive bilateral weakness and numbness of arms and legs followed by Vespula pennsylvanica stings.…”

Section: Clinical Studies With Different Insectsmentioning

confidence: 99%

A review on Respiratory allergy caused by insects

Kausar¹

2018

Bioinformation

View full text Add to dashboard Cite

Hypersensitivity or allergy encompasses a wide range of immunological reactions that generally have adverse consequences involving one or many organ systems of the body. Allergens are usually glycoprotein or chemically complex low molecular weight substances. The common allergens include pollen, fungal spores, house dust mite and house dust, animal danders, drugs, foods, insect emanations, and detritus, etc. Information on the role of insects in respiratory allergy is increasing in the literature. There are about 30 million living species of insects. These insects can broadly be classified as stinging insects, biting insects and non-stinging and non-biting insects. All materials form insets namely wings, scales, saliva; dried feces and venom can cause allergic diseases, such as rhinitis, conjunctivitis, asthma and urticaria. There are wide varieties of insects such as moths, butterflies, bees, wasps, hornets, yellow jackets, flies, beetles, cockroaches, and mosquitoes. Exposure to emanations and detritus of these insects may lead to several allergies in some genetically predisposed individuals. Therefore, it is of interest to review allergies caused by various insect’s stings and bites and their adverse effect on the human body.

show abstract

“…2 One reported case of massive wasp stings presented with disseminated intravascular coagulation (DIC), stroke, and acute renal failure. 3 Patients experiencing insect sting-related anaphylactic shock have also exhibited clinical and laboratory features of a severe acute generalized fibrinolytic state, but not DIC. 4 The distinctive manifestation of coagulopathy in patients stung by wasps ( Vespa affinis, common species in Xiamen, Fujian, China), with severe coagulation abnormalities, has been observed (case collections from our hospital).…”

Section: Introductionmentioning

confidence: 99%

Hyperendogenous Heparinization Suggests a Guideline for the Management of Massive Wasp Stings in Two Victims

Lai¹,

Tian²,

Zhang³

et al. 2021

Wilderness & Environmental Medicine

View full text Add to dashboard Cite

Bees and wasps (order Hymenoptera) are commonly encountered worldwide and often deliver defensive stings when in contact with humans. Massive envenomation resulting from >50 stings causes a toxic reaction and life-threatening complications that typically result in rhabdomyolysis and disseminated intravascular coagulation. Two male patients who were stung over 80 times by wasps experienced severe coagulation abnormality. Consecutive examination by thromboelastography (TEG) guided by heparinase treatment during their hospitalization evidenced heparin-like coagulation dysfunction despite no clinical use of heparin-like substances. Numerous tests were also conducted to confirm whether the coagulation abnormalities could be attributed to hyperendogenous heparinization and allergic reaction, rhabdomyolysis, and vascular endothelial cell injury without apparent disseminated intravascular coagulation, which might all be affected by the production of endogenous heparin. The reduced coagulation potential caused by hyperendogenous heparinization was associated with the binding of antithrombin and the activation of fibrinolysis. In addition, TEG-identified coagulopathy was moderated using protamine for heparin neutralization. The massively envenomed patients survived and were discharged after completion of medical care. We also review clinical manifestations from other published case reports, including topical treatment. Our study provides clinical evidence and guidance for diagnosis via TEG and appropriate intervention with protamine for patients with massive wasp envenomation.

show abstract

Multiple cerebral infarctions with severe multi-organ dysfunction following multiple wasp stings

Cited by 11 publications

References 3 publications

Acute ischemic stroke and severe multiorgan dysfunction due to multiple bee stings

Acute ischemic stroke and severe multiorgan dysfunction due to multiple bee stings

A review on Respiratory allergy caused by insects

Hyperendogenous Heparinization Suggests a Guideline for the Management of Massive Wasp Stings in Two Victims

Contact Info

Product

Resources

About