Multiple Biomarkers at Admission Significantly Improve the Prediction of Mortality in Patients Undergoing Primary Percutaneous Coronary Intervention for Acute ST-Segment Elevation Myocardial Infarction

Damman, Peter; Beijk, Marcel A.M.; Kuijt, Wichert J.; Verouden, Niels; Geloven, Nan van; Henriques, José P.S.; Baan, Jan; Vis, Marije M.; Meuwissen, Martijn; Straalen, Jan P. van; Fischer, Johan; Koch, Karel T.; Piek, Jan J.; Tijssen, Jan G.P.; Winter, Robbert J. de

doi:10.1016/j.jacc.2010.06.053

Cited by 90 publications

(64 citation statements)

References 25 publications

(19 reference statements)

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“…The proposed scoring method is not widely accepted, although there are studies involving a similar method for patients with acute coronary syndrome. 31 When all scores were set uniformly as 0, 1, or 2 in every degree of severity, C-indices of this scoring method for predicting allcause mortality (0.825 and 0.828, respectively) and cardiovascular mortality (0.773 and 0.778, respectively) were similar to the current scoring method (data not shown). Further research is necessary to develop an optimal scoring method.…”

Section: Disclosuresmentioning

confidence: 74%

Multimarker Approach to Risk Stratification for Long-Term Mortality in Patients on Chronic Hemodialysis

Ishii

Kitagawa

Kuno

et al. 2015

Circ J

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Section: Disclosuresmentioning

confidence: 74%

Multimarker Approach to Risk Stratification for Long-Term Mortality in Patients on Chronic Hemodialysis

Ishii

Kitagawa

Kuno

et al. 2015

Circ J

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“…The clinical significance of renal function and NT-proBNP measurement for prognosis for patients with CVD has been investigated by many prior studies; however, the findings of these studies only reflect the predictive value of NT-proBNP level and renal function for clinical prognosis [4,9,23,24]. In contrast, this study focused on evaluating different effects and optimal NT-proBNP cut-off values for prognostic prediction in CAD patients with various eGFRs.…”

Section: Discussionmentioning

confidence: 99%

The impact of renal function on the prognostic value of N-terminal pro–B-type natriuretic peptide in patients with coronary artery disease

Chen¹,

Li²,

Ou³

et al. 2020

Cardiol J.

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“…[23][24][25] Notably, the impairment in reference vessel CFVR resulted primarily from a low hyperemic APV in the presence of high hyperemic microvascular resistance, in combination with a high baseline APV in the presence of a low baseline microvascular resistance in patients with an abnormal reference vessel CFVR (Table 3).…”

Section: Clinical and Procedural Characteristics According To Referenmentioning

confidence: 99%

Impact of Coronary Microvascular Function on Long-term Cardiac Mortality in Patients With Acute ST-Segment–Elevation Myocardial Infarction

Hoef

Bax

Meuwissen

et al. 2013

Circ: Cardiovascular Interventions

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Background-Microvascular function is increasingly being recognized as an important marker of risk in coronary artery disease, and may be accurately assessed by intracoronary Doppler flow velocity measurements. In the setting of STsegment-elevation myocardial infarction there are limited data regarding the prognostic value of microvascular function in both infarct-related and reference coronary arteries for long-term clinical outcome. We sought to determine the prognostic value of microvascular function, as assessed by Doppler flow velocity measurements, for cardiac mortality after primary percutaneous coronary intervention for acute ST-segment-elevation myocardial infarction. Methods and Results-Between April 1997 and August 2000, we included 100 consecutive patients with a first anterior wall ST-segment-elevation myocardial infarction. Immediately after primary percutaneous coronary intervention, intracoronary Doppler flow velocity was measured in the infarct-related artery, to determine coronary flow velocity reserve (CFVR), diastolic deceleration time, and the presence of systolic retrograde flow, as well as in a reference vessel to determine reference vessel CFVR. The primary end point was cardiac mortality at 10-year follow-up. Complete follow-up was obtained in 94 patients (94%). At 10-year follow-up, cardiac mortality amounted to 14%. Cardiac mortality amounted to 5% when reference vessel CFVR was normal (≥2.1), in contrast to 31% when abnormal (<2.1; P=0.001). Reference vessel CFVR <2.1 was associated with a 4.09 increase in long-term cardiac mortality hazard after multivariate adjustment for identified predictors for cardiac mortality (hazard ratio, 4.09; 95% confidence interval, 1.18-14.17; P=0.03) Conclusions-Microvascular dysfunction, measured by reference vessel CFVR determined after primary percutaneous coronary intervention for acute anterior wall ST-segment-elevation myocardial infarction is associated with a significantly increased long-term cardiac mortality. (Circ Cardiovasc Interv. 2013;6:207-215.)

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Multiple Biomarkers at Admission Significantly Improve the Prediction of Mortality in Patients Undergoing Primary Percutaneous Coronary Intervention for Acute ST-Segment Elevation Myocardial Infarction

Cited by 90 publications

References 25 publications

Multimarker Approach to Risk Stratification for Long-Term Mortality in Patients on Chronic Hemodialysis

Multimarker Approach to Risk Stratification for Long-Term Mortality in Patients on Chronic Hemodialysis

The impact of renal function on the prognostic value of N-terminal pro–B-type natriuretic peptide in patients with coronary artery disease

Impact of Coronary Microvascular Function on Long-term Cardiac Mortality in Patients With Acute ST-Segment–Elevation Myocardial Infarction

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