Multiple adenomas of the thyroid occurring 20 years after successful radiotherapy for neuroblastoma in the cervical lymph-nodes

McKenzie, C. G.; Hope-Stone, H. F.

doi:10.1259/0007-1285-48-576-1028

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1979

1987

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Cited by 6 publications

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Thyroid neoplasia following irradiation for medulloblastoma. Report of two cases

Roggli

Estrada

Fechner

1979

Cancer

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Thyroid neoplasms occurred in two patients 14 and 18 years after treatment with radiation for medulloblastoma. One patient has a papillary cancer and the other patient had multiple adenomas and a Hurthle cell adenoma. In addition, the latter case had foci of hyperplasia plus a microfollicular transformation, which has not been described in association with prior thyroid irradiation. The radiation doses delivered to the thyroid through posterior cervical spinal ports (2000--3000 roentgens) fall within the upper range of radiation dosage associated with induction of neoplastic changes within the thyroid.

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