During the last few decades, wireless communication technologies and services have radically changed the way we live and interact at the personal, social, local and global levels.Such changes were mainly driven by the continuous emergence of innovative wireless communication services and products. These services and products represents a direct upshot of enduring research outcomes within the area. Nevertheless, the blessing of such innovation was accompanied by extremely high demands in forms of data traffic, per-user transmission rate, minimum transmission delay and in the number of wireless devices per unit area.Tackling these issues through cellular network densification was faced by many technical issues related to high interference levels, tedious user scheduling processes, and complicated network resource allocation algorithms. Trying to address these imperative technical issues in future wireless networks, this thesis develops several innovative enabling techniques for massive wireless multiple access. Specifically, we commence this work by introducing a new concept of partial spectrum overlapping among active users equipment (UEs). The proposed scheme represents a trade-off between fully orthogonal multiple access schemes (e.g. time division multiple access [TDMA], frequency division multiple access (FDMA) and orthogonal frequency division multiple access (OFDMA)) and that of non-orthogonal multiple access (NOMA). Second, we develop several innovative dynamic cell-free network architectures that support massive wireless connectivity through adaptive access points (APs)/base stations (BSs) coordination and/or cooperation. The proposed network models are then evaluated under different state-of-the-art enabling wireless techniques such as millimeter wave (mmWave) channel links and massive multiple-input multiple-output (mMIMO) sys-ACKNOWLEDGMENT Acknowledgement is due to the University of Manitoba for giving me this precious opportunity to resume my PhD degree. I would like to express deep gratefulness and appreciation to my Thesis advisor, Prof. Ekram Hossain for his continuous help, guidance, and encouragement throughout the course of this work. He spent a lot of his precious time helping me