Multimodal Wearable Sensor Sheet for Health-Related Chemical and Physical Monitoring

Abstract

Continuous multiple data health monitoring has high potential to detect abnormal conditions or early stages of diseases in the future. To monitor a continuous small vital signal, one of the promising architectures is an attachable flexible multimodal sensor system, which can detect multiple health conditions from the skin surface. Recent breakthroughs have realized continuous sweat chemicals or physical conditions using flexible sensors. However, multimodal sensor integration to monitor chemical and physical information simultaneously and precisely is still a challenge. In this study, we present a multimodal wearable sensor sheet, which allows us to monitor sweat glucose, electrocardiograms, and skin temperature. Furthermore, to prevent the accumulation of glucose on the sensor surface for precise monitoring, a fluidic channel is also integrated to refresh the sweat from the sensor surface, resulting in the precise measurement of chemical substances in real time. This multimodal and flexible sensor platform takes a significant step toward realizing wearable healthcare applications to diagnose the early stages of diseases in advance.

End-to-end design of wearable sensors

“…Biocompatibility constraints of the device materials, poor signal-to-noise ratio (SNR) and complex integration of the transduction elements with other structures or electronics within the wearable have so far limited the number of detectable biologically relevant analytes, resulting in the relatively slow development of wearable sensors for biochemical analysis 1 , 3 , 4 . Transduction modes can also be combined for multimodal analysis to improve the performance or range of capabilities available for continuous physiological monitoring 8 , 10 , 102 , 103 .…”

3D Waterproof MXene‐Based Textile Electronics for Physiology and Motion Signals Monitoring

“…Wenjing Fan, Cheng Li,* Wei Li, and Jin Yang DOI: 10.1002/admi.202102553 trical properties while maintaining the wearing comfort has been a great challenge because most devices with excellent electrical properties need to be attached to the skin with packaging tapes or bandage, limiting their flexibility. [15,16] Textile electronics, a special flexible device, are more promising for human health and motion monitoring because of their unique characteristics such as softness, portability, and air permeability. To date, there have been a large number of studies on textile electronics used to detect human temperature, [17][18][19][20] pulse, [21][22][23] respiration, [24][25][26] sweat, [27,28] body movement, [29][30][31] and so on, which may become a substitute for thin-film sensors.…”

Wearable Sensing Systems for Monitoring Mental Health

“…Wearable ECG sensors with advanced materials have a great potential for the continuous monitoring of cardiac activities, and there are various types of ECG sensors. Figure 2 B shows a typical patch-type ECG sensor, composed of three Ag electrodes that are screen-printed on a flexible (but not soft) polymer (poly(ethylene terephthalate)) substrate and covered by commercially available gel sheets (total thickness: few mm) for conformal contact with skin [ 15 ]. This sensor was attached on a skin surface of a subject with the aid of a medial glue sheet and recorded ECG signals continuously while the subject did physical exercise.…”