Multimodal transcranial magnetic stimulation: Using concurrent neuroimaging to reveal the neural network dynamics of noninvasive brain stimulation

Reithler, Joel; Peters, Judith C.; Sack, Alexander T.

doi:10.1016/j.pneurobio.2011.04.004

Cited by 103 publications

(80 citation statements)

References 192 publications

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“…If true, this would invalidate the interpretation of our data as revealing a behaviorally relevant contribution of low-level visual areas to skill consolidation in the earliest phases of learning. Remote activation changes via TMS have been described in several domains (Bestmann et al, 2004;Ruff et al, 2006;Sack et al, 2007; for review, see Reithler et al, 2011) and could have extended from V1 into V2 or V3. Nevertheless, significant behaviorally relevant remote effects of TMS to date have only been described in the top-down direction by direct stimulation of higher-order areas (Ruff et al, 2006).…”

Section: Discussionmentioning

confidence: 99%

Posttraining Transcranial Magnetic Stimulation of Striate Cortex Disrupts Consolidation Early in Visual Skill Learning

et al. 2012

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Practice-induced improvements in skilled performance reflect "offline " consolidation processes extending beyond daily training sessions. According to visual learning theories, an early, fast learning phase driven by high-level areas is followed by a late, asymptotic learning phase driven by low-level, retinotopic areas when higher resolution is required. Thus, low-level areas would not contribute to learning and offline consolidation until late learning. Recent studies have challenged this notion, demonstrating modified responses to trained stimuli in primary visual cortex (V1) and offline activity after very limited training. However, the behavioral relevance of modified V1 activity for offline consolidation of visual skill memory in V1 after early training sessions remains unclear. Here, we used neuronavigated transcranial magnetic stimulation (TMS) directed to a trained retinotopic V1 location to test for behaviorally relevant consolidation in human low-level visual cortex. Applying TMS to the trained V1 location within 45 min of the first or second training session strongly interfered with learning, as measured by impaired performance the next day. The interference was conditional on task context and occurred only when training in the location targeted by TMS was followed by training in a second location before TMS. In this condition, high-level areas may become coupled to the second location and uncoupled from the previously trained low-level representation, thereby rendering consolidation vulnerable to interference. Our data show that, during the earliest phases of skill learning in the lowest-level visual areas, a behaviorally relevant form of consolidation exists of which the robustness is controlled by high-level, contextual factors.

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Section: Discussionmentioning

confidence: 99%

Posttraining Transcranial Magnetic Stimulation of Striate Cortex Disrupts Consolidation Early in Visual Skill Learning

et al. 2012

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“…This work provides further evidence for the important relationship between the GABA modulation and motor learning, and, indeed, extends this to show a relationship between the capacity for GABA modulation and motor learning. Several recent reviews have focused on the use of NIBS combined with neuroimaging techniques and the reader is directed to these for further information (Dayan, Censor, Buch, Sandrini, & Cohen, 2013;Reithler, Peters, & Sack, 2011;Saiote, Turi, Paulus, & Antal, 2013;Siebner et al, 2009;Venkatakrishnan & Sandrini, 2012).…”

Section: How Do We Investigate Nibs-induced Plasticity?mentioning

confidence: 99%

Non-invasive induction of plasticity in the human cortex: Uses and limitations

Vallence

Ridding

2014

Cortex

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After the embargo period via non-commercial hosting platforms such as their institutional repository  via commercial sites with which Elsevier has an agreement In all cases accepted manuscripts should: link to the formal publication via its DOI  bear a CC-BY-NC-ND license -this is easy to do, click here to find out how  if aggregated with other manuscripts, for example in a repository or other site, be shared in alignment with our hosting policy  not be added to or enhanced in any way to appear more like, or to substitute for, the published journal article AbstractThe last couple of decades have seen the development of a number of non-invasive brain stimulation (NIBS) techniques that are capable of inducing short-lasting plasticity in the human cortex. Importantly, the induction of lasting plastic changes can, under some conditions, reversibly modify behaviour and interact with learning.These techniques have provided novel opportunities to study human cortical plasticity and examine the role of cortical regions in behaviour. In this review we briefly summarise current NIBS techniques, outline approaches to characterise and quantify cortical plastic change, and describe mechanisms that are implicated in the induced

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“…The direct impact of a TMS is limited to a patch of cortex of a few square centimetres and the induced field falls off exponentially with distance. The effective penetration depth of TMS is estimated to be ~ 2 cm [59]. The intensity of the stimuli can be controlled by changing the current intensity flowing in the coil, thus changing the magnitude of the induced magnetic field and of the secondarily induced electrical field.…”

Section: Examples Of Surgeries Requiring Mep Are For Tumors Located Amentioning

confidence: 99%

Functional MRI, Diffusion Tensor Imaging, Magnetic Source Imaging and Intraoperative Neuromonitoring Guided Brain Tumor Resection in Awake and Under General Anaesthesia

Idris¹,

Hassan²,

Mustapha³

et al. 2013

Clinical Management and Evolving Novel Therapeutic Strategies for Patients With Brain Tumors

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Multimodal transcranial magnetic stimulation: Using concurrent neuroimaging to reveal the neural network dynamics of noninvasive brain stimulation

Cited by 103 publications

References 192 publications

Posttraining Transcranial Magnetic Stimulation of Striate Cortex Disrupts Consolidation Early in Visual Skill Learning

Posttraining Transcranial Magnetic Stimulation of Striate Cortex Disrupts Consolidation Early in Visual Skill Learning

Non-invasive induction of plasticity in the human cortex: Uses and limitations

Functional MRI, Diffusion Tensor Imaging, Magnetic Source Imaging and Intraoperative Neuromonitoring Guided Brain Tumor Resection in Awake and Under General Anaesthesia

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