Multimodal Imaging of Serpiginous Choroiditis

Khan, Hashim Ali; Shahzad, Muhammad Aamir

doi:10.1097/opx.0000000000001015

Cited by 16 publications

(16 citation statements)

References 30 publications

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“…OCTA of choriocapillaris on active lesions shows clearly demarcated flow-deficit areas that correspond precisely to the hypofluorescent lesions on ICGA [82,83]. Conversely, inactive lesions demonstrate some detectable flow within the areas of flow void, indicating deeper medium-to-large choroidal vessels existence and choriocapillaris loss, better detected on OCTA than on ICGA [23,84,85].…”

Section: Punctate Inner Choroidopathymentioning

confidence: 83%

“…During the healing process, as a result of the choriocapillaris atrophy in some patients, medium-to-large choroidal vessels may be visualized in choriocapillaris zone on en face OCTA [89]. Vascular abnormalities, including nonneovascular tufts, tangled vessels and neovascular membranes may also be assessed with OCTA, which clearly demarcates the involvement of various retinochoroidal layers [85,89].…”

Section: Tuberculosismentioning

confidence: 99%

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Optical coherence tomography angiography in uveitis

Tranos¹,

Karasavvidou

Gkorou³

et al. 2019

J Ophthal Inflamm Infect

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Before the introduction of optical coherence tomography angiography (OCTA) in the early 2000s, dye-based angiography was considered the "gold standard" for the diagnosis and monitoring of ocular inflammation. OCTA is a novel technique, which demonstrates capillary networks based on the amount of light returned from moving blood cells, providing further information on pathophysiological changes in uveitis. The aim of this review is to describe the basic principles of OCTA and its application to ocular inflammatory disorders. It particularly emphasizes on its contribution not only in the diagnosis and management of the disease but also in the identification of possible complications, comparing it with fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA). Although the advent of OCTA has remarkably enhanced the assessment of uveitic entities, we highlight the need for further investigation in order to better understand its application to these conditions.

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Section: Punctate Inner Choroidopathymentioning

confidence: 83%

Section: Tuberculosismentioning

confidence: 99%

Optical coherence tomography angiography in uveitis

Tranos¹,

Karasavvidou

Gkorou³

et al. 2019

J Ophthal Inflamm Infect

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“…Khan and Shahzad14 reported a case of active lesions of SC showing loss of choriocapillaris homogeneity at OCT-A. Also, Ahn et al 15 have demonstrated decreased vascularity of the choriocapillaris in an active lesion using OCT-A.…”

Section: Discussionmentioning

confidence: 97%

“…Also, Ahn et al 15 have demonstrated decreased vascularity of the choriocapillaris in an active lesion using OCT-A. They hypothesised that the destruction of the choriocapillaris may lead to photoreceptor disruption, then to an important visual loss 14. See comment in PubMed Commons below.…”

Section: Discussionmentioning

confidence: 99%

Swept-source optical coherence tomography angiography in serpiginous choroiditis

et al. 2017

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“…Until now, there are only case reports concerning OCTA and one case series encompassing 3 patients in SC [15]. Therefore, the aim of this study is to describe these ndings in greater extent and compare them to known diagnostic tools, such as FA, ICGA, fundus auto uorescence (FAF), and enhanced depth imaging optical coherence tomography (EDI-OCT) [16][17][18][19][20][21][22][23].…”

Section: Introductionmentioning

confidence: 99%

Optical Coherence Tomography Angiography (OCTA) findings in Serpiginous Choroiditis

Macedo

Pohlmann

Lenglinger

et al. 2020

Preprint

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Abstract Background. To describe changes in the retina/choroid in patients with Serpiginous Choroiditis (SC) by Optical Coherence Tomography Angiography (OCTA) in a multimodal imaging approach. Methods. Prospective, monocentric study of 24 eyes of 12 consenting patients diagnosed with SC, who underwent OCTA, which was analyzed and compared to other methods such as enhanced depth imaging-OCT, fluorescein angiography, indocyanine green angiography, and fundus autofluorescence. Results. The study group consisted of 9 patients with peripapillary SC, 1 macular SC, and 2 atypical cases. All eyes presented an inactive SC confirmed by standard imaging. OCTA demonstrated the lesions tridimensionally in great detail. There was no difference in the angioarchitecture among the 3 forms of SC. A loss of the choriocapillaris/retinal pigment epithelium left a “window-defect”, where the vessels of larger caliber of the choroid became recognizable and their appearance inverted (“white-on-black”). A relationship between the presence of segmentation errors (SE) in the slabs and low visual acuity was established with a one-way ANOVA. Conclusions. OCTA was able to non-invasively assess vascular lesions of the choroid/retina in patients with SC with a high degree of correlation to other diagnostic modalities. Consequent long-term assessments could lead to a better understanding of disease progression.

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Multimodal Imaging of Serpiginous Choroiditis

Cited by 16 publications

References 30 publications

Optical coherence tomography angiography in uveitis

Optical coherence tomography angiography in uveitis

Swept-source optical coherence tomography angiography in serpiginous choroiditis

Optical Coherence Tomography Angiography (OCTA) findings in Serpiginous Choroiditis

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