Purpose:
Segmentation of cardiac medical images, an important step in measuring cardiac function, is usually performed either manually or semi-automatically. Fully automatic segmentation of the left ventricle (LV), the right ventricle (RV) as well as the myocardium of 3D magnetic resonance (MR) images throughout the entire cardiac cycle (4D), remains challenging. This study proposes a deformable-based segmentation methodology for efficiently segmenting 4D (3D+t) cardiac MR images.
Methods:
The proposed methodology first used the Hough transform and the local Gaussian distribution method (LGD) to segment the LV endocardial contours from cardiac MR images. Following that a novel level set-based shape prior method was applied to generate the LV epicardial contours and the RV boundary.
Results:
This automatic image segmentation approach has been applied to studies on 17 subjects. The results demonstrated that the proposed method was efficient compared to manual segmentation, achieving a segmentation accuracy with average Dice values of 88.62±5.47%, 87.35±7.26%, and 82.63±6.22% for the LV endocardial, LV epicardial and RV contours, respectively.
Conclusions:
We have presented a method for accurate LV and RV segmentation. Compared to three existing methods, the proposed method can successfully segment the LV and yields the highest Dice value. This makes it an option for clinical assessment of the volume, size and thickness of the ventricles.