Multilayer films based on host–guest interactions between biocompatible polymers

Abstract

Multilayer films are formed using host-guest interaction between two derivatized chitosans, one, with beta-cyclodextrin cavities and the other with adamantyl moieties.

Turbidity diagrams of polyanion/polycation complexes in solution as a potential tool to predict the occurrence of polyelectrolyte multilayer deposition

“…The layer-by-layer (LBL) deposition can rely on ESA as well as on the self-assembly of molecules carrying complementary functionalities, for instance polymers carrying hydrogen donor or acceptor moieties [19][20][21][22]. Charge transfer [23,24] and host-guest interactions [25] can also be used to build films using the layer-by-layer concept. Multilayer films can be obtained from two multifunctional molecules A and B provided that the functionality of A overcompensates that of B during the alternate adsorption.…”

“…This film growth regime is by far the most common, the combination of poly(sodium-4-styrene sulfonate) (PSS) and poly(allylamine hydrochloride) (PAH) at ambient temperature being one of the most representative examples [4,25,44].…”

Host-Guest Chemistry in Layer-by-Layer Assemblies Containing Calix[n]arenes and Cucurbit[n]urils: A Review

“…On the other hand, the LbL film decomposed instantly upon adding 1 mg·mL −1 adamantane (Ad) as a result of the competitive binding of Ad to the cavity of the CB [8]. CB [8]-based LbL films are more stable than similar LbL films linked with cyclodextrin [66,67] It is known that CB [8] forms a stable 1:1:1 ternary complex with electron-rich and electron-deficient molecules, in which the ternary complex is stabilized through host-guest complexation, as well as charge transfer interactions [64]. In fact, LbL films comprising PEIs covalently modified with electron-rich indole (PEI-ID) and electron-deficient methyl viologen moieties (PEI-MV) have been prepared using CB [8] as the binder [65].…”

“…On the other hand, the LbL film decomposed instantly upon adding 1 mg·mL −1 adamantane (Ad) as a result of the competitive binding of Ad to the cavity of the CB [8]. CB [8]-based LbL films are more stable than similar LbL films linked with cyclodextrin [66,67] A supramolecular pseudo-polycation composed of naphthalene-bearing dextran (NpD), MV, and CB [8] has been utilized as a cationic component for the construction of LbL films with poly(acrylic Polymers 2018, 10, 130 7 of 15 acid) (PAA) through electrostatic affinity [68]. The (PAA/NpD + MV + CB [8]) n LbL films decomposed in the presence of Ad or Na 2 S 2 O 4 as a result of the competitive binding of Ad to CB [8] or a reduction of MV by Na 2 S 2 O 4 .…”

Multilayered thin films from poly(amido amine)s for controlled delivery

“…Addition of chelating agents disrupts the metal ion coordination bonds and thus leads to film disruption. Similarly, multilayer fabricated from alternating layers of cyclodextrin-and adamantane-grafted chitosan were shown to disassemble upon addition of molecules that compete with this host-guest interaction [233].…”