2014
DOI: 10.1038/nnano.2014.38
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Multifunctional wearable devices for diagnosis and therapy of movement disorders

Abstract: Wearable systems that monitor muscle activity, store data and deliver feedback therapy are the next frontier in personalized medicine and healthcare. However, technical challenges, such as the fabrication of high-performance, energy-efficient sensors and memory modules that are in intimate mechanical contact with soft tissues, in conjunction with controlled delivery of therapeutic agents, limit the wide-scale adoption of such systems. Here, we describe materials, mechanics and designs for multifunctional, wear… Show more

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Cited by 1,271 publications
(645 citation statements)
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“…Single crystalline silicon strain gauges on soft elastomer exhibit a linear relationship between strain and relative resistance changes with fast response times 21 . These sensors have been previously utilized to detect motion across various anatomical locations, such as the wrist 22 and fingers 23 . In addition, stretchable metal and single crystalline silicon temperature sensors 12,24 fabricated on ultrathin substrates have been applied for temperature monitoring on human skin.…”
mentioning
confidence: 99%
“…Single crystalline silicon strain gauges on soft elastomer exhibit a linear relationship between strain and relative resistance changes with fast response times 21 . These sensors have been previously utilized to detect motion across various anatomical locations, such as the wrist 22 and fingers 23 . In addition, stretchable metal and single crystalline silicon temperature sensors 12,24 fabricated on ultrathin substrates have been applied for temperature monitoring on human skin.…”
mentioning
confidence: 99%
“…In human-computer interaction (HCI) studies, sensor-based technologies have been the focus of research on gesture recognition (Benoit, Allevard, Ukegawa, & Sawada, 2003;Lyons, Brashear, Westeyn, Kim, & Starner, 2007), wearable devices for remote health monitoring (Patel. Park, Bonato, Chan, & Rodgers, 2012;Son et al, 2014), and smart home systems (Kühnel et al, 2011).…”
Section: Sensorsmentioning
confidence: 99%
“…In the mechanical method, the ultrathin devices are generally peeled off from the polydimethylsiloxane (PDMS) stamps or parylene release layer by mechanical forces 8, 20, 21, 22, 23, 24. While in the chemical method, the devices are released by dissolving different sacrificial layers like polyvinyl alcohol (PVA)25, 26 or polymethyl methacrylate (PMMA)27, 28, 29 with the corresponding solvents. To avoid the fragile properties of the ultrathin substrate during mechanical peeling and the potential hazards to the devices during chemical etching, an easy, integrated and ecofriendly device transfer method need to be used.…”
mentioning
confidence: 99%