Multifunctional, Robust, and Porous PHBV—GO/MXene Composite Membranes with Good Hydrophilicity, Antibacterial Activity, and Platelet Adsorption Performance

Abstract

The limitations of hydrophilicity, strength, antibacterial activity adsorption performance of the biobased and biocompatible polymer materials, such as polyhydroxyalkanoates (PHAs), significantly restrict their wider applications especially in medical areas. In this paper, a novel composite membrane with high antibacterial activity and platelet adsorption performance was prepared based on graphene oxide (GO), MXene and 3-hydroxybutyrate-co-hydroxyvalerate (PHBV), which are medium-chain-length-copolymers of PHA. The GO/MXene nanosheets can uniformly inset on the surface of PHBV fibre and give the PHBV—GO/MXene composite membranes superior hydrophilicity due to the presence of hydroxyl groups and terminal oxygen on the surface of nanosheets, which further provides the functional site for the free radical polymerization of ester bonds between GO/MXene and PHBV. As a result, the tensile strength, platelet adsorption, and blood coagulation time of the PHBV—GO/MXene composite membranes were remarkably increased compared with those of the pure PHBV membranes. The antibacterial rate of the PHBV—GO/MXene composite membranes against gram-positive and gram-negative bacteria can reach 97% due to the antibacterial nature of MXene. The improved strength, hydrophilicity, antibacterial activity and platelet adsorption performance suggest that PHBV—GO/MXene composite membranes might be ideal candidates for multifunctional materials for haemostatic applications.

Degradation of Minocycline by the Adsorption–Catalysis Multifunctional PVDF–PVP–TiO2 Membrane: Degradation Kinetics, Photocatalytic Efficiency, and Toxicity of Products

“…The surface morphologies of the fiber mats were examined by field emission scanning electron microscopy (FE-SEM, Merlin, Jena, Germany) [ 22 ]. A transmission electron microscope (TEM, JEOL Ltd., Akishima, Japan) was operated at the electron accelerating voltage of 200 kV, the adhesive fibers on the copper wire were dried and observed in the electron microscope sample chamber [ 22 ].…”

“…The surface morphologies of the fiber mats were examined by field emission scanning electron microscopy (FE-SEM, Merlin, Jena, Germany) [ 22 ]. A transmission electron microscope (TEM, JEOL Ltd., Akishima, Japan) was operated at the electron accelerating voltage of 200 kV, the adhesive fibers on the copper wire were dried and observed in the electron microscope sample chamber [ 22 ]. An Alpha 300 M Raman spectrometer (WITec, Ulm, Germany), energy spectroscopy (EDS, Oxford, UK), and DSA100 (Hamburg, Germany) were used to gain insight into the microstructure and composition of fiber mats.…”

Temperature/Pressure/Humidity Coplanar Integrated SAW Sensor Based on LGS

“…The distinctive peak of C-O and C-C is MMG, which is 287 eV and 285 eV, respectively. Compared to the Go film, the MMG film's surface has richer oxygen-containing functional groups and greater binding energy, which improves hydrophilicity 32 . At the binding energy of 291eV, a new distinctive peak (C-Ti) arises, and a C-Ti bond is created by Mxene and Go, which is consistent with the findings from the Raman spectrum (Figure 5a) 33 .…”

Facile Synthesized Cu–RGO and Ag–RGO Nanocomposites with Potential Biomedical Applications

“…It was shown that with modification of graphene by metal or metal oxide nanoparticles, a synergic effect occurs and the antibacterial action is more effective due to the fine structure, new surface characteristics and durability of the composite obtained [9]. Polymer-graphene based composites also show prospective antibacterial properties [10].…”