Facile Synthesized Cu–RGO and Ag–RGO Nanocomposites with Potential Biomedical Applications

Abstract

In the present study, we report on the facile prepared nanocomposites of reduced graphene oxide RGO with Cu and Ag. The synthesis was performed through an environmentally friendly and easy method by simultaneous reduction in solutions containing Cu2+ or Ag+ and graphene oxide (GO) using zinc powder as a reducing agent in aqueous acidic media. The composites are characterized by powder X-ray diffraction, low-temperature nitrogen adsorption, X-ray photoelectron and FTIR and Raman spectroscopies, as well as Scanning and Transmission electron microscopies. The antibacterial activity of the composites was tested for Staphylococcus aureus, Escherichia coli and antifungal activity for Candida albicans. The cytotoxicity of the materials was studied towards two types of eukaryotic cells—MDCK II and A549 cell lines. The composites obtained consist of homogeneously distributed Cu and Ag nanoparticles on the surface of graphene sheets and manifest good antimicrobial activity and high cytotoxicity. The results clearly show that both metal–RGO composites can be successfully used as antimicrobial and anticancer agents.

Effortless Production, Characterization of Cu/Cu2O Nanostructures using Coconut Water (Cocos nucifera L.) as Bioreductants towards Antibacterial, Antioxidant, and Cytotoxicity on A549 & HeLa Cell lines

“…This is usually the case for slit pores and two parallel plate cracks [47]. The BET surface areas were measured as 53.25 m [51][52][53]. When comparing the results, it was found to that the current studies had a larger surface area and had more active sites, as shown by the BET surface area measurement and pore size distribution analysis.…”

Wearable Electrochemical Microneedle Sensors Based on the Graphene-Silver-Chitosan Nanocomposite for Real-Time Continuous Monitoring of the Depression Biomarker Serotonin

“…Several metal nanoparticles like platinum (Pt), silver (Ag), and iron (Fe) were used to decorate the graphene surface . Out of these, the use of Ag nanoparticles attracted great interest as Ag is highly conductive as well as biocompatible − in nature. Silver nanoparticles were used for the detection of GLU, DNA, hemoglobin, etc.…”

Synergistic effects of hydrothermally decorated Ag nanoparticles over rGO for antibacterial activities

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