Multifunctional nano manganese ferrite ferrofluid for efficient theranostic application

Beeran, Ansar Ereath; Fernandez, Francis; Nazeer, Shaiju S.; Jayasree, Ramapurath S.; John, Annie; Anil, Sukumaran; Vellappally, Sajith; Kheraif, Abdul Aziz Abdullah Al; Varma, P. R. Harikrishna

doi:10.1016/j.colsurfb.2015.11.010

Cited by 24 publications

(26 citation statements)

References 43 publications

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“…Eddy current loss from PANI and Neel’s relaxation from magnetic Fe 0 nanoparticles together contribute to the power dissipation in composite fibres and provide better heating efficiency in this system [ 20 ]. Beeran et al observed an enhancement in hyperthermia activity in HeLa cell population using ferrofluid-based superparamagnetic iron oxide substituted with Mn 2+ and stabilized using trisodium citrate surface coating [ 21 ]. Fe 3 O 4 nanoparticles showed a decrease in the magnetic moment and saturation magnetization on coating with a thermosensitive polymer, poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA) [ 22 ].…”

Section: Introductionmentioning

confidence: 99%

Radio frequency plasma assisted surface modification of Fe3O4 nanoparticles using polyaniline/polypyrrole for bioimaging and magnetic hyperthermia applications

Mol

Beeran

Jayaram

et al. 2021

J Mater Sci: Mater Med

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Surface modification of superparamagnetic Fe3O4 nanoparticles using polymers (polyaniline/polypyrrole) was done by radio frequency (r.f.) plasma polymerization technique and characterized by XRD, TEM, TG/DTA and VSM. Surface-passivated Fe3O4 nanoparticles with polymers were having spherical/rod-shaped structures with superparamagnetic properties. Broad visible photoluminescence emission bands were observed at 445 and 580 nm for polyaniline-coated Fe3O4 and at 488 nm for polypyrrole-coated Fe3O4. These samples exhibit good fluorescence emissions with L929 cellular assay and were non-toxic. Magnetic hyperthermia response of Fe3O4 and polymer (polyaniline/polypyrrole)-coated Fe3O4 was evaluated and all the samples exhibit hyperthermia activity in the range of 42–45 °C. Specific loss power (SLP) values of polyaniline and polypyrrole-coated Fe3O4 nanoparticles (5 and 10 mg/ml) exhibit a controlled heat generation with an increase in the magnetic field.

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Section: Introductionmentioning

confidence: 99%

Radio frequency plasma assisted surface modification of Fe3O4 nanoparticles using polyaniline/polypyrrole for bioimaging and magnetic hyperthermia applications

Mol

Beeran

Jayaram

et al. 2021

J Mater Sci: Mater Med

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“…The applications of ferrofluids in the area of condensed matter are the most diverse due to their properties. These properties have aroused the interest of researchers in the field of chemistry and physics of condensed matter and in the development of nanotechnologies [4], in biomedical [5] and industrial applications. Recent studies have intensified the local colloidal structure in ferrofluids, and have mainly used the technique of small angle scattering; Fu et al (2016) [6] investigated the self-assembly of supercrystals field-induced colloidal structure of core-shell NPs of core-shell iron oxide dispersed in toluene by small angle neutron scattering (SANS); Rozynek et al (2011) [7] the effect of magnetic field on the structure formation in an oil-based magnetic fluid with various concentrations of magnetite particles by SAXS; Campi et al (2019) [8] analyzed nanoparticles clusters of nickelate perovskite by SµXRD (Scanning X-ray micro-Diffraction); Campi et al (2019) [9] investigated hybrid nanoparticles diffusion and nanoscale aggregation, and observed how fractal dimensional changes leading to a mass surface fractal transition (SAXS); and Wandersman et al (2015) [10] field induced anisotropic cooperativity in a magnetic colloidal glass.…”

Section: Introductionmentioning

confidence: 99%

SAXS Analysis of Magnetic Field Influence on Magnetic Nanoparticle Clusters

Paula

2019

Condensed Matter

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In this work, we investigated the local colloidal structure of ferrofluid, in the presence of the external magnetic field. The nanoparticles studied here are of the core-shell type, with the core formed by manganese ferrite and maghemite shell, and were synthesized by the coprecipitation method in alkaline medium. Measures of Small Angle X-ray Scattering (SAXS) performed in the Brazilian Synchrotron Light Laboratory (LNLS) were used for the study of the local colloidal structure of ferrofluid, so it was possible to study two levels of structure, cluster and isolated particles, in the regimes with and without applied magnetic field. In the methodology used here there is a combination of the information obtained in the system with and without magnetic field application. In this way, it is possible to undertake a better investigation of the colloidal dispersion. The theoretical formalism used: (i) the unification equation proposed by Beaucage G.; (ii) the analysis of the radial distribution function p ( r ) and (iii) theoretical calculation of the radius of gyration as a function of the moment of inertia of the spherical of n-nanoparticles.

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“…The average size of the MNPs is 93 ± 5 nm. This size is much larger than manganese ferrite NPs reported earlier for the purpose of MRI or other biomedical objective (Lemarchand et al 2004;Leal et al 2015;Beeran et al 2015;Kang et al 2004;Li et al 2004;Giri et al 2012;Mazarío et al 2016). The hydrodynamic diameter of the CD-PEG-MNPs can be determined by dynamic light scattering (DLS) measurements.…”

Section: Characterization Of Magnetic Nanoparticlesmentioning

confidence: 82%

Cyclodextrin–PEG conjugate-wrapped magnetic ferrite nanoparticles for enhanced drug loading and release

et al. 2018

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Magnetic nanoparticles are envisaged to overcome the impediments in the methods of targeted drug delivery and hence cure cancer effectively. We report herein, manganese ferrite nanoparticles, coated with β-cyclodextrin-modified polyethylene glycol as a carrier for the drug, camptothecin. The particles are of the size of ~ 100 nm and they show superparamagnetic behaviour. The saturation magnetization does not get diminished on polymer coverage of the nanoparticles. The β-cyclodextrin-polyethylene glycol conjugates are characterized using NMR and mass spectrometric techniques. By coating the magnetic nanoparticles with the cyclodextrin-tethered polymer, the drug-loading capacity is enhanced and the observed release of the drug is slow and sustained. The cell viability of HEK293 and HCT15 cells is evaluated and the cytotoxicity is enhanced when the drug is loaded in the polymer-coated magnetic nanoparticles. The noncovalent-binding based and enhanced drug loading on the nanoparticles and the sustained release make the nanocarrier a promising agent for carrying the payload to the target.

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Multifunctional nano manganese ferrite ferrofluid for efficient theranostic application

Cited by 24 publications

References 43 publications

Radio frequency plasma assisted surface modification of Fe3O4 nanoparticles using polyaniline/polypyrrole for bioimaging and magnetic hyperthermia applications

Radio frequency plasma assisted surface modification of Fe3O4 nanoparticles using polyaniline/polypyrrole for bioimaging and magnetic hyperthermia applications

SAXS Analysis of Magnetic Field Influence on Magnetic Nanoparticle Clusters

Cyclodextrin–PEG conjugate-wrapped magnetic ferrite nanoparticles for enhanced drug loading and release

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