Multifrequency bioelectric impedance measurements for predicting body water compartments in duchenne muscular dystrophy

Bedogni, Giorgio; Merlini, Luciano; Ballestrazzi, A.; Severi, S; Battistini, N.

doi:10.1016/0960-8966(95)00015-1

Cited by 22 publications

(11 citation statements)

References 12 publications

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“…Our results agree with the those of Bedogni et al 15,16 demonstrating a significant increase in the percentage of ECW and in the ECW/ICW ratio in the DMD group. Bedogni et al, 16 using deuterium oxide and sodium bromide dilution techniques, showed MFBIA to provide an accurate assessment of total body water in children with obesity, DMD, and juvenile rheumatoid arthritis.…”

Section: Discussionsupporting

confidence: 96%

“…However, these investigators also found the coefficient of variation for ECW measurement to be highest in DMD, at 12.5%, and that DMD patients have a higher ECW/ ICW ratio when compared with controls. 15,16 This group could not determine whether the elevation of this ratio was secondary to an increased fat mass that could not be determined by the measurements of skinfold thickness via calipers or if it was due to dystrophic lean muscle tissue with abnormally low ICW. Our study provides complimentary data to the studies by Bedogni et al 15,16 because of the addition of DEXA measures of FTM, which also determines the presence of intramuscular fat that would normally elude measurement by calipers.…”

Section: Discussionmentioning

confidence: 95%

“…9 -12 Likely due to the underlying consequences of impaired cellular homeostasis, previous studies have determined that DMD patients have a lower percentage of total body water and higher extracellular water to intracellular water (ECW/ICW) ratio compared with controls. [13][14][15][16] However, these previous studies have not adequately measured fat mass and lean body mass. Hence, it has not been possible to discern whether this finding is due to the presence of increased fat mass in DMD subjects or a decreased amount of ICW in muscle cells.…”

mentioning

confidence: 95%

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Body Composition and Water Compartment Measurements in Boys with Duchenne Muscular Dystrophy

McDonald

Carter

Abresch

et al. 2005

American Journal of Physical Medicine &Amp; Rehabilitation

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DMD patients have elevated ECW/ICW ratios compared with obese subjects and nonobese controls. However, obese subjects and nonobese controls had similar ECW/ICW ratios, despite the increased fat tissue mass in obese subjects. This suggests that the elevated ECW/ICW ratios in DMD subjects are not due to increased fat mass but rather some other mechanism, likely impaired cellular homeostasis due to muscle membrane instability. Although MFBIA slightly underestimates lean tissue mass in boys with DMD, it has a potential role as an inexpensive and easy to use measurement tool to measure changes in muscle mass in the clinical setting.

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Section: Discussionsupporting

confidence: 96%

Section: Discussionmentioning

confidence: 95%

mentioning

confidence: 95%

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Body Composition and Water Compartment Measurements in Boys with Duchenne Muscular Dystrophy

McDonald

Carter

Abresch

et al. 2005

American Journal of Physical Medicine &Amp; Rehabilitation

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“…The prediction of TBW and ECW from BIA relies largely on the ECW to intracellular water (ICW) ratio (Deurenberg et al, 1989;Deurenberg et al, 1995). For this reason, subjects with an altered body water distribution between ECW and ICW may need population-speci®c equations in order to have an accurate prediction of body water compartments (Bedogni et al, 1996a;Bedogni et al, 1996b).…”

Section: Introductionmentioning

confidence: 99%

The prediction of total body water and extracellular water from bioelectric impedance in obese children

et al. 1997

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Objectives: To assess the reliability of bioelectric impedance analysis (BIA) for predicting total body water (TBW) and extracellular water (ECW) in obese children. Design: Comparison of ®ve prediction models based on: (i) body weight (Wt), (ii) the impedance (Z) index (ZI height 2 /Z), (iii) the association of Wt and ZI, (iv) the body surface area (SA) to impedance ratio (SA:Z) and, (v) the body volume (V) to impedance ratio (V:Z). Subjects: Thirty obese and 25 control children of 11.2 AE 1.8 y of age. Measurements: TBW and ECW were assessed by deuterium and bromide dilution; Z was measured at frequencies of 5, 50 and 100 kHz. Results: In controls, Wt explained 11% more variance of TBW than ZI (r 2 0.977, SEE 0.9 I, CV 3.8%) and the association of Wt and ZI improved the prediction of TBW only slightly (r 2 0.982, SEE 0.8 I, CV 3.5%). The SA:Z and V:Z indexes explained 6 and 33% less variance of TBW respectively as compared to Wt alone. In obese subjects, ZI explained 4% more variance of TBW than Wt (r 2 0.914, SEE 1.8 I, CV 6.4%) and the SA:Z ratio was the most accurate predictor of TBW (r 2 0.959, SEE 1.2 l, CV 4.4%). However, the increase in the explained variance of TBW associated to the use of the SA:Z ratio was of only 1% as compared to the association of ZI and Wt. The V:Z ratio explained 9% less of variance of TBW as compared to ZI. In both control and obese subjects, the association of Wt and ZI offered the best prediction of ECW (r 2 0.807, SEE 1.564 I and r 2 0.826, SEE 1.035 I, respectively). However, the values of CV were much higher in controls than in obese children (17.5% vs 8.4%) owing to their lower ECW and greater variability in ECW%. ZI was the most accurate predictor of TBW on the pooled sample (n 55; r 2 0.910, SEE 1.932 I, CV 7.4%). However, it was a poor predictor of ECW on the same sample owing to its high CV (n 55; r 2 0.866, SEE 1.806 I, CV 17.0%). Conclusions: The body surface area to impedance ratio is the most accurate predictor of TBW in obese children but the association of ZI and Wt may be of more interest when BIA is used to estimate both TBW and ECW. The impedance index offers a good prediction of TBW but not of ECW in children with different levels of fatness.

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“…A low ICW reflects the low amount of muscle tissues due to factors such as dehydration, nutritional imbalance, hormonal imbalance, or toxicity, whereas a high ECW reflects highly connective and adipose tissue levels [14]. …”

Section: Intracellular/extracellular Watermentioning

confidence: 99%

Assessment of Body Fluid Alteration Using Bioelectrical Impedance in Stroke Patients with Hemiplegia Caused by Cerebral Hemorrhage and Cerebral Infarction

Shin¹,

Kim²,

Hwang³

et al. 2017

Journal of Sensor Science and Technology

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Many stroke patients undergoing rehabilitation therapy require a quantitative indicator for the evaluation of body composition in paretic and non-paretic regions. In this study, the body fluid alteration in the paretic and non-paretic regions of stroke patients with hemiplegia caused by cerebral hemorrhage and cerebral infarction was analyzed using bioelectrical impedance analysis (BIA). Alterations in body fluids were investigated to assess the physical status of the paretic and non-paretic regions of 20 stroke patients with hemiplegia caused by cerebral hemorrhage (7 patients) and cerebral infarction (13 patients). Extracellular water (ECW), intracellular water (ICW), ICW/ECW, total body water (TBW), ECW/TBW, and TBW/fat-free mass were utilized to evaluate the functional status of the paretic and non-paretic regions. Compared with the non-paretic region, the paretic region had high ECW and low ICW. Due to the loss of motor function and nutritional imbalance caused by the stroke, the amount of fat increased while the muscle quantity and quality significantly decreased in the paretic region. Thus, BIA can be a useful tool for quantitatively assessing paretic and non-paretic regions in stroke patients with hemiplegia.

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Multifrequency bioelectric impedance measurements for predicting body water compartments in duchenne muscular dystrophy

Cited by 22 publications

References 12 publications

Body Composition and Water Compartment Measurements in Boys with Duchenne Muscular Dystrophy

Body Composition and Water Compartment Measurements in Boys with Duchenne Muscular Dystrophy

The prediction of total body water and extracellular water from bioelectric impedance in obese children

Assessment of Body Fluid Alteration Using Bioelectrical Impedance in Stroke Patients with Hemiplegia Caused by Cerebral Hemorrhage and Cerebral Infarction

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