Multifocal mucinous neoplasia of the female genital system

Reappraisal of synchronous and multifocal mucinous lesions of the female genital tract: a close association with gastric metaplasia

“…5 Mucinous metaplasia of the tubal epithelium has been described by some authors. 1,2,4,5,7,8,10,13,14 The results of the current study indicate that SMMN-FGT might be a consequence of pyloric gland metaplasia. PGM of the uterine cervix is usually associated with endocervical glandular hyperplasia 15 and is interchangeably called LEGH, which was first described by Nucci et al 16 Although LEGH ⁄ PGM is considered to be a benign condition, 16,17 recent studies have demonstrated that it can be associated with adenocarcinomas, 18,19 emphasizing its significance as a possible precursor of adenocarcinoma.…”

“…In two other cases in the series, benign‐looking foci of mucinous epithelium lined the fallopian tube 5 . Mucinous metaplasia of the tubal epithelium has been described by some authors 1,2,4,5,7,8,10,13,14 …”

“…All mucinous lesions were positive for HIK1083 and ⁄ or MUC6. One patient with minimal deviation adenocarcinoma involving the vagina died of her disease, whereas five patients, including three with microinvasion and three with positive peritoneal cytology or mucinous ascites, were alive without Introduction Synchronous and multifocal mucinous lesions involving the uterine cervix and corpus, fallopian tubes and ⁄ or ovaries [1][2][3][4][5][6][7][8][9][10][11] rarely occur. This type of mucinous lesion, which we have termed synchronous mucinous metaplasia and neoplasia of the female genital tract (SMMN-FGT), demonstrates a spectrum of morphological features ranging from metaplasia, with no nuclear or architectural abnormalities, to invasive mucinous adenocarcinoma, including minimal deviation adenocarcinoma of the cervix.…”

A patient from Zhejiang, China, with synchronous mucinous metaplasia and neoplasms of the female genital tract: A case report

“…Mikami et al defined synchronous mucinous metaplasia and neoplasms of the female genital tract (SMMN‐FGT) for lesions that were widespread over the mucinous glands, including uterine cervix, endometrium, fallopian tube and ovary. The morphology of lesions included benign, malignant and nonneoplastic features . We will report a case of SMMN‐FGT, which contained multifocal benign and invasive mucinous adenocarcinoma involving the uterine cervix, endometrium and left fallopian tube.…”

“…The morphology of lesions included benign, malignant and nonneoplastic features. [2][3][4] We will report a case of SMMN-FGT, which contained multifocal benign and invasive mucinous adenocarcinoma involving the uterine cervix, endometrium and left fallopian tube.…”